Estudo histomorfométrico do processo de cicatrização óssea em defeitos cirúrgicos de camanho crítico em calvárias de ratos preenchidos com polímero de mamona

Objectives: The aim of this study was to evaluate the behavior of the polymer histomorphometrically castor during the healing process of defects of critical size calvarial preparations in rats. Materials and Methods: Twenty animals underwent a surgical procedure that was to be held in the calvaria of each animal a critical defect of 8 mm in diameter with a drill trephine. The rats were divided into two groups according to the following procedures: group C received no treatment and the bone defect site was filled with blood clot, group M, the bone defect was filled with castor oil polymer particles. The animals were sacrificed 180 days after the surgical procedures. After routine laboratory procedures the specimens were subjected to analysis histomorphometric. Results: In groups C the newly formed bone tissue was well developed, with adjacent areas of osteoid matrix rich in osteoblasts, and restricted to the vicinity of the edges of the defect. In animals of group M was observed newly formed lamellar bone tissue restricted to the vicinity of the defect edges and particles of polymer Castor distributed throughout the defect. There was a higher percentage of newly formed bone area was statistically significant in group C compared to animals in group M. Conclusions: Within the limits of this study can conclude that the castor oil polymer is biocompatible and had kept the area during the healing of critical size defects in surgically prepared rat calvariae.

Estudo histomorfométrico do processo de cicatrização óssea em defeitos cirúrgicos de tamanho crítico em calvárias de ratos preenchidos com polímero de mamona

Objectives: The aim of this study was to evaluate the behavior of the polymer histomorphometrically castor during the healing process of defects of critical size calvarial preparations in rats. Materials and Methods: Twenty animals underwent a surgical procedure that was to be held in the calvaria of each animal a critical defect of 8 mm in diameter with a drill trephine. The rats were divided into two groups according to the following procedures: group C received no treatment and the bone defect site was filled with blood clot, group M, the bone defect was filled with castor oil polymer particles. The animals were sacrificed 180 days after the surgical procedures. After routine laboratory procedures the specimens were subjected to analysis histomorphometric. Results: In groups C the newly formed bone tissue was well developed, with adjacent areas of osteoid matrix rich in osteoblasts, and restricted to the vicinity of the edges of the defect. In animals of group M was observed newly formed lamellar bone tissue restricted to the vicinity of the defect edges and particles of polymer Castor distributed throughout the defect. There was a higher percentage of newly formed bone area was statistically significant in group C compared to animals in group M. Conclusions: Within the limits of this study can conclude that the castor oil polymer is biocompatible and had kept the area during the healing of critical size defects in surgically prepared rat calvariae

A proporção de plasma rico em plaquetas/enxerto ósseo autógeno pode influenciar o reparo ósseo de defeito de tamanho crítico: estudo radiográfico em calvária de ratos

Introduction: It has been suggested that bone grafts combined with platelet rich plasma (PRP) present greater density than bone grafts without PRP after healing process. However, this result may depend on proportion PRP/autogenous bone (AB) graft used. Objective: The purpose of this study was to analyze radiographically the influence of the proportion PRP/particulate autogenous bone (AB) graft on bone healing in surgically created criticalsize defects (CSD) in rat calvaria. Material and method: 50 rats were divided into 5 groups: C, AB, AB/PRP-50, AB/PRP-100 and AB/PRP-150. A 5 mm diameter CSD was created in the calvarium of each animal. In Group C the defect was filled by blood clot only. In Group AB the defect was filled with 0.01 mL of AB graft. In groups AB/ RP-50, AB/PRP-100 and AB/PRP-150 the defects were filled with 0.01 mL of AB graft combined with 50, 100 and 150 µL of PRP, respectively. All animals were euthanized at 30 days post-operative. Standardized radiographic images of the rat calvaria were obtained using Digora System (Soredex, Finland). The images were evaluated by three examiners using scores that indicated the percentage of radiopacity of the defect. The obtained data were subjected to statistical analysis (Kruskal-Wallis test, p < 0.05). Result: Group C presented radiopacity significantly lower than groups AB, AB/PRP-50, AB/PRP-100 and AB/PRP-150. Group AB/PRP-50 showed radiopacity significantly greater than groups AB/PRP-100 and AB. Conclusion: It can be concluded that the proportion PRP/AB graft influences bone healing in CSD in rat calvaria.

