Apoptosis in T lymphocytes from spleen tissue and peripheral blood of L. (L.) chagasi naturally infected dogs

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A espacialização da fala no cinema

O artigo parte de uma simples constatação: é bastante insatisfatória, no presente estágio da pesquisa, a colocação do problema das relações entre imagens e palavras no universo fílmico. Trata-se, no entanto, de uma questão decisiva para a estética do cinema. em geral, as análises feitas valorizam apenas a função das imagens na gênese e no desenvolvimento das significações. A hipótese de trabalho que se apresenta aqui, vem propor, ao contrário, uma abordagem do complexo sígnico constituído pela fusão indissolúvel dos dois recursos expressivos, que forma assim um meio de comunicação específico, original e absolutamente novo. Esse caráter inédito exige uma investigação minuciosa e urgente, conjugando-se perspectivas filosóficas, semióticas e propriamente cinematográficas.

Paulo Emílio Salles Gomes: a compreensão da realidade brasileira através da crítica de cinema

O objetivo deste artigo é compreender o papel intelectual desempenhado por Paulo Emilio Salles Gomes na sociedade brasileira. Partindo da análise da sua crítica de cinema no jornal O Estado de São Paulo, nos anos 1950, busco caracterizar o processo de construção do empenho político e cultural voltado para a construção de uma sociedade democrática no Brasil, que se desdobrava nas análises sobre o cinema, e a realidade brasileira nas décadas de 1960 e 1970.

Hadronic physics in peripheral heavy Ion collisions

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

RESONANCE PRODUCTION IN PERIPHERAL HEAVY-ION COLLISIONS

Heavy-ion collisions at ultrarelativistic energies may be used as a powerful source of photons and pomerons. We compute the rates for pseudoscalar meson production through two-photon and two-pomeron scattering, at energies that will be available at RHIC and LHC. Light mesons will mostly be produced by pomeron fusion at large rates, the two processes are comparable for charmed mesons, while electromagnetic production will be dominant for bottom mesons. We discuss the possibility of observing the reaction gammagamma(PP) --> R --> gammagamma, and comment on the particular case where R could be a scalar resonance at 650 MeV.

Genetic damage in human peripheral lymphocytes exposed to antimicrobial endodontic agents

Objective. Formocresol, paramonochlorophenol, or calcium hydroxide have been widely used in dental practice to eradicate bacteria and consequently to produce root canal disinfection. Taking into consideration strong evidence for a relationship between DNA damage and carcinogenesis, the purpose of the present study was to evaluate the genotoxic effects of antimicrobial endodontic compounds in human peripheral lymphocytes by single-cell gel ( comet) assay. This technique detects DNA strand breaks in individual cells.Study design. A total of 10 mu L of the tested substance solution (formocreso1, paramonochlorofeno1, and calcium hydroxide at 100-mu g/mL concentration) was added to human peripheral lymphocytes from 10 volunteers for 1 hour at 37 degrees C. The negative control group was treated with vehicle control (PBS) for 1 hour at 37 degrees C, as well. For the positive control group, lymphocytes were exposed to hydrogen peroxide at 100 mu M during 5 minutes on ice.Results. No DNA breakage was detected after a treatment of peripheral lymphocytes by formocresol, paramonochlorophenol, or calcium hydroxide at 100 mu g/mL.Conclusions. In summary, our results indicate that exposure to formocresol, paramonochlorophenol, or calcium hydroxide may not be a factor that increases the level of DNA lesions in human peripheral lymphocytes as detected by single-cell gel (comet) assay.

Brain versus peripheral angiotensin II receptors in hypovolaemia: Behavioural and cardiovascular implications

1. Angiotensin (Ang)II is involved in responses to hypovolaemia, such as sodium appetite and increase in blood pressure, Target areas subserving these responses for AngII include the cardiovascular system in the periphery and the circumventricular organs in the brain.2. Conflicting data have been reported for the role of systemic versus brain AngII in the mediation of sodium appetite.3. The role for systemic AngII and systemic AngII receptors in the control of blood pressure in hypovolaemia is well established. In contrast with systemic injections, i.c.v injections of AngII non-peptide AT(1) and AT(2) receptor antagonists, such as losartan and PD123319, do not reduce arterial pressure in sodium-depleted (furosemide injection plus removal of ambient sodium for 24 h) rats. Thus, brain AngII receptors are likely not important for cardiovascular responses to hypovolaemia induced by sodium depletion.4. Intracerebroventricular injections of losartan or PD 123319 increase arterial pressure when injected at relatively high doses. This hypertensive effect is unlikely to be an agonist effect on brain AngII receptors, Increases in arterial pressure produced by i.c.v, losartan are attenuated by lesions of the tissue surrounding the anterior third ventricle (AV3V). The hypertensive effect of i.c.v, AngII is abolished by lesions of the AV3V.5. Hypertension induced by AngII receptor antagonists is consistent with hypotension induced by AngII acting in the brain, However, the full physiological significance of this hypotensive effect mediated by brain AngII receptors remains to be determined.

Nuclear coherent versus incoherent effects in peripheral RHI collisions

We derive simple and physically transparent expressions for the contribution of the strong interaction to one-nucleon-removal processes in peripheral relativistic heavy-ion collisions. The coherent contribution, i.e., the excitation of a giant dipole resonance via meson exchange, is shown to be negligible as well as the interference between Coulomb and nuclear excitation. The incoherent nucleon-knockout contribution is also derived suggesting the nature of the nuclear interaction in this class of processes. We also justify the simple formulae used to fit the data of the E814 Collaboration. © 1995 Elseier Science B.V. All rights reserved.