On a regular convex solver potential for an elastic-damage constitutive model: a theoretical analysis

This work is related with the proposition of a so-called regular or convex solver potential to be used in numerical simulations involving a certain class of constitutive elastic-damage models. All the mathematical aspects involved are based on convex analysis, which is employed aiming a consistent variational formulation of the potential and its conjugate one. It is shown that the constitutive relations for the class of damage models here considered can be derived from the solver potentials by means of sub-differentials sets. The optimality conditions of the resulting minimisation problem represent in particular a linear complementarity problem. Finally, a simple example is present in order to illustrate the possible integration errors that can be generated when finite step analysis is performed. (C) 2003 Elsevier Ltd. All rights reserved.

Discriminating new physics scenarios at the Next Linear Collider: The role of polarization

We explore the potential of the Next Linear Collider, operating in the e γ mode, to disentangle new physics scenarios in single W production. We study the effects related to the exchange of composite fermions in the reaction e γ→Wνe, and compare them with those arising from trilinear gauge boson anomalous couplings. We stress the role played by the initial state polarization to increase the reach of this machine and to discriminate the possible origin of the new phenomena.

Tests of anomalous quartic couplings at the Next Linear Collider

We analyze the potential of the Next Linear e+e- Collider to study anomalous quartic vector-boson interactions through the processes e+e-→W+W-Z and ZZZ. In the framework of SU(2)L⊗U(1)Y chiral Lagrangians, we examine all effective operators of order p4 that lead to four-gauge-boson interactions but do not induce anomalous trilinear vertices. In our analysis, we take into account the decay of the vector bosons to fermions and evaluate the efficiency in their reconstruction. We obtain the bounds that can be placed on the anomalous quartic interactions and we study the strategies to distinguish the possible couplings.

Vibrational-rotational structure of supersingular plus Coulomb potential A/r4 - Z/r*

The vibrational-rotational states of the supersingular plus Coulomb potential A/r4 - Z/r are variationally constructed using a nonorthogonal basis of atomic hydrogenic eigenfunctions modulated by an exponential factor exp(- α/r), ensuring the correct behavior in the vicinity of the supersingularity. The construction is carried out in two successive stages. The first stage is restricted to trial functions without radial nodes, leading to a variational optimization of the parameters of the basis for each value of the angular momentum. The second stage uses the complete basis to construct linear trial functions and to formulate the variational problem in terms of secular equations, yielding the successive vibrational and rotational states. Numerical results for the corresponding energy levels are presented for different combinations of the intensity parameters of the potential. © 2001 Plenum Publishing Corporation.

Direct signals for large extra dimensions in the production of fermion pairs at linear colliders

We analyze the potential of the next generation of e+e- linear colliders to search for large extra dimensions via the production of fermion pairs in association with Kaluza-Klein gravitons (G), i.e., e+e- →ff̃G. This process leads to a final state exhibiting a significant amount of missing energy in addition to acoplanar lepton or jet pairs. We study in detail this reaction using the full tree level contributions due to the graviton emission and the standard model backgrounds. After choosing the cuts to enhance the signal, we show that a linear collider with a center-of-mass energy of 500 GeV will be able to probe quantum gravity scales from 0.96 (0.86) up to 4.1 (3.3) TeV at a 2 (5)σ level, depending on the number of extra dimensions. ©2001 The American Physical Society.

Voltammetric behavior of nitrofurazone and its hydroxymethyl prodrug with potential anti-chagas activity

Chagas' disease is a serious health problem for Latin America. The situation is worsened by the lack of efficient chemotherapy. The two available commercial drugs, benznidazole and nifurtimox, are more effective in the acute phase of the disease. Nitrofurazone is active against Trypanosoma cruzi, however its high toxicity precludes its current use in parasitosis. Hydroxymethylnitrofurazone is a prodrug of nitrofurazone. It is more active against Trypanosoma cruzi than nitrofurazone, besides being less toxic. This work shows the voltammetric behavior of nitrofurazone and a comparison with those of metronidazole and chloramphenicol using cyclic, linear sweep and differential pulse voltammetries. For these drugs also the prediction of the diffusion coefficients using Wilke-Chang equation was performed. The reduction of nitrofurazone is pH-dependent and in acidic medium the hydroxylamine derivative, involving four electrons, is the principal product formed. In aqueous-alkaline medium and with a glassy carbon electrode pre-treatment the reduction of nitrofurazone occurs in two steps, the first involving one electron to form the nitro-radical anion and the second corresponding to the hydroxylamine derivative formation. Hydroxymethylnitrofurazone presented the same voltammetric behavior and electroactivity, indicating that the molecular modification performed in nitrofurazone did not change its capacity to be reduced. A brief discussion regarding the differences in biological activity between the two compounds is also presented. ©2005 Sociedade Brasileira de Química.

Modelo de tomada de decisão integrando teoria das restrições, programação linear e simulação: estudo de caso numa Indústria Siderúrgica

Pós-graduação em Engenharia Mecânica - FEG

Vidros óxidos contendo átomos pesados para aplicações em óptica não linear e fotônica na região do infravermelho

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Análise linear e espacial entre alguns atributos produtivos e tecnológicos da cana- de-açúcar com o pH de um argissolo vermelho de Suzanápolis (SP)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Quantization of unstable linear scalar fields in static spacetimes

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Controle de dissociação molecular com ferramentas de dinâmica não linear

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Equação de Schrödinger não linear com coeficientes modulados

Pós-graduação em Física - FEG

Ribifolin, an orbitide from jatropha ribifolia, and its potential antimalarial activity

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Therapeutic potential of mesenchymal stem cells to treat Achilles tendon injuries

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Physico-chemical characterization and analytical development for sodium azumolene, a potential drug designed to fight malignant hyperthermia

Sodium azumolene is a drug designed to fight Malignant Hyperthermia (MH), which is characterized by genetic predisposition and triggered by the use of inhalational anesthetics. This drug is shown as a water-soluble analogue of dantrolene sodium, 30-folds more water soluble, which gives advantages for its emergency use. To our knowledge there is no analytical method for sodium zaumolene raw material or dosage form published so far. The objective of the present investigation was to develop and validate analytical methods to achieve sodium azumolene chemical identification and quantification. The sodium azumolene was characterized regarding its thermal behavior, by differential thermal analysis and thermogravimetric analysis; Visible, UV and infrared absorption. To accurately assess the sodium Azumolene content three different analytical methods (visible and UV spectrophotometry and high performance liquid chromatography) were developed and validated. All methods showed to be linear, accurate, precise and reliable. Azumolene has shown to be equipotent to dantrolene in the treatment and prevention of an MH crisis and the great advantage compared to dantrolene is better water solubility. This study has characterized the sodium azumolene and presents new analytical methods which have not been reported so far.