De palanque: as crônicas de Artur Azevedo no diário de Notícias (1885/1886)

Esequiel Gomes da Silva reúne neste livro vários textos jornalísticos do maranhense Artur Azevedo, considerado o primeiro grande dramaturgo brasileiro. O período focado por Silva foi um dos mais fecundos na carreira jornalística do escritor, que através de suas crônicas traçou, com verve e simpático distanciamento, um amplo painel da sociedade e da vida política e cultural do Rio de Janeiro, a efervescente capital imperial. O livro traz, além das crônicas publicadas nesse período - transcritas integralmente, com ortografia atualizada - uma percuciente análise sobre a produção intelectual de Artur Azevedo, enfatizando, porém, sua atuação enquanto crítico de jornais. A obra ainda oferece uma caracterização geral das crônicas e se debruça sobre o processo de elaboração formal e sobre os recursos de comicidade utilizados pelo escritor. O trabalho também possibilita compreender como essas crônicas serviram de ferramenta de intervenção artística, cultural, política e social, terminando por mostrar um Artur Azevedo surpreendentemente engajado nos assuntos do país e empenhado no fortalecimento da cultura brasileira

EEG signal classification for epilepsy diagnosis via optimum path forest - A systematic assessment

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

A path- and label-cost propagation approach to speedup the training of the optimum-path forest classifier

In general, pattern recognition techniques require a high computational burden for learning the discriminating functions that are responsible to separate samples from distinct classes. As such, there are several studies that make effort to employ machine learning algorithms in the context of big data classification problems. The research on this area ranges from Graphics Processing Units-based implementations to mathematical optimizations, being the main drawback of the former approaches to be dependent on the graphic video card. Here, we propose an architecture-independent optimization approach for the optimum-path forest (OPF) classifier, that is designed using a theoretical formulation that relates the minimum spanning tree with the minimum spanning forest generated by the OPF over the training dataset. The experiments have shown that the approach proposed can be faster than the traditional one in five public datasets, being also as accurate as the original OPF. (C) 2014 Elsevier B. V. All rights reserved.

Crises cambiais e fragilidade financeira externa: uma interpretação minskyana aplicada à economia brasileira entre 1999 e 2013

Pós-graduação em Economia - FCLAR

O agrupamento de interesse econômico como forma de colaboração empresarial para o direito brasileiro

Pós-graduação em Direito - FCHS

Autonomic control of heart rate during orthostasis and the importance of orthostatic-tachycardia in the snake Python molurus

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Genotoxicity and cytotoxicity induced by municipal effluent in multiple organs of Wistar rats

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Mimosa (Mimosa caesalpiniifolia) prevents oxidative DNA damage induced by cadmium exposure in Wistar rats

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A todo vapor: o projeto de uma websérie cômica

Esta pesquisa apresenta as etapas da elaboração do projeto A Todo Vapor. O projeto consiste no desenvolvimento de uma websérie cômica de formato mockumentary baseada na Empresa Júnior de Rádio e TV da UNESP. O projeto conta com: a sinopse da série; perfil dos personagens; sinopses dos cinco episódios da temporada; projeto de quatro programas spin-offs que permeiam a websérie; argumento do piloto; e também roteiro completo do piloto

Galectin-1 exerts inhibitory effects during DENV-1 infection

Dengue virus (DENV) is an enveloped RNA virus that is mosquito-transmitted and can infect a variety of immune and non-immune cells. Response to infection ranges from asymptomatic disease to a severe disorder known as dengue hemorrhagic fever. Despite efforts to control the disease, there are no effective treatments or vaccines. In our search for new antiviral compounds to combat infection by dengue virus type 1 (DENV-1), we investigated the role of galectin-1, a widely-expressed mammalian lectin with functions in cell-pathogen interactions and immunoregulatory properties. We found that DENV-1 infection of cells in vitro exhibited caused decreased expression of Gal-1 in several different human cell lines, suggesting that loss of Gal-1 is associated with virus production. In test of this hypothesis we found that exogenous addition of human recombinant Gal-1 (hrGal-1) inhibits the virus production in the three different cell types. This inhibitory effect was dependent on hrGal-1 dimerization and required its carbohydrate recognition domain. Importantly, the inhibition was specific for hrGal-1, since no effect was observed using recombinant human galectin-3. Interestingly, we found that hrGal-1 directly binds to dengue virus and acts, at least in part, during the early stages of DENV-1 infection, by inhibiting viral adsorption and its internalization to target cells. To test the in vivo role of Gal-1 in DENV infection, Gal-1-deficient-mice were used to demonstrate that the expression of endogenous Galectin-1 contributes to resistance of macrophages to in vitro-infection with DENV-1 and it is also important to physiological susceptibility of mice to in vivo infection with DENV-1. These results provide novel insights into the functions of Gal-1 in resistance to DENV infection and suggest that Gal-1 should be explored as a potential antiviral compound.

Os jogos do texto ou as facetas da escrita?: gênero policial, intertextualidade e literatura francesa em Bufo & Spallanzani (1985) de Rubem Fonseca

Pós-graduação em Letras - FCLAS

Sevoflurane induces DNA damage whereas isoflurane leads to higher antioxidative status in anesthetized rats

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Metalloproteinase inhibition protects against reductions in circulating adrenomedullin during lead-induced acute hypertension

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Two new species of the feather mite genus Analloptes (Trouessart, 1885) (Acariformes: Astigmata: Xolalgidae) from passerines (Aves: Passeriformes) in Brazil

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)