66 resultados para epilepsia com pontas multifocais independentes
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Pós-graduação em Agronomia (Entomologia Agrícola) - FCAV
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Pós-graduação em Agronomia (Produção Vegetal) - FCAV
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The present study aimed to evaluate the droplet spectrum of hydraulic nozzles, under different pressures and spray liquid compositions, using a laser particle size analyzer. In a completely randomized design, two air induction twin flat-fan nozzles (AD-IA/D 11002 and AD-IA/D11004) and two hollow-cone nozzles (MAG - 2 and MAG - 4) were evaluated, in factorial design 3 x 2: tree spray pressures (207, 276 and 345 kPa for twin flat-fan nozzles, and 414, 483 and 552 kPa for cone nozzles); and two spray liquid compositions (water and water plus phosphatydilcoline + propionic acid adjuvant). The addition of adjuvant reduced the volume median diameter for the AD-IA/D 11002 and 11004 nozzles; however it had an opposite effect with the MAG - 4 nozzles and not changed with the MAG - 2 nozzles. In adverse weather conditions, it is not recommended the use of hollow cone spray nozzle, even with the addition of adjuvant tested because of the high risk potential of drift.
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This paper investigates, in light of the theory of Functional Discourse Grammar (HENGEVELD; MACKENZIE, 2008), the concessive clause that is not subordinated to other clauses, i.e., it has no semantic or syntactic relations with clauses before or after it, and which we call Independent Concessive. The aim is to describe the discursive properties and the semantic, morphosyntactic and prosodic structure of this type of clause, showing that its relevance is in the construction and organization of discourse. The results indicate that the Independent Concessive works in speech as a parenthesis which interrupts the discursive course and is then highlighted by a special prosodic contour, combined with the presence of Interactive Acts. It is therefore a Move, the highest layer of the Interpersonal Level, the level that relates to the pragmatic aspects of the grammar of a language. The universe of research used is the Iboruna corpus, a database that records a variety of Portuguese from the Northwest of São Paulo.
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Pós-graduação em Agronomia (Energia na Agricultura) - FCA
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Pós-graduação em Ciência dos Materiais - FEIS
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Seizure is a clinical manifestation of abnormal neuronal hyperactivity of the cerebral cortex, presentation clinical varies according to the location and extent of the brain. The classic seizure begins with an inicial period, named prodrome, followed by the aura, the ictus and finally the post-ictus phase. Seizures can be generalized or focal/partial types. Focal seizures with secondary generalization are the most common type in dogs. The seizure can be divided etiologically in intracraneal (idiopathic epilepsy; sintomatic; probably sintomatic epilepsy) and extracraneal disorders. After determining the etiology of seizures and critical analysis of the frequency, severity, and worry they cause to the owner, you should make the decision whether to launch an anticonvulsant drug therapy. Although the ideal is the elimination of seizures, the real goal should be to decrease the frequency and intensity of crises, without affecting the quality of life of patients taking the drugs used side effects acceptable. The veterinary should consider the bioavailability of the drug, contraindications, toxicity, drug interactions, the amount of daily administration, the availability of the owner and the cost of therapy. Seizures can be controlled in about 70- 80% of the dogs and in the majority of the cats when treated with Phenobarbital alone. Addition of a second drug (usually potassium bromide), decreases the number of seizures in more that 50% in about 70-80% of dogs. However, approximately 20-30% of dogs are refractory to this treatment. In these cases, it will be necessary to think in other pharmacological alternatives, like felbamate, gabapentin, levetiracetam, zonisamid, among others. It has been concluded that... (Complete abstract click eletronic access below)
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A epilepsia do lobo temporal (ELT) é a principal forma de epilepsia, e a principal lesão desenvolvida por pacientes com ELT é a esclerose mesial temporal (EMT) apresentando perda neuronal, gliose e atrofia da região do hipocampo. Os íons cálcio são fundamentais para o funcionamento de inúmeras vias metabólicas em todos os níveis fisiológicos e desempenham papel fundamental nas respostas de despolarização neuronal. Foi comprovado que a ativação tanto de receptores ionotrópicos quanto metabotrópicos de glutamato promove o influxo anormal de Ca2+ para o meio intracelular, potencializando o efeito de excitação associado à EMT. O cálcio atua tanto como mensageiro celular secundário, quanto primário através da interação com um receptor específico na superfície celular, o Receptor Sensor de Cálcio (CASR). O CASR é expresso em diversas regiões do cérebro, incluindo o hipocampo, no entanto são desconhecidas muitas das possíveis funções desempenhadas por este receptor no cérebro. Ele pertence à família de receptores acoplados a proteína-G, e exibe homologia significativa com os receptores metabotrópicos de glutamato (mGluRs). Ademais, os mGluRs regulam a expressão da família de proteínas ligantes de cálcio neuronal, da qual faz parte a proteína VILIP-1, associada especificamente com o fenômeno da plasticidade sináptica no cérebro. O objetivo deste projeto foi determinar a expressão das proteínas CASR, mGluR1 e VILIP-1 em tecidos de hipocampo de pacientes com epilepsia do lobo temporal comparando com a expressão de tecidos de indivíduos normais. Os três genes encontraram-se subexpressos nos tecidos de pacientes com ELT, sendo que os tecidos dos pacientes, em grau crônico da doença, justificam tais graus de expressão. Sugere-se uma possível interação entre CASR e mGluR1 e...(Resumo completo, clicar acesso eletrônico abaixo)
