Uso de células-tronco para o tratamento de tendinite em eqüinos

Brazil has the fourth largest horse herd in the world, this is due the recognition and appreciation that the different equestrian games are having within the country. Injuries of the tendon, especially in the digital flexor tendon, are the main cause of athletic life reduction among horses. The treatment of tendinitis in horses seeks full recovery of the damage tissue reestablishing the function previously lost, however conventional treatments have proven to be ineffective when considered the quality of the scar tissue and the rate of recurrence. Due to this, the use of adult stem cells to the treatment of musculoskeletal injuries of horses has been studied for some time. This method of treatment consists of aspiration of bone marrow or removal of subcutaneous fat tissue and implantation of these cells in the injured tissue. After obtaining the bone marrow the implantation can be performed with total bone marrow, with the mononuclear fraction of MSC or with cells cultured in vitro. From the fat tissue is used the stromal vascular fraction obtained by collagenase digestion, followed or not by cell culture. According to some studies, cell therapy with material obtained from bone marrow or adipose tissue has shown to be viable, given that these materials are abundant in repair components such as mesenchymal stem cells (MSC), growth factors and other components of the collagen matrix. Several studies using both types of cells have shown great potential and promising clinical results. However, knowledge of the biology and characterization of these cells remain largely unknown, and therefore is needed great care and caution when using stem cells for the treatment of musculoskeletal disorders in horses

Marketing em Medicina Veterinária

This paper will address the main concepts os modern marketing: marketing in businnes analysis, internal marketing, marketing plan, and relationship marketing and personal, always drawing a parallel with the reality of the veterinarian

Valores hematológicos em Geochelone carbonária (Jabuti)

Hematology has a great importance in assessing the health of all animals, including reptiles, since it aids in the diagnosis of certain diseases and help to monitor patient's clinical evolution, although studies and articles in this area are rare, even with the increasing number of calls of these animals in veterinary clinics. Moreover, there are a lot of environmental and individual factors, which influence the hematological values of this group, such as age, sex, stress levels, nutrient levels and season which the exam was made, among others. For these reasons studies that aimed to evaluate the reference values of some specie, are essential to increase the knowledge in the field and to assist on the clinical approach. This paper aim’s to study the patterns of Hematology of Tortoise (Geochelone carbonaria) seeking the greater knowledge of clinical pathology of this species and increasing the possibilities for diagnosis, monitoring clinical outcome, and assessment of the general state and treatment

Acupuntura no tratamento de discopatias intervertebrais em cães

The intervertebral disc disease is considered a major neurological disorder involving the spinal cord, being a disease commonly seen in dogs in clinical practice of small animals. The pathophysiology of most discopathies have not been fully elucidated, but it is known that the symptoms observed will depend on the severity of spinal cord compression and location of spinal injury, ranging from localized pain to complete paralysis. Through a detailed clinical examination and laboratory tests, we choose the most appropriate treatment for each patient, which can be conservative, through the use of anti-inflammatories, analgesics and acupuncture or surgical, through decompression techniques. Acupuncture, therapeutic method of ancient Chinese medicine, uses the stimulation of specific points on the body in order to balance the body's physiological. The action mechanism of acupuncture in discopathies has not been fully elucidated, but its analgesic effects, anti-inflammatory and restoration of sensory and motor function are known, showing results as good as surgical therapy

Subluxação atlantoaxial canina

The atlantoaxial subluxation or luxation is an instability of this articulation that produces excessive flexion of this joint causing the cranial aspect of the axis to rotate dorsally into the vertebral channel with subsequent spinal cord compression. This disorder is most commonly found in young small breed dogs. The diagnosis of this disease is done by survey radiographs, where there is a larger distance between the atlas dorsal arch and the axis spinal process characterize the atlantoaxial subluxation. Surgical stabilization is the treatment of choice and multiple implants show the best results to stabilize the atlantoaxial joint. The main complications are sudden death or implant failure. The sudden death happens because of cardiorespiratory arrest and it is most likely caused by brainstem iatrogenic trauma. However, a larger study comparing different surgical stabilization techniques should be performed to evaluate relative success rates in dogs that have the same initial neurologic status

