Glicerina na alimentação de cordeiros 1/2 Dorper 1/2 Santa Inês: consumo, digestibilidade, desempenho, características quantitativas da carcaça e qualitativas da carne

Pós-graduação em Zootecnia - FCAV

Efeitos da ingestão de Yacon (Smallanthus sonchifolius) sobre o processo de carcinogênese de cólon induzido pela 1, 2-dimetilhidrazina em ratos wistar

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Propriedades magnéticas do modelo de Ising bidimensional em uma rede bipartida de spins 1/2 e 1: um estudo de ferrimagnetismo com vacâncias

Pós-graduação em Ciência e Tecnologia de Materiais - FC

Estudo da influência dos genótipos 1 e 3 do vírus da hepatite C sobre os indicadores do metabolismo lipídico em hepatopatas crônicos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Espalhamento e estados ligados de partículas de spin 1/2 em um potencial degrau suave com acoplamentos escalar e vetorial

Pós-graduação em Física - FEG

Farmacocinética pré-clínica do composto 1-(2,6-diclorofenil)indolin-2-ona (DICCIC), pró-fármaco de diclofenaco

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Inclusive search for a vector-like T quark with charge 2/3 in pp collisions at root s=8 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Indoleamine 2,3-dioxygenase (IDO) Activity in Placental Compartments of Renal-Transplanted Pregnant Women

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Theoretical insight into the mechanism for the inhibition of the cysteine protease cathepsin B by 1,2,4-thiadiazole derivatives

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Ácido 2,3,5-tri-iodobenzoico (TIBA) na micropropagação de abacaxizeiro 'IAC Gomo-de-Mel'

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Defining suitable reference genes for RT-qPCR analysis on human sertoli cells after 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Formation of 1,N-6-etheno-2 '-deoxyadenosine adducts by trans,trans-2,4-decadienal

trans,trans-2,4-Decadienal (DDE) is an important breakdown product of lipid peroxidation. This aldehyde is cytotoxic to mammalian cells and is known to be implicated in DNA damage. Therefore, attempts were made in this work to assess the reactivity of DDE with 2'-deoxyadenosine (dAdo). It was shown that DDE is able to bind to 2'-deoxyadenosine, yielding highly fluorescent products. Besides 1,N-6-etheno-2'-deoxyadenosine (epsilon dAdo), two other related adducts, 1-[3-(2-deoxy-beta-D-erythro-pentofuranosyl)3H-imidazo[2,1-i]purin-7-yl]-1,2,3-octanetriol and 1-[3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3H-imidazo[2,1-i]purin-7-yl]-1,2-heptanediol, were isolated by reverse phase high-performance liquid chromatography and characterized on the basis of their UV, fluorescence, nuclear magnetic resonance, and mass spectrometry features. The reaction mechanism for the formation of the DDE-2'-deoxyadenosine adducts involves 2,4-decadienal epoxidation and subsequent addition to the N-2 amino group of 2'-deoxyadenosine, followed by cyclization at the N-1 site. Adducts differ by the length of carbon side chain and the number of hydroxyl groups. The present data indicate that DDE can be epoxidized by peroxides, and the resulting products are able to form several adducts with 2'-deoxyadenosine and/or DNA. Endogenous DNA adduct formation can contribute to the already reported high cytotoxicity of DDE to mammalian cells.

Goppa codes through polynomials of B[X;(1/2^2)Z_0] and its decoding principle

In this paper, we present a decoding principle for Goppa codes constructed by generalized polynomials, which is based on modified Berlekamp-Massey algorithm. This algorithm corrects all errors up to the Hamming weight $t\leq 2r$, i.e., whose minimum Hamming distance is $2^{2}r+1$.

Toxicologia reprodutiva de ratos adultos expostos ao 2,3,7,8-Tetraclorodibenzo-P-Dioxina (TCDD) in útero

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)