60 resultados para ras
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Pós-graduação em Biociências e Biotecnologia Aplicadas à Farmácia - FCFAR
Análise dos atendimentos do SAMU 192: componente móvel da Rede de Atenção às Urgências e Emergências
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Pós-graduação em Enfermagem (mestrado profissional) - FMB
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Pós-graduação em Engenharia Civil - FEIS
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Evidences suggest a role of renin-angiotensin system (RAS) in the development of chronic allograft injury. We correlated intrarenal angiotensin-converting enzyme, angiotensin II (Angio II) and transforming growth factor β1 (TGFβ1) expression in 58 biopsies-proven chronic allograft nephropathy (CAN) with tissue injury and allograft survival. The biopsies with CAN were graded according to Banff classification as I (22 cases), II (17) and III (19); 27 biopsies also showed a mononuclear inflammatory infiltrate in scarred areas. There were increased expression of angiotensin converting-enzyme (ACE), Angio II and TGFβ1 mainly in tubulointerstitial compartment in the group with CAN; there was no association of Angio II and TGFβ1 expression with interstitial fibrosis. There were no significant differences of ACE, Angio II and TGFβ1 expression between the patients treated and untreated with RAS blockade, and with the graft outcome. Interstitial inflammatory infiltrate had positive correlation with interstitial fibrosis and significant impact on graft survival at 8 years. Our study showed in a group of cases with CAN a high percentage of inflammatory infiltrate that correlated with interstitial fibrosis and graft outcome. The chronic inflammatory changes in these cases did not show significant association with local RAS expression.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Currently has few studies today concerning the behavior of the ethyl alcohol hydrated combustible in the geological environment, results of eventual spill or leaks in a wide transport chain and distribution. This work discusses the results of an experiment in laboratorial scale, that involves the monitoring of alterations in physical properties a simulate leak of alcohol in a tank with sand saturated in water, during 4920 hours. Are applied electrical resistivity, induced polarization and spontaneous potential geophysical methods. The electric resistivity is clearly correlating to the ethanol degradation pattern. The chargeability demonstrated sensibility to this pattern, while the natural electric potential revealed direct association with the oscillations of groundwater level. The variability of the physical parameters monitoring probable control for ethanol degradation process in environment study.
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The geophysical methods may be employed in aquifer system studies, as determination of groundwater level, soil/rock contact, beyond estimative of the aquifer thickness horizon. The geoeletric methods are particularly relevant in evaluations of the oilfields systems, due to directs relations between porosity and electrical resistivity, which allow inferences about oil and gas production. The indirect estimative of the productions in free aquifers system is something complex before of the diverse variables responsible for factors or physical phenomena, as clays minerals, which conditioned the physical parameters by electric geophysical methods. This paper present analyzed correlation among electrical resistivity, chargeability and direct measure flow in shallow wells, for determination of statistical relationships between parameters and evaluation of the geological constraints evolved. The study count with the 23 shallow wells located in free aquifer, constituted by alteration materials of the granites localized in Caçapava do Sul (RS). The geophysical data are acquired by vertical electric sounding in Schlumberger array. The correlations between electrical resistivity and flow, chargeability and flow, thickness of the soil/saprolite and flow indicated relationships between physical and hydrogeologic parameters, with variations conditioned by factors as porosity, permeability, besides intrinsic geological heterogeneities such soil variable thickness and rock fragments with several alteration degrees.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)