Identificação dos princípios ativos antiulcerogênicos das folhas de Casearia sylvestris: contribuição para o desenvolvimento de um fitoterápico

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Uso sustentável de biodiversidade brasileira - prospecção químico-farmacológica em plantas superiores: Alchornea glandulosa, Alchornea triplinervia (Euphorbiaceae), Indigofera truxillensis e Indigofera suffruticosa (Fabaceae)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo de aspectos químicos, biológicos e biossintéticos em Piper fuligineum Kunth(Piperaceae)

Pós-graduação em Química - IQ

Crucial surviving aspects for vitrified in vitro-produced bovine embryos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Forskolin effect on the cryosurvival of in vitro-produced bovine embryos in the presence or absence of fetal calf serum

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Preservation of wild feline semen by freeze-drying: experimental model

According to the Convention on International Trade in Endangered Species, 36 wild feline species are threatened by extinction or severely endangered, and to save them is the target of several conservation programs. This study aimed to assess the viability of the freeze-drying technique for domestic cat sperm cells, with the ultimate goal of transferring this technology to the wild feline species. The domestic cat is an excellent experimental model for wild felids. It is in this scenario that the freeze-drying process (low-temperature vacuum dehydration) of sperm cells shows its value in preserving male cats' germplasm. Results from membrane and DNA integrity analysis are promising and validates the use of frozen-dried sperm samples in intracytoplasmic sperm injections (ICSIs). Further studies are still necessary to evaluate the ICSI embryo production using domestic cat frozen-dried sperm and the possibility of using such technology with wild felines.

Levantamento da mastofauna terrestre de médio e grande porte em remanescente de floresta neotropical – Itatinga, SP

The Brazil´s Atlantic coastal forest biome is considered one of the richest and most exuberant biodiversity of the whole planet. Still, other data shows the reality of this Brazilian forest: more than 93% of its original formation has been already devastated, being the human actions the greatest threat to the perpetuation of the balance and diversity of this ecosystem. This destruction affects all the fauna and flora, with even greater impact on medium and large mammals, due to its high demand on the availability of resources, living area and sensitivity to disturbances. However, today it is known the vital importance of these mammals in the preservation and maintenance of biological systems. Thus, the purpose of this study was to survey the species richness of medium and large mammals in a remnant neotropical forest located in Itatinga, SP,Brazil, using the indirect method of recording (traces on sand-plots, marking territorial, faeces, carcasses, scratches on tree trunks and vocalizations) and camera trapping. Data were collected during ten (10) consecutive months in the year 2008, from February to November. Within twenty-five plots of sand installed and monitored during the ten months were found fifteen (15) species of terrestrial mammals of medium and large, five (5) orders and twelve (12) families. Among them, we highlight the presence of threated species like the puma (Puma concolor), the deer (Mazama gouazoubira) and the giant anteaters (Myrmecophaga tridactyla). The chosen method showed up effective in raising terrestrial mammalian species of medium and large neotropical forest area, having a good applicability and advantages over other existing methods. The study area presents a huge diversity of species and, therefore, this work it is recommended to be only the beginning of new researches in the area in order to enrich... (Complete abstract click electronic access below)

Estudo sobre as unidades de medidas das grandezas físicas básicas: comprimento, massa e tempo

Measurement units are used almost automatically nowadays, but few people know the origin of the units of length (meter), mass (kilogram) and time (second). And do not care to know what were anciently units of which our ancestors used, the difficulties that existed to make a set of measures. The aim of this work is to make a historical approach, through various units of measure. They are old, unusual to others that have been forgotten since the standardization of meters, and is also discussed about the metric system Englih (Once and foot), AV system (eg pound grain) that are still used in some countries like United States and England, the Troy system consisting of units of measure for precious stones and metals (eg gold and diamond) are also cited some physical concepts as reference: inertial, non-inertial; mass: gravity, relativistic, inertial

Desenvolvimento e avaliação das atividades antioxidante e despigmentante in vitro de emulsões múltiplas a/o/a contendo dipalmitato kójico

