O gênero masculino e a arte de cuidar de si mesmo

Vários estudos comparativos entre os sexos masculino e feminino comprovaram o fato de que o primeiro é mais vulnerável às doenças, sobretudo às enfermidades graves e crônicas e que morre mais precocemente. A despeito da maior vulnerabilidade e das altas taxas de morbimortalidade, os homens não buscam, como as mulheres, os serviços de atenção básica. O presente estudo buscou compreender como os homens freqüentadores de uma Unidade Básica de Saúde (UBS) se comportam em relação aos cuidados com a sua saúde. Foi realizado em um Centro de Saúde Escola (CSE), Unidade Auxiliar de uma Universidade de uma cidade do interior do Estado de São Paulo, inserido na rede Municipal de Saúde do município. Trata-se de uma pesquisa descritiva, qualitativa e quantitativa. A organização dos dados qualitativos foi baseada na Análise de Discurso do Sujeito Coletivo (DSC), sendo que a obtenção dos discursos ocorreu através de uma entrevista semi-estruturada. Na parte qualitativa, a constituição da amostra foi por conveniência e foram selecionados 15 sujeitos do gênero masculino, maiores de 18 anos, que compareceram na UBS para um atendimento eventual ou para um atendimento pré-agendado. Na parte quantitativa, a constituição da amostra foi ao acaso, sendo sorteados 459 prontuários de usuários do sexo masculino, com 18 anos ou mais, que foram atendidos no período de Janeiro a Dezembro de 2009 para serem analisados através da estatística descritiva. Além disso, foram utilizadas as planilhas referentes às campanhas de vacinação contra a Gripe Pandêmica (H1N1) e Gripe Sazonal (Influenza) para a obtenção do número dos usuários do sexo masculino, de 20 anos ou mais, que participaram dessas campanhas no período de Janeiro a Julho de 2010. Em relação aos dados de caracterização dos indivíduos da amostra selecionada observamos que a faixa etária foi de 50 a 59 ano... (Resumo completo, clicar acesso eletrônico abaixo)

Estudo do método Monte Carlo e sua aplicação no modelo SIR

In this work we present a discussion and the results of the simulation of disease spread using the Monte Carlo method. The dissemination model is the SIR model and presents as main characteristic the disease evolution among individuals of the population subdivided into three groups: susceptible (S), infected (I) and recovered (R). The technique used is based on the introduction of transition probabilities S-> I and I->R to do the spread of the disease, they are governed by a Poisson distribution. The simulation of the spread of disease was based on the randomness introduced, taking into account two basic parameters of the model, the power of infection and average time of the disease. Considering appropriate values of these parameters, the results are presented graphically and analysis of these results gives information on a group of individuals react to the changes of these parameters and what are the chances of a disease becoming a pandemic

MxA interacts with and is modified by the SUMOylation machinery

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Methicillin resistance in Staphylococcus aureus and coagulase-negative staphylococci: Epidemiological and molecular aspects

Infections caused by the genus Staphylococcus are of great importance for human health. Staphylococcus species are divided into coagulase-positive staphylococci, represented by S. aureus, a pathogen that can cause infections of the skin and other organs in immunocompetent patients, and coagulase-negative staphylococci (CNS) which comprise different species normally involved in infectious processes in immunocompromised patients or patients using catheters. Oxacillin has been one of the main drugs used for the treatment of staphylococcal infections; however, a large number of S. aureus and CNS isolates of nosocomial origin are resistant to this drug. Methicillin resistance is encoded by the mecA gene which is inserted in the SCCmec cassette. This cassette is a mobile genetic element consisting of five different types and several subtypes. Oxacillin-resistant strains are detected by phenotypic and genotypic methods. Epidemiologically, methicillin-resistant S. aureus strains can be divided into five large pandemic clones, called Brazilian, Hungarian, Iberian, New York/Japan and Pediatric. The objective of the present review was to discuss aspects of resistance, epidemiology, genetics and detection of oxacillin resistance in Staphylococcus spp., since these microorganisms are increasingly more frequent in Brazil.

Clinical and laboratory description of a series of cases of acute viral myositis

Describe the clinical and laboratory profile, follow-up, and outcome of a series of cases of acute viral myositis. A retrospective analysis of suspected cases under observation in the emergency department was performed, including outpatient follow-up with the recording of respiratory infection and musculoskeletal symptoms, measurement of muscle enzymes, creatine phosphokinase (CPK), lactate dehydrogenase (LDH), transaminases (AST and ALT), blood count, C-reactive protein, and erythrocyte sedimentation rate in the acute phase and during follow-up until normalization. Between 2000 and 2009, 42 suspected cases were identified and 35 (27 boys) were included. The median age was 7 years and the diagnosis was reported in 89% in the first emergency visit. The observed respiratory symptoms were cough (31%), rhinorrhea (23%), and fever (63%), with a mean duration of 4.3 days. Musculoskeletal symptoms were localized pain in the calves (80%), limited ambulation (57%), gait abnormality (40%), and muscle weakness in the lower limbs (71%), with a mean duration of 3.6 days. There was significant increase in CPK enzymes (5507±9180U/L), LDH (827±598U/L), and AST (199±245U/L), with a tendency to leukopenia (4590±1420) leukocytes/mm(3). The complete recovery of laboratory parameters was observed in 30 days (median), and laboratory and clinical recurrence was documented in one case after 10 months. Typical symptoms with increased muscle enzymes after diagnosis of influenza and self-limited course of the disease were the clues to the diagnosis. The increase in muscle enzymes indicate transient myotropic activity related to seasonal influenza, which should be considered, regardless of the viral identification, possibly associated with influenza virus or other respiratory viruses.

Ecos da memória: a re-construção da identidade em A misteriosa chama da rainha Loana, de Umberto Eco

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

La Casa Nel Vicolo: um romance de Maria Messina à moda do “feuilleton”

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)