Função da leptina no controle ventilatório: efeito central da leptina ou do antagonista do receptor melanocortina na resposta cardiovascular e na resposta ventilatória do CO2

A leptina é um hormônio protéico produzido por adipócitos que atua no sistema nervoso central (SNC) modulando as respostas metabólicas e cardiorrespiratórias. Estudos prévios demonstraram que a leptina ativa receptores do sistema melanocortina (MC3/4R) para modular a ingestão de alimentos e a atividade simpática, no entanto a função dos MC3/4R no controle ventilatório ainda não foi completamente elucidada. Dessa forma, o objetivo do estudo foi de avaliar a função do sistema melanocortina e da leptina sobre as respostas cardiovasculares, metabólicas e ventilatórias. Foram utilizados ratos Holtzman (n=6/grupo) implantados com cânula guia no ventrículo lateral (VL) para a administração de leptina (5 μg/3 μl/dia), de SHU9119, antagonista MC3/4R (0,6 nmol/3 μl/dia) ou do tratamento combinado (SHU+LEP) durante sete dias consecutivos. Após o sexta dia de tratamento, foram analisadas a resposta ventilatória (VE) durante a ativação do quimiorreflexo por hipercapnia (7% CO2) pelo método de pletismografia e o índice metalóbico pela análise do consumo de O2 e da produção de CO2 pelo método de calorimetria indireta. A pressão arterial media (PAM) e a frequência cardíaca (FC) foram avaliadas no sétimo dia de tratamento por meio de catéter intravenoso. A leptina injetada no VL reduziu a ingestão alimentar (~70%) e o peso corporal (~17%), promoveu um aumento no volume corrente (12±0.4 ml.kg-1, ...

Avaliação dos processos de alocação sexual do parasitóide Apanteles galleriae (Hymenoptera: Braconidae) em Galleria mellonella (Lepidoptera: Pyralidae) em função do tempo de fecundação

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Simulação de produção de sedimentos em microbacias em função de cenários de restauração florestal

In São Paulo state, deforestation and agriculture activities are increasing soil losses processes, especially in areas of susceptible soils where properties not adopt soil conservation practices. Environmental adequacy at property level regarding Permanent Protection Areas and Legal Reserves is considered a factor on reducing soil losses and considering that we assessed soil losses of different scenario of environmental adequacy. Simulations of erosive process were carried out in 15 catchments of Corumbataí river basin, according to different forest restoration scenarios, as well as the current situation of land use/land cover. The scenarios include the implementation of Permanent Preservation Areas (PPA), the reforestation of variable source areas, and two scenarios, the Legal Reserve installation in 20% of each catchment, being one of them for most critical areas in terms of erosion and the other at random. It was observed that the establishment of PPA and the reforestation of hydrologically sensitive areas, offered only a small contribution to the control of the erosive process, resulting in a reduction of 10% and 7,8%, respectively, while the legal reserve in critical areas has a significant reduction of 69,8%. The random scenario, in turn, resulted in a reduction of only 21,4%. Results show that reforestation could reduce soil losses, but previous studies of land prioritization and planning could increase significantly its efficiency at this process.

Efeitos da atividade física sobre equilíbrio, risco de quedas e função cognitiva de idosos com demência de Alzheimer: Salma Stéphany Soleman Hernandez. -

The Alzheimer’s dementia represents a clinical condition inherent to many chronic and neurodegenerative diseases that are usually related to a decline in the cognitive and physical functions. The objective of this experimental design research was to analyze the effects of a regular and systemized physical activity program over the cognitive functions, balance and risk of falls of elderly with Alzheimer’s Dementia (DA). The sample was made of 16 elderly with DA, distributed in two groups: a) intervention group – GI (9 subjects that had participated in a program of physical activity, that consisted of 3 weekly sessions of 60 minutes each, in alternated days and with a duration of 6 months); b) control group – GC (7 subjects that did not participate in the program of physical activity). Both groups maintained the doctoral and pharmacological assistance routine. The subjects passed through two different evaluations (pre and post-intervention) the questionnaire (Mini-exam of Mental State for cognitive functions) and motor tests (Berg Functional Balance Scale – EEFB, Timed Up-and-Go (TUG) time (TUGs) and steps (TUGp) and the test of agility and dynamic balance (AGILEQ) of the American Alliance for Health, Physical Education Recreation and Dance for elderly). The obtained results were, respectively in the pre and post-intervention moments: a) AGILEQ (GI = 39,1 ± 10,2 and 38,4 ± 8,9 and GC = 45,6 ± 16,7 and 59,9 ± 22,0 seconds) with the statistically interaction significant (ANOVA two-way; F1,14 = 32,07; p=0,01) between groups and moments; b) TUGs (GI = 9,8 ± 2,5 and 9,5 ± 3,3 and GC = 10,6 ± 4,5 and 12,7 ± 7,3 seconds) the test UMann Whitney did not appoint any significant differences between the groups in the post-intervention moment, however the analyzes of Wilcoxon evidenced a ...(Complete abstract click electronic access below)

