Moda e literatura: a poética do vestuário em Macedo e Alencar

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Devir - criança da matemática: experiências educativas infantis imagéticas

Pós-graduação em Educação Matemática - IGCE

Entre palavras e imagens: o acontecimento de 11 de setembro nas revistas Veja e Carta Capital : a arquitetura do imaginário social sobre o terrorismo

Pós-graduação em Educação - IBRC

A escrita para percussão dos compositores do Grupo Música Nova: a busca pelo novo analisada a partir da notação

Pós-graduação em Música - IA

Articulações territoriais: uma cartografia da atenção à população em situação de rua

Pós-graduação em Psicologia - FCLAS

Stability study of darunavir ethanolate tablets applying a new stability-indicating HPLC method

Chemical and physical degradation of drugs may result in altered therapeutic efficacy and even toxic effects. Therefore, the aim of this work was to study the stability of darunavir and to develop and validate a liquid chromatography (LC) method to determine darunavir in raw material and tablets in the presence of degradation products. The novel method showed to be linear from 6.0 to 21.0 μg/mL, with high precision (CV < 2%) and accuracy (recuperation of 99.64%). It is simple and reliable, free of placebo interferences. The robustness of the method was evaluated by a factorial design using seven different parameters. Forced degradation study was done under alkaline, acidic, and oxidative stress at ambient temperature and by heating. The LC method was able to quantify and separate darunavir and its degradation products. Darunavir showed to be unstable under alkaline, acid, and oxidative conditions. The novelty of this study is understanding the factors that affect darunavir ethanolate stability in tablets, which is the first step to unravel the path to know the degradation products. The novel stability-indicating method can be used to monitor the drug and the main degradation products in low concentrations in which there is linearity.

Environmental Innovation: in search of a meaning

The purpose of this paper is to propose a definition of the term “green/environmental innovation”, based on a systematic literature review. Design/methodology/approach– The literature review conducted in this research was based on papers published in ISI Web of Science and Scopus databases. Findings– Environmental innovations are organizational implementations and changes focusing on the environment, with implications for companies’ products, manufacturing processes and marketing, with different degrees of novelty. They can be merely incremental improvements that intensify the performance of something that already exists, or radical ones that promote something completely unprecedented, where the main objective is to reduce the company's environmental impacts. In addition, environmental innovation has a bilateral relationship with the level of proactive environmental management adopted by companies. Increasing of environmental innovation tends to come up against many barriers.

A/r/tografia de um corpo-experiência: arte contemporânea, feminismos e produção de subjetividade

Pós-graduação em Psicologia - FCLAS

Equações diferenciais implícitas com descontinuidade

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Relações entre o global e o local: circulação e uso de referências de moda por grupos de baixa renda

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Metodologias de Inovação: Soluções da TRIZ aplicadas em um ambiente design thinking

This work discusses the theories of TRIZ and Design Thinking, as well as the association of the two theories by a tool for the application of TRIZ in a Design Thinking environment. This work proposes the association of the theories by an easy and systematic method constituted by a step by step process. The objective of this work is to create a method that facilitates the application of the two innovation theories helping the inventors to develop new products without the necessity of being creative people. By the end of the work is shown the research case accomplished as an empirical analysis of this tool that can be a fast and efficient method to solve inventive problems focused in the expectations and necessities of the clients