431 resultados para Mediadores da inflamação
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Pós-graduação em Ciências Odontológicas - FOAR
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Pós-graduação em Fisiopatologia em Clínica Médica - FMB
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Pós-graduação em Fisiopatologia em Clínica Médica - FMB
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Pós-graduação em Fisiopatologia em Clínica Médica - FMB
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The context political, social and economical determines the material conditions of the individual's cultural formation and it influences in the constitution of the critical conscience and social responsibility. The aim of this paper is to describe the didactic experiences from discussions in classroom with students in disciplines dedicated to information access in the Brazilian librarianship courses from São Paulo State University (Unesp), state of São Paulo, and Federal University of Alagoas (UFAL), state of Alagoas, precisely: Information Dissemination, supplied in 2007 and 2010, and Information Dissemination and Sources, supplied in 2008 and 2009, besides Library and Cultural Action, accomplished of 2008 to 2009. It was noticed, starting from the experience in classroom, that the Librarianship students have low knowledge of the institutions librarians and their services; they told that not to know the main library services before they study them referred disciplines.
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Inflammation is an immune complex-related tissue damage and / or cell caused by chemical, physical, immunological or microbial. The inflammatory process involves a complex cascade of biochemical and cellular events, including awareness and receptor activation, lysis and tissue repair. In general, tissue damage trigger a local inflammatory response by recruiting leukocytes, which release inflammatory mediators. These substances are able to sensitize nociceptors. After synaptic transmission and signal modulation by nociceptive sensory neurons, these signals are perceived as pain. Pain is an experience that involves multiple factors. The route of the supraspinal pain control originates in many brain regions, such as substance periarquedutal gray (PAG), median raphe nucleus and rostral ventromedial medulla (RVM) and have a critical role in determining the chronic and acute pain. Anti-inflammatory drugs (NSAIDs) are used to control inflammation, which inhibit the inflammatory mediators, but can cause side effects such as stomach ulcers and cardiovascular damage. An alternative for the treatment of pain and inflammation is the use of plant species. The genus Eugenia belongs to the family Myrtaceae, one of the largest botanical families of expression in the Brazilian ecosystems. From the pharmacological point of view, studies of similar species crude extracts showed the presence of anti-inflammatory, analgesic, antifungal, hypotensive, antidiabetic and antioxidant activity of some species. As a class of importance in therapeutic phytochemical, the flavonoids has represented an important group with significant anti-inflammatory and gastroprotective, and are present in a significant way in the chemical composition of genus Eugenia. The project´s overall objective is to evaluate the antinociceptive and anti-inflammatory activities from hydroalcoholic extract of leaves of Eugenia punicifolia (EHEP). In this work we performed acute toxicity ...
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Pós-graduação em Genética - IBILCE
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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In the present paper, it is presented a general view about who they are and the activities science centers and museums mediators develop. The literature points out to the diverse roles attributed to these actors and that the presence of this type of professional is a consolidated practice in non-formal educational institutions. Data obtained among the mediators of a science center during mediated school visits are also presented and discussed, focusing in the role attributed to these professionals, with the objective of characterizing their actions during these visits. The data obtained and analyzed showed that during school visits, the roles that are attributed to the mediators are: (a) mediation of the knowledge involved in the expositions; (b) explanation of the scientific concepts involved in the expositions; (c) presentation of the thematic spaces; (d) reception and organization of groups of visitors; (e) preservation of the physical and moral integrity of the visitors, and the integrity of the physical spaces and their equipments; (f) complementation of the school knowledge, and (g) diffusion of the scientific knowledge.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)