Currently, there has been a growing concern for men and women with the appearance of the face and body, driven primarily by aesthetic standards set by the media. For this, the pharmaceutical and cosmetic industries have conducted numerous research projects aiming at the development of formulations that mitigate the aging and some skin disorders such as hipercromies. One of the most frequent pathologies of skin is melasma, a manifestation of hyperpigmentation caused by hipermelanogenesis symmetrical and progressive, caused usually by hormonal irregularities, exposure to sunlight and genetic factors. In addition to sunscreen, the treatment is indicated the use of depigmenting substances, among them the kojic dipalmitate (DK), which is cleaved into kojic acid (5- hydroxy-2-hydroxy-methyl-4H-piran-4-one) by esterase after absorption by the skin cells. The kojic acid inhibits the action of tyrosinase as a chelator of ions and promotes the reduction of eumelanin and its precursor monomer. To promote a controlled release and improve the stability of the system, the DK can be incorporated into multiple emulsions, that is, complex systems composed of two emulsifications, where the two types of emulsions (W/O and O/W or O/W and W/O) exist simultaneously, forming emulsions of type W/O/W or O/W/O. This work aimed to incorporate the DK in emulsion W/O/W, physical-chemical systems obtained and to evaluate the antioxidant and depigmenting action in vitro of the developed formulations. The physico-chemical characterization was performed by microscopic analysis, quantification and size distribution, determination of pH, conductivity, zeta potential and bioadhesive test of the formulations. The droplet size in accordance with the use of light microscopy and dynamic light scattering is approximately 1μm. The pH, electrical conductivity and bioadhesion have not changed with the addition... (Complete abstract click electronic access below)

Mamíferos de Médio e Grande Porte de Uma RPPN No Município de Jaú, Estado de São Paulo

The medium to large-sized mammals make population control of invertebrates and vertebrates, as well as seed dispersers are also important. Are losing territory and living area because of deforestation and fragmentation of natural areas, mainly in the Atlantic Forest. The RPPN Amadeu Botelho, in the municipality of Jaú, São Paulo State, is one of the last forest remnants of interior paulista. It is isolated from other forest fragments and thus is a wildlife refuge in the region of Jaú, Midwest of the State. Animals as Pumas (Puma concolor), ocelot (Leopardus pardalis), cat-Moorish (Puma yagouaroundi), have already been sighted in the reserve by officials and residents. The buffer property of the farm Santo Antônio dos Ipês, is surrounded by several plantations, and is very close to the Centre of the city of Jaú. In addition to the lifting of the reservation, it sized mammal species diagnosed the influences that the activities of the farm and the proximity to the Centre of the municipality of Jaú exert to fauna studied

Levantamento da mastofauna terrestre de médio e grande porte ao longo da Rodovia Alcides Soares, Botucatu-SP, como subsídio para ações de conservação

Atropelamentos associados à fragmentação dos habitats naturais, tanto para construção de estradas, quanto para agricultura, são uma das principais causas de mortalidade para várias espécies de animais silvestres pelo mundo todo. Durante o período de agosto de 2011 e junho de 2012, em um trecho da Estrada Vicinal Alcides Rodrigues Soares do município de Botucatu, interior do estado de SP, foi realizado o levantamento de mamíferos terrestres de médio e grande porte através do método de parcelas de areia e transecto, além da procura de carcaça de animais atropelados. Espécies como Onça-parda (Puma concolor) e Tamanduá-bandeira (Myrmecophaga tridactyla), ambas em situação vulnerável de extinção, foram registradas em proximidade da estrada. Através dos dados obtidos, tem se como objetivo demonstrar a importância da valorização da fauna local, com a construção de passagens de fauna, como uma das medidas para a sua conservação e consequente redução dos diversos distúrbios e impactos causados por estradas

Qualidade de vida do trabalhador de enfermagem de um hospital Estadual

The search for quality of life (QOL) is now an ideal among thousands of people worldwide and is currently the subject has been studied in different areas of knowledge. Thus, one can perceive it in different dimensions, each with its due importance to people's lives. The verification of quality indexes of work life (QWL) may provide information on factors that directly interfere with the satisfaction and personal motivation and collective, with reflections on the structure and excellent service. To this end, we carried out a study to know the characacteristics of quality of life of nursing professionals in a state hospital in São Paulo State, based on short range of quality of life of the World Health Organization (WHOQOL-BREF). This work is a study with a quantitative approach, cross-sectional descriptive and exploratory data analysis using descriptive statistics, involving a sample of 281 nurses who answered the scale for measuring quality of life, composed of four areas: physical, psychological, social relationships and environment. In the study, these areas were related to the professional position, and shift work. There was a satisfactory quality of life in the study population in different areas of WHOQOL-BREF. There was no statistically significant changes in quality of life among the variables. It follows that the population presented data consistent with an adequate quality of life, thus making relevant to addressing the quality of life of nursing in a healthcare organization which has as fundamental to the pursuit of quality through the accreditation process second hospital established by the National Accreditation Organization (ONA) that aims at establishing and implementing a process of improving health care, thereby stimulating the services to achieve higher standards of quality