Aproveitamento dos resíduos gerados pelo processamento industrial/artesanal de pedra-sabão da região de Ouro Preto

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Determinação da qualidade da radiografia digital aplicada às soldas de gasodutos e oleodutos terrestres e marítimos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeito da ciclagem mecânica em pré-molares restaurados com inlays confeccionados com diferentes materiais cerâmicos na resistência de união dentina-restauração

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Proposta de um modelo matemático para apoio às decisões táticas da gestão da produção

Pós-graduação em Engenharia Mecânica - FEG

Regulamentação Sanitária de Medicamentos

A regulamentação sanitária de medicamentos é uma das oito diretrizes da Política Nacional de Medicamentos. Trata-se da fiscalização e regulamentação de registro de medicamentos e da autorização de funcionamento desde os produtores até o varejo de medicamentos, bem como das restrições àqueles sujeitos a controle especial. A regulamentação sanitária de medicamentos tem como objetivo garantir eficácia, segurança, qualidade e custo aos produtos farmacêuticos. Os estudos clínicos dos medicamentos de Referência, a bioequivalência ou biodisponibilidade relativa e testes de equivalência dos medicamentos similares e genéricos são meios de avaliar a eficácia e a segurança. A qualidade é garantida lote a lote pelas Boas Práticas de Fabricação e Controle dos produtos farmacêuticos e a certificação da empresa pela ANVISA. O custo é avaliado pela câmara técnica de medicamento (CMED), que estabelece os critérios para fixação e ajuste de preços dos produtos farmacêuticos. No pós-registro, a efetividade, segurança e qualidade dos produtos são avaliadas por meio das comprovações exigidas na renovação do registro e, principalmente, pelo programa de farmacovigilância. Palavras-chave: Registro de Produtos. Medicamentos de Referência. Medicamentos Similares. Medicamentos Genéricos. Alteração de Registro de Produtos. ABSTRACT Health Regulations for Drugs The health regulation of drugs is one of eight guidelines issued within the National Drug Policy. It refers to the supervision and regulation of drug registration and the approval of operations, from the manufacturers to the retailers of medicines, as well as the restrictions that apply to drugs under special control. The health regulation of medicines is aimed at controlling the effectiveness, safety, quality and cost of pharmaceutical products. Clinical studies of brand-name (innovator) medicines, bioequivalence or relative bioavailability and the equivalence tests of generic and ‘similar’ brand-name drugs are means used to assess efficacy and safety. Quality is assured on a batch-to-batch basis by compliance with the Good Manufacturing Practices and Control of pharmaceutical products and by the certification of companies offered by ANVISA. The cost of a medicine is assessed by the Technical Chamber of Medicine (CMED), which establishes the criteria for setting and adjusting the prices of pharmaceutical products. After registration, the effectiveness, safety and quality of products are monitored by means of the tests required on renewal of registration and especially by the pharmacovigilance program. Keywords: Product Registration. Original Brand-name Drugs. Similar Drugs. Generic Drugs. Modification of Product Registration.

Imobilização de lipase po diferentes técnicas para obtenção de catalizadores estáveis

Pós-graduação em Biologia Geral e Aplicada - IBB

Simulação numérica através do método dos elementos finitos e comparação experimental para obtenção de tensões e deformações específicas em fêmur com prótese total de quadril

Pós-graduação em Engenharia Mecânica - FEG

Otimização do processo de MRP (Material Requirement Planning) de embalagens: uma aplicação da metodologia lean six sigma em uma indústria de agronegócios

There is a growing search for continuous improvement within the companies which creates an obligation of reducing and when it is possible eliminating waste. Production Planning and Control Department (PCP) is not out of this question, making necessary the application of methods and creation of tools that eliminate steps which do not add value to the planning process. This paper aims to develop a tool which concentrates in just one place all the necessary information to make the packaging material requirement planning (MRP) in a agribusiness company. Besides, it also aims, in a more visual way and using devices that prevent mistakes (Poka-Yoke), to reduce the number of reviews and mistakes made by analysts. As a result, an Excel spreadsheet was developed. This spreadsheet shows what happens with the status of planning and receiving of packaging, giving some advices when some critical situation happens. The use of Lean Manufacturing Method and the action research method helped to well define the problem and to reduce the number of steps, spreadsheets and time of process in 80%, 60% and 75%, respectively

Recuperação de resíduos plásticos provenientes dos processos de injeção

The competitiveness among global markets, the constant need for reducing manufacturing costs and also the growing environmental commitments are fueling the development of techniques for recovery residual parts generated by industrial processes. Among the various areas of a company, we highlight those that involve the processing of raw materials derived from oil, such as polymers (resins), which may take centuries to decompose in the environment and also present as a economic and environmentally strategic point. Thus, this study would examine the recovery of waste polypropylene, from the injection process of a major multinational in the field of home appliances through the recycling by a process comprising the milling, extrusion and chipping of waste material. Easy to deploy, this proposal aims to reduce levels negligible disposal (scrap) of these residues as well as the reintegration of the production process into pieces no visual and no structural importance, aimed at cutting costs and reducing environmental impacts caused. After the survey data in kilograms of waste material generated in a given period of time, and the study of changes in material properties, it would enable the reuse steadily in the injection process