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This work presents a proposal to replace thetraditional system of traction electric car that usesone electric motor and a mechanical differential, by two electric motors of lower power, controlled byelectronic control low cost. The proposed control isopen loop and uses the technique of Pulse WidthModulation (PWM), discrete and synchronizedaiming to reduce the generation of harmonics. The implementation of two smaller motor one on each wheel-drive distributes the weight of the vehicle, improving the heat exchange of the windings,beyond enable the power components supporting a current of 50% predicted for only one motor . The solution adopted for being open-loop, has a similar behavior to the mechanical differential, where theeffort imposed by the trajectory makes the velocity distribution between the wheels be appropriate tovehicle trajectory
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Epilepsy is a chronic disorder that impairs life quality (LQ) and interferes in emotional, personal, social and family relationship aspects. This study evaluated 165 people with epilepsy diagnosis, ranging from 18 to 75 years old (M=41,28; SD= 13,26), by means of the QQV-65 (Life Quality Questionnaire with 65 questions) and investigated the association between the questionnaire scores and the disease features, comparing patients who showed refrectory seizures with patients with partially controled seizures. There was no difference in relation to the two groups regarding the LQ factor. The QQV-65 emotional factor was the most affected in both groups, since the estimated mean z-escore was 51,0±14,4 for Group I and 49,9±14,7 for Group II. Regarding the type of crisis, the analysis of variance (ANOVA) revealed that Health was the only factor in QQV-65 that showed a statistically significant difference between the z-scores (P = 0.024). However, for the frequency of epileptic seizures, except Health (P = 0.185), other factors QQV-65 proved to be related in a statistically significant way (P> 0.05). The research demonstrated that seizure control perception is quite important in the evaluation of life quality in all its aspects (health, body, society, emotion, locus of control, self-concept and cognition).
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Pós-graduação em Saúde Coletiva - FMB
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Over the last few years, new technologies have been developed to making cavity preparations, among which the diamond burs CVDentus® (CVDentus, São José dos Campos, Brazil) are outstanding. These points are produced by chemical deposition from the vapor phase, forming a single diamond stone, with greater durability than the conventional diamond burs. Coupled to the ultrasound appliance, they have several clinical applications in Dentistry with advantages over conventional rotary instruments, such as lower pressure, noise, vibration and heat, as well as reducing the need to use local anesthesia, contributing to minimize patient’s fear and anxiety. The aim of this study was to present the complete restorative dental treatment performed with this system in a child patient with a prior history of non-cooperative behavior. The use of this new technology offered the patient greater comfort, making it possible recondition the patient’s attitude to dental treatment, in addition to favoring conservative cavity preparations to be made.
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A epilepsia é a doença neurológica maiscomum em seres humanos e cães, possui diversas etiologias e é classificada em epilepsia primária, idiopática ou hereditária e epilepsia secundária ou adquirida. A maioria dos cães epiléticos é tratada com fármacos antiepiléticos padrões, fenobarbital e/ou brometo de potássio, com os quais obtém-se sucesso; porém, cerca de 20-30% dos cães tratados necessitam de terapia adicional, pois não respondem a terapia padrão. Os medicamentos utilizados como anticonvulsivantes levam a efeitos de toxicidade e menos de 50% dos cães com epilepsia permanecem livres de convulsões sem efeitos secundários das medicações. Novas alternativas terapêuticas têm sido utilizadas. Dentre elas, a Gabapentina que é um medicamento análogo ao GABA e possui diferentes mecanismos de ação, tem efeito dose-dependente, absorção saturada, não tem ligação às proteínas plasmáticas e, ao contrário da maioria das medicações anticonvulsivas, possui eliminação renal. Quando sua eficácia é comprovada em associação às drogas anticonvulsivas padrões, é possível a redução da dose das mesmas evitando ou minimizando assim os desagradáveis efeitos secundários destas medicações. Por esses motivos, o objetivo desse trabalho é averiguar a eficácia da Gabapentina quando associada aos fármacos padrões utilizados na terapia antiepilética. Para tanto, foi realizado um levantamento bibliográfico em cinco bases de dados eletrônicos. Foram obtidos 13 artigos, os quais, após serem analisados, permitiram concluir que a Gabapentina apresenta resultados significativamente satisfatórios no tratamento da epilepsia idiopática em cães refratários ao tratamento padrão; porém, mais estudos em cães não devem ser descartados de modo a melhor elucidar esses efeitos
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)