Propriedades de tranporte, caos e dissipação num sistema dinâmico não linear

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Outono em uma organização: convivendo com as crises

Pós-graduação em Psicologia - FCLAS

Light and temperature induce variations in the density and ultrastructure of the secretory spaces in the diesel-tree (Copaifera langsdorffii Desf.-Leguminosae)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Cidadania e práticas escolares: as representações de um grupo de alunos do ensino médio de uma escola pública paulista

Pós-graduação em Educação Escolar - FCLAR

Next-generation sequencing reveals large connected networks of intra-host HCV variants

Background: Next-generation sequencing (NGS) allows for sampling numerous viral variants from infected patients. This provides a novel opportunity to represent and study the mutational landscape of Hepatitis C Virus (HCV) within a single host.Results: Intra-host variants of the HCV E1/E2 region were extensively sampled from 58 chronically infected patients. After NGS error correction, the average number of reads and variants obtained from each sample were 3202 and 464, respectively. The distance between each pair of variants was calculated and networks were created for each patient, where each node is a variant and two nodes are connected by a link if the nucleotide distance between them is 1. The work focused on large components having > 5% of all reads, which in average account for 93.7% of all reads found in a patient. The distance between any two variants calculated over the component correlated strongly with nucleotide distances (r = 0.9499; p = 0.0001), a better correlation than the one obtained with Neighbour-Joining trees (r = 0.7624; p = 0.0001). In each patient, components were well separated, with the average distance between (6.53%) being 10 times greater than within each component (0.68%). The ratio of nonsynonymous to synonymous changes was calculated and some patients (6.9%) showed a mixture of networks under strong negative and positive selection. All components were robust to in silico stochastic sampling; even after randomly removing 85% of all reads, the largest connected component in the new subsample still involved 82.4% of remaining nodes. In vitro sampling showed that 93.02% of components present in the original sample were also found in experimental replicas, with 81.6% of reads found in both. When syringe-sharing transmission events were simulated, 91.2% of all simulated transmission events seeded all components present in the source.Conclusions: Most intra-host variants are organized into distinct single-mutation components that are: well separated from each other, represent genetic distances between viral variants, robust to sampling, reproducible and likely seeded during transmission events. Facilitated by NGS, large components offer a novel evolutionary framework for genetic analysis of intra-host viral populations and understanding transmission, immune escape and drug resistance.

Um direcionamento às novas tecnologias na arquitetura: habitação de um futuro presente, em um espaço para a vida

This paper tries, across research, books, magazines and charts that relate to the architecture of today, establishing a direction as to the technological advances that may be involved in the architecture project. Such that the configuration space has flexibility to meet the basic architectural principles and the wishes of the user, who should participate as a key character of the decisions of spatialization - interface. Both the personal point of view of their social relations within the housing, and the functional environments equipped and qualified to meet expectations during its use. Respecting the power of free choice of human beings, not to put yourself to the detriment by excessive use of technology. And still look for ways to integrate the individual to society connected to your network - home. Keywords: interface, information, technology, space flexibility

Etnicidade, conservação ambiental e direitos territoriais em áreas de incidência de programas de desenvolvimento social e sustentável

Ribeira Valley, a region covered by the last continues area of the Atlantic Rain Forest in São Paulo State, in Brazil, is thus a preservation law and environmental control target, is now configurated as locus where emerge conflicts concerning economic and agricultural activities, particularly in places where befall public policies recognizing territorial rights – quilombo remnants, indigenous lands and sustainable development settlings. The research’s aim is to understand, considering each of these contexts, if and how a conservationist focus is assumed as a value and a strategy, connected to etnicity and traditionality, in order to actualize these social spaces.

Diferença, dispersão e fragmentação socioespacial: explorações metropolitanas em Brasília e Curitiba = Différence, dispersion et fragmentation sociospatiale : explorations métropolitaines à Brasilia et Curitiba

Pós-graduação em Geografia - FCT

A universidade no contexto internacional: o relações públicas como mediador intercultural no projeto Brasil de Todo Mundo

The following dissertation aims to propose an institutional and intercultural projecy of reception and integration of foreign students from academic mobility programs for the campus unit of Bauru. Such action is necessary because of the absence of a reception program of these students, the reception and integration into the social and cultural reality of the place in which they live is a fundamental part of international experience. As an example for this institutional proposal, we discuss the extension of project experience Brasil de Todo Mundo, which aims to deepen the reflections on the Brazilian cultural universe for foreign students who are in Brazil over a period, while taking academic mobility in the Universidade Estadual Paulista, Bauru campus. Student leadership project, Brasil de Todo Mundo emerged from the international experience in mobility programs offered by UNESP, from students of campus Bauru, when in the back of their experiences, they realized that they could continue being tourists your own country with the reception of foreign students. In addition, the identification of expectations in social and intercultural skills, in addition to reasons connected with the increase academic and language skills are a form of very strong approach, which helps in creating intercultural dialogue spaces between the students, the main objective of the project

Generalized interval vector spaces and interval optimization

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Speleoclimate dynamics in Santana Cave (PETAR, S(a)over-tildeo Paulo State, Brazil): general characterization and implications for tourist management

Show caves provide tourists with the opportunity to have close contact with natural underground spaces. However, visitation to these places also creates a need for management measures, mainly the definition of tourist carrying capacity. The present work describes the results of climate monitoring and atmospheric profiling performed in Santana Cave (Alto Ribeira State and Tourist Park - PETAR, Brazil) between 2008 and 2011. Based on the results, distinct preliminary zones with different levels of thermal variation were identified, which classify Santana Cave as a warm trap. Two critical points along the tourist route (Cristo and Encontro Halls) were identified where the temperature of the locality increased by 1.3 degrees C when tourists were present. Air flow from the inner cave to the outside occurs during the austral summer, and the opposite flow occurs when the outside environment is colder than the air inside the cave during the austral winter. The temperature was used to establish thresholds to the tourist carrying capacity by computing the recovery time of the atmospheric conditions after the changes caused by the presence of tourists. This method suggests a maximum limit of approximately 350 visits per day to Santana Cave. The conclusion of the study is that Santana Cave has an atmosphere that is highly connected with the outside; daily variations in temperature and, to a lesser extent, in the relative humidity occur throughout the entire studied area of the cave. Therefore, the tourist carrying capacity in Santana Cave can be flexible and can be implemented based on the climate seasonality, the tourism demand and other management strategies.

Integrable deformations of strings on symmetric spaces

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Discrete quantum phase spaces and the mod N invariance

An extended Weyl-Wigner transformation which maps operators onto periodic discrete quantum phase space representatives is discussed in which a mod N invariance is explicitly implemented. The relevance of this invariance for the mapped expression of products of operators is discussed. © 1992.

A fotografia amadora e fotoclubista no Brasil e no México: trajetórias e conexões latino-americanas (1940-1950)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A organização dos espaços na educação infantil: possibilidades educativas na proposta Fazer em Cantos

Pós-graduação em Educação - FCT