Hipotireoidismo em cães: aspectos gerais

Hypothyroidism is a common endocrine disorder in dogs caused by insufficient production and secretion of thyroid hormones. Most affected dogs have primary hypothyroidism that results from lymphocytic thyroiditis, idiopathic thyroid atrophy, or more rarely, neoplastic destruction. Secondary hypothyroidism resulting from inadequate secretion of thyrotropin (thyroid-stimulating hormone –TSH) from the pituitary gland is less commonly recognized. Tertiary hypothyroidism resulting from a deficiency of hypothalamic thyrotropin-releasing hormone (TRH) has not been documented in dogs. The diagnosis of hypothyroidism in dogs is made on the basis of clinical findings, results of routine laboratory and thyroid gland function tests and response to thyroid hormone replacement. Unfortunately, these tests have high sensitivity, but low specificity, for use in the diagnosis of hypothyroidism. Thyroid hormone supplementation is indicated for the treatment of confirmed hypothyroidism and for the diagnoses of the disease through clinical response to trial therapy

Fístula infraorbitária associada à doença periodontal em cães

Veterinary Dentistry has grown considerably in recent years. This growth, associated to increase of knowledge among pet owners regarding responsible ownership of their pets, resulted in growing concern about the oral health of the animals that already can be observed at veterinary clinics. Among the oral diseases in dogs, infraorbital fistula, so called carnassial” fistula, is a periapical osteolytic lesion of the fourth premolar (4 SPM), often associated with periodontal disease. In its early stages, is characterized clinically by a swelling in the region of the jawbone before the formation of the fistula and leakage of a liquid serosanguineous or purulent secretion. Because of these clinical features, it is often misdiagnosed as a skin condition unrelated to the teeth. It is very important to obtain intraoral radiographs to confirm the diagnosis for performing the most appropriate treatment, according to the cause of the injury

Utilização da acupuntura no tratamento de cães com discopatia intervertebral

The intervertebral disc diseases have a high casuistic in clinical routines veterinary among dogs. These conditions can cause pain, paresis or paralysis of limbs depending on the degree of injury. Clinical signs are not limited to the intervertebral disc, other anatomical parts are included. In conventional medicine, treatment may be surgical or clinical, by the use of corticosteroids with muscle relaxants. Acupuncture was an alternative to treating these diseases due to its anti-inflammatory and analgesic effects. Although there are few studies for the treatment of discopathies, acupuncture triggers the release of substances such as dynorphins, beta-endorphins and serotonin, among others; that act inhibiting somatic and visceral pain. Electroacupuncture is used to potentiate the effects of acupuncture. It can be performed with different frequencies according to the clinical evolution. However there are different opinions related to the greater efficacy in relation to acupuncture. The restraint and monitoring of the treated animal are important factors for its recovery. The association between acupuncture and conventional treatment (surgical or clinical) achieved better results than acupuncture alone. This proves that acupuncture can be considered an option in order to minimize the complications of surgery or assist in patient recovery

Eletroquimioterapia em cães e gatos

The eletrochemotherapy is a new treatment option for neoplasms that involves the application of chemotherapeutic drugs endovenously or intralesionally, associated with local severe and short duration electrical pulses. The electrical pulses promote destabilization of the cell membrane, causing transitory pore formation and facilitating the entry of chemotherapeutic agents inside the cells, increasing its cytotoxicity. This therapy allows for lower doses of chemotherapy drugs compared to conventional chemotherapy, resulting in the decrease of side effects and costs of treatment. The eletrochemotherapy has proved effective in the treatment of cancer regardless of its histological origin and location. This review aims to highlight possibilities to use this treatment in Veterinary Oncology

Síndromes paraneoplásicas hematológicas em cães

Tumoral masses can cause several direct problems in the organism, such as invading organs and altering their functions, leading to other problems such as the Paraneoplastic syndrome. The paraneoplastic syndrome is an alteration in the structure and function of the body due to the non-invasive actions of the tumor, for example, liberating hormones, peptides, cytokines and leading to cross reactions between normal tissues. The syndrome can affect different locations in the body, being that some are indicative of specific tumors, however the interpretation of the clinical and pathological findings referring to this syndrome should be utilized in the diagnostic and treatment. In the hematological paraneoplastic syndrome, there are alterations that occur due to indirect actions of the tumor on the blood cellular elements and the coagulation system, and that are generally detected in routine clinical and laboratorial exams. This study objective is to aboard some hematological paraneoplastic syndromes in dogs such as: anemia, thrombocytopenia, neutrophilic leukocytosis, hypergammaglobulinemia and erythrocytosis, emphasizing the different etiologies that may assist in differential diagnosis and the principal neoplasm related to this syndrome. Besides this, the early discovery and treatment of the paraneoplatic syndrome is important as the tumor itself, as it improves the prognostic and quality of life of the patient