A competência em informação como fator crítico de sucesso para a pesquisa na área de ciência da informação: transferência de princípios para reflexão

This study is to provide parameters from theoretical and exploratory research in the creation and institutionalization of information science to establish a link with Information Literacy. Approaches are presented in which contributions allow us to understand the relationships and kinds of science in general and their applicability to the population studied, since these theories have a big relationship with the deepening of the area and their social, cultural and economic relationships. We hope to contribute with selective reference to assist the understanding of the issues arising from information science and the knowledge generated by its researchers. This requires developing new skills of access and use of information, providing an interaction between information literacy and knowledge building in Information Science.

Subjetividade e intencionalidade: Searle crítico de Dennett

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Glauber Rocha e a dimensão do confronto de ideias na cena midiática: estudo das estratégias do jovem crítico de cinema no Jornal da Bahia no final dos anos 1950

In late 1950, the young Glauber Rocha, still without having directed any of his films, becomes the main cultural critic of the Jornal da Bahia in Salvador, Bahia. His film critic activity falls within the symbolic local disputes and his texts published become an active voice in the cultural field of Bahia. With a considerable apparatus of the press in his favor, the performance of the young critic Glauber Rocha allows to discuss: the role of public intellectual and media production and dissemination of ideas by the newspapers at the turn of the 1950s to the 1960s, a time of intense political, social and cultural changes in Brazil.

O paradigma dualista da hanseníase controle ou eliminação: o período crítico de 2000 a 2005

One of the main tendencies of leprosy worldwide is the simultaneous action of non governmental organizations and official agencies operating eventual different strategies. This paper aims to contribute to such question focusing on some outstanding aspects of respective contemporary evolution. METHODS Application of bibliographic review and contents analysis techniques to primary data from a circumstancial set of open circulation specific publications. RESULTS Successive disagreements registered between both parts refer to the objective to be attained by the fight against the disease, if control or elimination. CONCLUSIONS New perspectives of jointed actions are being searched for now when priority on endemics control is more realistically assumed and social determination is been really considered.

Legislação ambiental incidente sobre cemitérios do Estado de São Paulo

A expansão urbana acarreta a necessidade de mitigações ambientais, em que um planejamento do uso do solo, bem como seu processo de ocupação traz a necessidade também de estudos para viabilizar tais ações. Nesse processo de expansão, os cemitérios necessitam de maiores atenções, já que evidenciaram indícios de contaminações no solo e fontes de água próximas. Atualmente, o CONAMA (Conselho Nacional de Meio Ambiente) possui duas resoluções que discorrem sobre os aspectos construtivos, visando controlar os resíduos existentes, tais como o Liquame da Coliquação (também conhecido por Necrochorume), um dos responsáveis pela contaminação do solo e aquíferos subterrâneos. Tendo esse escopo em pauta, este trabalho exibe um levantamento da legislação que incide sobre a implantação e regularização de cemitérios no estado de São Paulo.

Estimativas da radiação difusa horária incidente em superfícies inclinadas com base na transmissividade atmosférica

Evaluated statistical equations estimates (based on radiometric fractions) of the hourly diffuse radiation incident on inclined surfaces for the North to 12.85, 22.85 and 32.85°, the climate and geographical conditions of Botucatu, SP. The database was generated from April/1998 to December/2007, with measures in the three tilted surfaces in different periods, but concomitant to the horizontal plane. In the validation of the equations were used indicative statistics MBE (mean absolute error), RMSE (square root mean square error) and index adjustment (d) for three inclinations and conditions of sky coverage. The increased angle of inclination of the surface led to increased scattering of hourly values for the coefficient of atmospheric transmissivity of diffuse radiation for inclined and horizontal surfaces. Estimates of diffuse radiation on the basis of hourly tilted horizontal global radiation occur for quadratic polynomial models, which adjust K'Dβ maximum values of between 0.14 and 0.30 for winter and summer when KTH varies between 0.40 and 0.66, indicating that energy, the highest values of diffuse radiation occur in partly cloudy sky conditions and / or partially open. The increase in atmospheric transmissivity decreases the performance of annual and monthly equations at all inclinations.

Variabilidade temporal e espacial da precipitação incidente sobre a unidade de gerenciamento de recursos hídricos Sorocaba e Médio Tietê e anomalias

Pós-graduação em Ciências Ambientais - Sorocaba