Avaliação clínica do crescimento gengival em pacientes sob terapia com nifedipina

Pós-graduação em Odontologia - FOAR

Estudo clínico e radiográfico do nível da crista óssea alveolar em pacientes fumantes

Pós-graduação em Biopatologia Bucal - ICT

Comparação entre sutura e cola de fibrina derivada do veneno de serpente para fixação de enxerto de tecido conjuntivo na correção de recessões teciduais marginais

Pós-graduação em Bases Gerais da Cirurgia - FMB

Fatores associados com a experiência de cárie em crianças de 4 e de 6 anos de idade atendidas em um programa educativo-preventivo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação da correlação entre peroxidação lipídica e o perfil de marcadores inflamatórios em pacientes com Diabetes mellitus tipo 2, dislipidemia e periodontite crônica

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Avaliação do efeito do laser de Er:YAG no tratamento da doença periodontal crônica em humanos: análises clínica, imunológica e microbiológica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeito do tratamento periodontal não-cirúrgico em pacientes portadores de Diabetes mellitus tipo 2 com doença periodontal: análises clínica, enzimática e microbiológica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação clínica e microbiológica periodontal de crianças e adolescentes sob terapia ortodôntica com aparelhos fixos ou removíveis

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeitos do controle da placa supragengival na doença periodontal crônica. Avaliação clínica, imunológica e microbiológica

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Leukotoxicity of Aggregatibacter actinomycetemcomitans in generalized aggressive periodontitis in Brazilians and their family members

Objective: The purpose of this study was to examine the leukotoxin promoter types of Aggregatibacter actinomycetemcomitans clones in subjects with generalized aggressive periodontitis (GAgP) and in their family members (FM). Material and Methods: Thirty-five patients with GAgP (33.9+/-7.1 years), 33 of their FM (22.8+/-11.4 years), and 41 patients with chronic periodontitis (CP) (44.1+/-9.4 years) were clinically analyzed using the plaque index, gingival index, probing depth (PD), and clinical attachment level (CAL). Subgingival biofilm samples were collected from four interproximal periodontal sites (>PD and >CAL) of each patient. The presence of A. actinomycetemcomitans and its leukotoxic clone was confirmed by polymerase chain reaction (PCR). Results: A. actinomycetemcomitans was observed in 23 (51.1%) GAgP patients and 16 (30.1%) CP patients. Thirty-seven (94.8%) patients showed minimally leukotoxic strains and 2 (5.1%) showed highly leukotoxic strains. In the FM group, 10 (30.3%) had aggressive periodontitis (AgP), 12 (36.3%) had CP, 11 (33.3%) were periodontally healthy or had gingivitis, and 12.2% were A. actinomycetemcomitans positive. Greater full mouth PD and CAL were observed in GAgP patients positive for the bacteria than those negative for it (p<0.05), and the presence of A. actinomycetemcomitans positively correlated with GAgP (Odds ratio, 3.1; confidence interval, 1.4-7.0; p=0.009). Conclusions: The presence of A. actinomycetemcomitans was associated with the clinical condition of GAgP, with most patients exhibiting a generalized form of the disease and minimally leukotoxic clones. Most of the relatives of GAgP patients presented either CP or AgP.

Longitudinal effect of curcumin-photodynamic antimicrobial chemotherapy in adolescents during fixed orthodontic treatment: a single-blind randomized clinical trial study

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Clinical assessment of nifedipine-induced gingival overgrowth in a group of brazilian patients

Although it has been established that nifedipine is associated with gingival overgrowth (GO), there is little information on the prevalence and severity of this condition in the Brazilian population. The aim of this study was to assess the occurrence of nifedipine-induced GO in Brazilian patients and the risk factors associated using a Clinical Index for Drug Induced Gingival Overgrowth (Clinical Index DIGO). The study was carried out on 35 patients under treatment with nifedipine (test group) and 35 patients without treatment (control group). Variables such as demographic (age, gender), pharmacological (dose, time of use), periodontal (plaque index, gingival index, probing depth, clinical insertion level, and bleeding on probing), and GO were assessed. Statistical analysis showed no association between GO and demographic or pharmacological variables. However, there was an association between GO and periodontal variables, except for plaque index. According to our study, the Clinical Index DIGO can be used as a parameter to evaluate GO. Therefore, we conclude that the presence of gingival inflammation was the main risk factor for the occurrence of nifedipine-induced GO.

Associação da raspagem com antibioticoterapia em um caso de periodontite agressiva generalizada

The treatment of aggressive periodontitis is a challenge to the clinician, therefore the search for effective treatment protocols of this disease is important. The aim of this case report was demonstrate the effectiveness of the combination of systemic antibiotics with non-surgical periodontal therapy in the treatment of generalized aggressive periodontitis. a 27-year-old patient (RCS), smoker for 11 years (10 cigarettes/day on average), with no systemic alteration, attended the periodontal clinic with a complaint abnormal dental position. After the clinical examination, the diagnosis of generalized aggressive periodontitis was defined. The non-surgical periodontal treatment was executed associated with administration of amoxicillin plus metronidazole for ten days. Clinical parameters (Clinical Attachment level, marginal gingival level, periodontal probing depth, bleeding on probing, plaque index and gingival index) and radiographic parameters (distance between the cemento-enamel junction and the bone crest) were evaluated before and after non-surgical periodontal treatment, after antibiotic therapy and three, six and 12 months after the treatment. After one year follow-up, the results showed improvement in clinical and radiographic parameters with stabilized and decreased tooth mobility and absence of tooth loss. It was concluded that the association of non-surgical periodontal therapy with the administration of amoxicillin/metronidazole was effective in the treatment of generalized aggressive periodontitis.

Avaliação das alterações no nível da crista óssea e na estabilidade de implantes em função instalados na região anterior da maxila enxertada com osso autógeno ou rhBMP-2

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Contribuição ao estudo das relações dos conectores maiores de próteses parciais removíveis com tecidos gengivais

The effect in the gingival tissue of four distinctive types of relationships between the major conector and the gingival margin was investigated in eight subjects in association with the experimental gingivitis model. The subjects wore appliances constructed in acrylic resin (retained by means of embrasure hooks) throughout the day an night, except during meals. After the appliances had been placed, the subjects were abstained from any oral hygiene for twenty-one days. Records of the Plaque Index, Gingival Index and probing deplh were taken at baseline and at each week. Data showed that there was a small increase in the Plaque Index and Gingival Index for the four areas and that the degree of inflammation of the covered areas was higher in the area without relief