Alterações hematológicas em cães e gatos sob estresse

The leukocyte count interpretation on the blood helps on understanding about the possible dysfunction showed by the animal. In general, an abnormal leukogram allows the identification of pathological process. A lot of events lead to an increase in the number of neutrophils, among then, inflammatory process, infection and stress. Dependent on the stress mediator that the animal is submited, the leukocyte alteration will be different. Is important to know how the stress acts on the animal organism, changing the hematological parameters, in order to avoid mistakes on diseases‟ diagnosis. It‟s known that after a stress situation, it‟s expected that stress leukogram appears on the hemogram of the animal. However there are different kinds of stress with different responses. It‟s believed that when the animal is under an acute stress situation, a clinical picture of physiologic leukocytosis occurs which is mediated by the epinephrine. This is characterized by neutrophilia, lymphocytosis, monocytosis and eosinofilia. The physiologic leukocytosis is a transient alteration in the leukogram that occurs within minutes of the stimulus and due to fleeting effect of catecolamines it resolves within 20 to 30 minutes. However, if the animal is under chronicle stress, as solitude, it „s expected to find the stress leukogram on the leukogram, that can be noted especially in dogs. The stress leukogram is characterized by leukocytosis, neutrophilia, lymphopenia, monocytosis and eosinopenia. This kind of stress is induced by the glucocorticoids. It´s important to understand that stress leukogram takes time to occur. The variation on time depends on the animal species, although, in general, the glucocorticoides have a peak effects among 4 to 8 hours, which can last from 24 hours to 2 or 3 days

Uso de abraçadeira autoestática de náilon em intervenções cirúrgicas veterinárias

The wide variety of materials and auxiliaries both in hemostasis and in the use of several surgical techniques is in ascendancy. Many experimental studies have been done in order to reduce costs and surgical time, besides, provide less chance of infection during surgery. This paper aims to present a literature review about the use of nylon cable ties in major surgical procedures performed both in small and large animals

Laserterapia em lesões de coluna na Medicina Veterinária

Lasertherapy is a method of non-pharmacological treatment and surgery that can be used in several injuries and in various tissues, from bone fractures to tendonitis, skin wounds and damaged nerves, permitting the recovery of these structures and their functions without causing any side effects. Laser therapy aims to restore patients that suffered various injuries, such as bone fracture, inflammation, edema, tendon rupture, spinal cord injury, among others, without invasive intervention, and the results obtained in several studies and case reports have proven the high potential of this therapy to become an official treatment of various pathological changes

Escherichia coli O157:H7 como importante patógeno veiculado em produtos cárneos de origem bovina

Escherichia coli O157:H7 is a foodborne pathogen associated with enteritis in humans, ranging from a mild to bloody diarrhea to hemolytic uremic syndrome, thrombotic thrombocytopenic purpura and even death. Large E. coli O157:H7 outbreaks have been reported worldwide and are frequently associated with consumption of undercooked beef. Cattle are a major reservoir of the pathogen, which is found in the intestinal tract of the animal. The carcasses can be contaminated with feces during the slaughter and production process. Ground beef remains the most common vehicle. The purpose of this study was to determine the E. coli O157:H7 importance associated to human illness and productivity losses to the meat industry, as well as identifying mechanisms of contamination related to beef and strategies to improve the safety of beef products

Hiperadrenocorticismo atípico em cães

The endocrine diseases, notably Cushing's disease, are of great importance from the morbid pictures that affect the canine species. Due to the imprecision of the standard tests, the HAC can be a diagnosis difficult to confirm. Often, the clinical manifestations and biochemical and hematological findings support the diagnosis of HAC, but endocrine tests are normal or inconclusive. The excessive production of ACTH may, in the adrenals, not only stimulate the increase of glucocorticoids, but also of sex hormones. In recent studies, the concentrations of sex hormones were used as parameters to check the adrenal gland function in animals with suspected Cushing's disease, suggesting that high serum concentrations of 17 hydroxyprogesterone (17OHP) and other sex steroid hormones would be the cause of the so called atypical hyperadrenocorticism