84 resultados para Driving while impaired by alcohol


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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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The aim of this study was to verify if α-tocopherol, the main substance of Vitamin E and also the one with the major antioxidant propriety, could offer citoprotection to a stomach damaged by alcohol. There are many forms of α-tocopherol, two forms of them were evaluated; d-l-α-tocopherol, the synthetic form and d-α-tocopherol, the natural form of α-tocopherol. Three experiments were made, all of them having absolute ethanol as the lesion agent, but the period and the doses changed in each of them. In the first two experiments, each group of animals received a different form of α-tocopherol and in the third experiment, they’ve received α-tocopherol p.o. for the period of seven days before the lesion agent was administrated. Moreover, immunohistochemistry assays were made from the stomachs samples of the third experiment to verify possible mechanisms involving nitric oxide and 2-cyclooxygenase. Satisfactory results of citoprotection have been obtained when the two forms were administered in the period of one week at doses of 100 mg/kg for synthetic form and 150 mg/kg for natural type. Nevertheless, the two forms didn’t differ statistically in their effectiveness against ethanol. The immunohistochemistry assays showed an increase of the levels of NO and COX2 in relation with the negative control, although there was no correlation between this increase and the gastroprotective effect. In conclusion, α-tocopherol has gastroprotection effect in some doses, but apparently there is no such a thing like the better the dose, the better the effect; that citoprotection don’t have a relationship with NO neither with COX2; the natural and the synthetic form don’t differ in their gastroprotection effect. More studies must be done looking forward an effective dose and also to understand the mechanisms underlay the citoprotection of α-tocopherol in the stomach

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Burns are frequent accidents, and they are among the major causes of morbidity and mortality in our society. In Brazil, statistical data on such lesions are relatively scarce, and they are concentrated in a few treatment centers. Data on such accidents allow for specific care to be timely and properly taken in order to provide patients with a better prognosis, in addition to enabling the development of prevention programs as well as fire-prevention safety laws. To characterize the epidemiological profile of users at the Burn Treatment Unit of Bauru State Hospital. Collection of epidemiological data through the e-pront system and from charts of burned inpatients from April 2005 to April 2010. During the studied period, 906 hospitalizations of burned patients occurred, with an annual average of 181.2 individuals. Their mean age was 28.4 years, with a predominance of males. The mean hospitalization period was of 27.6 days, with a median of 16 days and a maximum of 216 days; 14.7% developed to death, with the highest mortality rate in the first two weeks of hospitalization. Second-degree burns were the most frequent; 36.8% of the patients burned less than 10% of their body surface, and there was a gradual frequency reduction when a larger burned surface was taken into account; the greater the affected areas, the higher the number of deaths; 91% resulted from thermal agents, 6% from electric and 2% from chemical agents; scalding was the major cause among all agents, followed by alcohol associated with fire and direct flame. The major area affected areas were the upper limbs. The study shows the need for educational and preventive measures, particularly for the young adult population, by means of educational programs and prevention campaigns

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The aim of this paper is to present some considerations on discursive positions that challenge the textual production of a student from Cycle II Elementary School. We intend to show how a biased reading of the student’s text might not observe significant textual features and disregard the student’s level of literacy, thus ignoring the insertion of this writing in a socio-historical context. Such an approach, while defined by ideology, is determined by the pedagogical discourse that focuses on formal patterns of language, which prevents the teacher from identifying rich and interesting linguistic and textual procedures in the text in question, indicative of the student's literacy and his/her potential for authorship. This reading mostly denies the efforts that have been made to reverse the exclusion of public schools students, weakening the idealist discourse that claims for a “school for everybody”.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Reservoirs are artificial environments built by humans, and the impacts of these environments are not completely known. Retention time and high nutrient availability in the water increases the eutrophic level. Eutrophication is directly correlated to primary productivity by phytoplankton. These organisms have an important role in the environment. However, high concentrations of determined species can lead to public health problems. Species of cyanobacteria produce toxins that in determined concentrations can cause serious diseases in the liver and nervous system, which could lead to death. Phytoplankton has photoactive pigments that can be used to identify these toxins. Thus, remote sensing data is a viable alternative for mapping these pigments, and consequently, the trophic. Chlorophyll-a (Chl-a) is present in all phytoplankton species. Therefore, the aim of this work was to evaluate the performance of images of the sensor Operational Land Imager (OLI) onboard the Landsat-8 satellite in determining Chl-a concentrations and estimating the trophic level in a tropical reservoir. Empirical models were fitted using data from two field surveys conducted in May and October 2014 (Austral Autumn and Austral Spring, respectively). Models were applied in a temporal series of OLI images from May 2013 to October 2014. The estimated Chl-a concentration was used to classify the trophic level from a trophic state index that adopted the concentration of this pigment-like parameter. The models of Chl-a concentration showed reasonable results, but their performance was likely impaired by the atmospheric correction. Consequently, the trophic level classification also did not obtain better results.

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Pós-graduação em Enfermagem (mestrado profissional) - FMB

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Ciência e Tecnologia Animal - FEIS

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Pós-graduação em Enfermagem (mestrado profissional) - FMB