Avaliação da resposta imune de células dendríticas e subpopulações de linfócitos T no modelo experimental de Yersinia pseudotuberculosis

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Impacto de drogas antiplaquetárias na doença e no reparo periodontal experimental em ratos

Pós-graduação em Odontologia - FOAR

Experimental RTM manufacturing analysis of carbon/epoxy composites for aerospace application

The success of manufacturing composite parts by liquid composite molding processes with RTM depends on tool designs, efficient heat system, a controlled injection pressure, a stabilized vacuum system, besides of a suitable study of the preform lay-up and the resin system choice. This paper reports how to assemble a RTM system in a laboratory scale by specifying heat, injection and vacuum system. The design and mold material were outlined by pointing out its advantages and disadvantages. Four different carbon fiber fabrics were used for testing the RTM system. The injection pressure was analyzed regarding fiber volume content, preform compression and permeability, showing how these factors can affect the process parameters. The glass transition temperature (Tg) around 203 ºC matched with the aimed temperature of the mold which ensured good distribution of the heat throughout the upper and lower mold length. The void volume fraction in a range of 2% confirmed the appropriate RTM system and parameters choice.

Avaliação dos mecanismos de ação envolvidos na atividade antiulcerogênica de Serjania marginata frente á doença ulcerosa péptica experimental

Pós-graduação em Ciências Biológicas (Farmacologia) - IBB

Análise teórica e experimental do comportamento de vigas de alvenaria estrutural armada sujeitas à flexão simples

Pós-graduação em Engenharia Civil - FEIS

Efeito da curcumina na angiogênese em modelo experimental de câncer de mama

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Effects of calcium salts of soybean oil on factors that influence pregnancy establishment in Bos indicus beef cows

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Analysis of the risk factors relating to cows' resistance to Rhipicephalus microplus ticks during the peripartum

This study aimed to evaluate season, breed, number of lactations and milk production as risk factors relating to Rhipicephalus microplus infestation in dairy cows during the peripartum. Eighty-four animals were randomly selected through proportional stratified sampling. All engorged and partially engorged female R. microplus specimens measuring 4.5-8.0 mm were counted during the 5 weeks before calving, calving week and 5 weeks after calving. The peripartum had a significant effect [calving (p < 0.05; prevalence ratio (PR)= 3.12) and post calving (p < 0.05; PR = 2.02)] on R. microplus infestation. Although the average tick count was higher during the rainy season than during the dry season, there was no significant difference (p = 0.055; PR = 0.63). The average R. microplus count was significantly higher (p < 0.05; PR = 2.10) in Bos taurus animals, followed by F1 (p < 0.05; PR = 1.64) and Girolando (p < 0.05; PR = 1.39). The average R. microplus count was significantly higher (p < 0.05; PR = 0.97) in first-lactation animals, followed by those at the second, third and, fourth or subsequent lactation. Milk production showed a negative correlation with R. microplus count, such that high-production animals were significantly (p = 0.003; PR = 2.04) more vulnerable to infestation than were low-production animals. First-lactation and high-production B. taurus animals had greatest vulnerability to R. microplus infestation over the peripartum period, and constituted the at-risk group in the dairy herd.u

Avaliação experimental de eficiência térmica de um recuperador de calor e caldeira em um sistema de cogeração

Pós-graduação em Engenharia Mecânica - FEB

Avaliação do uso de fantomas antropomórficos na análise experimental dos fatores que afetam o contraste de imagens radiográficas

This experimental study aimed the evaluation of the use of anthropomorphic phantoms in the analysis of the influence of the acquisition parameters in the contrast of radiographic images. The analyzed factors were the variation of the peak kilovoltage (kVp) and the product of the filament circuit by the time of exposition (mAs). The influence of these factors was verified for different anthropomorphic phantoms: foot, knee and chest. The image contrast behavior with the simulators was compared to values obtained with the use of an aluminum ladder being the behavior of this reference for analysis and discussion. To assure the reproducibility of images, quality control tests were made and evaluation of procedure conditions before the experiments. The results obtained are shown in a scale of images where it was possible to evaluate the impact in the darkness of images. Regions with different compositions were analyzed which were different in image, this way the values of optical density and contrast are represented as charts and graphics. We conclude that the use of anthropomorphic phantoms in the evaluation of the influence of tension of the tube and time of exposition in the contrast of the radiographic images is not indicated for a quantitative analysis through optical density, once they present incompatible results with the data as reference as the aluminum ladder even so these simulators present a great property in qualitative analysis regarding the differentiation of structures and subjective evaluations

Avaliação da influência do estresse em modelo experimental de colite por administração de Ácido Trinitrobenzenosulfônico (TNBS) em concentração subinflamatória

Inflammatory bowel disease (IBD) is a chronic and relapsing disease caused by exaggerated response of the immune system. It represents a significant health problem by limiting the quality of life and being the main risk factor for colorectal cancer. Despite of its importance, the high worldwide incidence and being the object of research for several decades, the etiology remains unknown. Studies indicates an interaction between genetic and environmental factors which together with the intestinal microbiota, leads to an uncontrolled immune response. One of the aggravating environmental factors often discussed is stress, as the daily life of the population in general is increasingly rushed. In order to demonstrate the influence of stress on IBD, this study aimed to standardize an experimental model of colitis induced by instillation of a trinitrobenzene sulfonic acid (TNBS) noninflammatory concentration plus exposure to stress that intensify the inflammation. Therefore, an experiment was done to determine what would be the noninflammatory concentration. In this step, four different concentrations of TNBS (1, 6, 12.5 or 40mg/ml) were tested and the lowest concentration capable of inducing a noninflammatory response in the gut was defined as 1 mg/ml. Then, a second experiment was performed which induced colitis and exposed the animals to restraint stress. The results, however, showed that this stimulus was not enough to exacerbate the damage caused by the 1 mg/ml concentration of TNBS in the colon. With some changes in the protocol, the third experiment associated cold and restraint, as well as changes on the day of euthanasia, which occurred immediately after the stress session. The results of myeloperoxidase activity measurement were unexpected due to the noninflammatory concentration of TNBS caused an intestinal inflammation similar to the concentration of 40 mg/ml. However, the results of glutathione quantification and the corticosterone ...

Marketing experimental: análise de conteúdo na indústria automobilística

The screen work seeks to illustrate the experiential marketing strategies, relating these concepts within the automotive industry. From the methodology of content analysis, success stories of the automotive industry have been analyzed in the light of experimental marketing theories to elucidate the strategies of organizations with their target audience. The objectives aimed at understanding and studying experiential marketing within the market scenario, identify its main characteristics and applicability. The main results stand out that sensory experiences provided by experiential marketing can be the differentiating factors between organizations, especially, those of the automotive sector

Terminalia catappa L.: A medicinal plant from the Caribbean pharmacopeia with anti-Helicobacter pylori and antiulcer action in experimental rodent models

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Experimental Autoimmune Encephalomyelitis Development Is Aggravated by Candida albicans Infection

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Septic arthritis: immunopathogenesis, experimental models and therapy

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)