Tubo digestório de Urostreptus atrobunneus (Diplopoda): estrutura e função

Millipedes are macro-arthropods of soil which perform a important role in maintaining the balance of the ecosystem, since they feed on decaying organic matter and because they promotes the soil enrichment, aeration and humidification. These animals are usually found in humid with low light places, under rocks and trunks. The diplopods exoskeleton is much resistant and impregnated with calcium salts. Due the secretion of defense, with strong and unpleasant smell, the animals of this class have few or no predators. Large diplopods populations are not observed, but explosions population can occur for unbalances enviromnmental, by climate change and by use of pesticides that may eliminate potential competitors. In this sense, the millipede Urostreptus atrobrunneus Pierozzi & Fontanetti, 2006, has presented points of infestation in urban centers of Sao Paulo state, causing many disorders of the human population. Because it is a newly described species, little is known of its aspects biological and morphological. Thus, the purpose of this study was to describe the structure and function of the digestive tract of the species U. atrobrunneus by means of histological, histochemistry and ultrastructural techniques. The results demonstrated that the digestive tract of U. atrobrunneus is similar to the descriptions given for other species. The foregut consists of a simple epithelium, composed of cells of different heights, covered by a cuticular intima, leaning on a thin basal membrane, followed by a well-developed muscular layer and an external membrane, around the foregut have a pair of salivary glands. The midgut epithelium has a pseudostratified, supported by a thick basal membrane, followed by a muscular layer and a layer of hepatic cells. The muscle is distributed unevenly coated with an external membrane, this portion is marked by the absence of cuticular intima... (Complete abstract click electronic access below)

Desempenho em tarefas computacionais em função do uso de diferentes periféricos

With the popularization of information technology and government incentives for inclusion in the digital era, an important issue for science and for industry is the design of tool s for entrance of input to the device, that is , the peripherals at tached to the computer that are reaching the consumer. In order to minimize the impact of repetitive use of these tools for entry, whether when playing games or working, more studies are in need to developper ipherals that enable comfort and effi ciency. This study examined the per formance of individuals with differents izes of hand (i.e., large and small ) in performance of three task s on the computer us ing mouses of small and large sizes. For thi s study, 19 young adul ts were volunteers and asked to per form activities with greater precision and speed. In addition, al l participants were asked on the use of computers. The results showed no statistically significant differences in the performance related to the size of the mouse between subjects with small and large hands. However, an interest ingresult as observed with respect to the performance of individuals with a large hand to perform tas ks more quickly. The results of this study suggest that with both, the small and the large mouse, individuals with big hands have a fas terper formancein tasks of dragging and clicking when compared with the performance of indi viduals with small hand.

Produtividade e sólidos solúveis da melancia irrigada em função de doses de nitrogênio

Pós-graduação em Agronomia (Produção Vegetal) - FCAV

Diferentes maneiras de definir a função logarítmica natural

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

As orações subordinadas substantivas em função de sujeito: questões de ensino

This paper attempts to answer how the descriptive analysis of the substantive subordination clauses made within the realm of academic research can contribute to the effective teaching of those structures in the Elementary School. After showing how the subordination has been treated in grammar school and textbooks and pointing at some recurring problems in the presentation of the subject, we present the treatment of subordinate clauses with the function of subject in two descriptive grammars of Portuguese, in order to ascertain to what extent the relevant aspects of the description of those clauses are related to the traditional way of teaching. From those descriptive works, we selected some functional features considered to be essential for the treatment of the subject in the Elementary School.

Orações substantivas em função de sujeito e de objeto nas fases arcaica e moderna do português

Neste artigo descrevemos o comportamento de orações subjetivas e objetivas diretas nas fases arcaica (séculos XIII a XV) e moderna (séculos XVI e XVII) do português. Adotamos o quadro teórico da gramaticalização e dessentencialização de orações e discutimos resultados para os parâmetros tipo semântico do predicado matriz, unidade semântico funcional representada pela oração encaixada e formato da oração encaixada. Observamos, ao longo das sincronias, correlações sistemáticas entre os parâmetros investigados para os dois tipos oracionais. Orações subjetivas apresentam menor variedade de padrões do que orações completivas objetivas, principal diferença a interferir em suas estabilidades sintático-semânticas nos períodos investigados.

Estudo para correção dos sensores da rede de monitoramento do campo elétrico em função do campo elétrico de tempo bom

A monitoring network of atmospheric electric field covering the Vale do Paraiba region was implemented. The sensors were located on different sites with different altitude and geographic topology. The present work reports the study carried on those sensors in order to verify the necessity of using some correction factor to the measured local electric field intensity due to effects of local environment. The measurements were done in continuous 24 hours per day with the data recorded on registers in each device accumulating information during a period of four months. The relation between the electric field values by each sensor was compared to the reference located on Sao Jose dos Campos city using the same period. In a graphical analysis using the local field intensity and the reference, the data were fitted to a straight line obtained by minimum square method. Variation up to 95% was observed between the field values in some sensors. Another method was proposed, comparing the mean values of the electric field in a function of time. The variation in some sensors reached up to 133%. We conclude that the variations are due to local atmospheric conditions and no correction factor is required on the electric field sensors

O Trickster na escola: um estudo sobre a função educativa do mito

Pós-graduação em Educação Escolar - FCLAR

Avaliação da prevalência das doenças peri-implantares e do sucesso e sobrevivência de implantes osseointegrados com 8 a 10 anos de função

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Interferência do parecoxibe sobre a função renal e lesão de rins submetidos ao estresse isquêmico: trabalho experimental em ratos com uso de NGAL como marcador da função renal

Pós-graduação em Anestesiologia - FMB