Arranjo fisico na montagem com fluxo continuo nas superficies de comando composto

Based on the fierce competitiveness of manufacturing companies and the planning problems arising from the lack of flexibility and forecasting demand, companies are increasingly looking to reflect on the most appropriate methods to manage its manufacture. Today it is possible to obtain higher gains and lower costs through very efficient tools, this paper uses action-research to model and implement the physical layout of a manufacturing cell, with strong theoretical basement returned to Lean Production System and acting systematically in flexibility in mounting. Through observation and joint action of the observer and staff can report problems that occurred during the phases of planning and implementation of improvements. With the improvement of the physical arrangement in the assembly was possible to obtain significant gains by reducing the production cycle, the manpower required, spending of non-compliance and increasing productivity, final product quality and health in the workplace

Análise dinâmica e estrutural de virabrequim

This paper deals with static analysis and dynamic stress of an ensemble crank and crankshaft, contained within a combustion engine of 4 cylinders. Aimed to illustrate procedures for computer-aided analysis having as goal the optimization of components according to the need for the market demand. Thus, to work in static and dynamic analyzes were summarized the basic theory involved in the calculations and analyzes necessary actuation forces and held a brief introduction about the manufacturing process and forging. Subsequently, it was applied with the use of software in a case the crankshaft, to obtain the performance and structural dynamic thereof. There was a conservative result and critical points in the fillet of the crankshaft bearing, as well as for lubrication hole. It was concluded that there are possibilities for improvements in the manufacturing process and design optimization in order to provide lower criticality and a more robust part

Perfil econômico do lítio nos países sulamericanos e consumo mundial

The lithium industry has changed and the producers of lithium carbonate form South America play a dominant role in the world. This paper discusses the South American geological resources, production and producers of lithium considering the potential growth in lithium consumption for electric vehicle batteries. Taking into account the manufacturing companies and their external connections, their participation in corporate groups and the international market for the stocks of metal, in addition to facts and updates that affect this market and its key growth trends. This inventory of the most important reserves takes into account the geological context of the formation of these deposits, including a description of the types of deposits exploited in the world today. Besides the general description was made a brief description of the South American resources, more exploited by the media (Salar de Atacama, Salar de Hombre Muerto, Salar de Uyuni) and Pegmatites of Província Pegmatítica Oriental do Brasil and Província Seridó-Borborema).

Desenvolvimento de um equipamento para análise de desgastes em prótese de articulação total de quadril

Pós-graduação em Engenharia Mecânica - FEG

Estudo do comportamento em fadiga das ligas AA6005, AA6063 e AA6351

Aluminum alloys have shown great potential for the automotive industry, especially aluminum alloys 6xxx series. This category has good mechanical strength and excellent corrosion resistance, important for the areas of construction and transport. The automotive industry has always shown great interest in the study of fatigue behavior, because structural components are subjected to cyclic and vibration loads, generating cracks and fracturing. The mechanical response depends on the material properties, applications, surface condition and microstructure. In this work was study the fatigue behavior of high cycle of machined bodies (not polished) and the effect of roughness on the fatigue life for three aluminum alloys of 6xxx series: AA6005, AA6351 and AA606, all in the T6 condition . S / N curves were made from fatigue tests in rotating bending (R = -1). The influence of roughness was studied by measuring the roughness of each specimen. Was compare the fatigue behavior of polished specimen and not polished specimens. The fractured surfaces of samples were observed by MEV, and it was observed that most of nucleation sites for fatigue crack is initiated below the surface

Práticas de gestão da melhoria contínua e aprendizado e suas contribuições para a capacidade de inovação na indústria de construção naval do Brasil

After years of stagnation, the naval construction industry in Brazil has been experiencing a period of recovery caused by investments in the oil and gas sector and the implementation of governmental programs that aimed to regenerate it. However, efforts in learning and innovations are needed in order to reinsert the country in this activity and achieve international levels of competitiveness. Based on literature about learning processes and continuous improvement practices and their impact in the innovative and productive processes, this paper aims to identify the main tendencies, mechanisms and procedures to improve the construction and management processes in the Brazilian naval construction industry. The methodology used for the data analysis classifies obtained information from magazines and annals of congresses of the sector, according to the established analysis categories (phenomena). Such categories study information related to the productive and technological processes of the industry, the main internal and external relations of the industrial park, the management of resources and processes, policies, investments, etc. The data was collected in the period 2004-2010, and more than 500 registers that show a dominance of the investment phenomenon, especially in the increase of productive capacity, were catalogued. In addition to this, there is evidence of modernization in the manufacturing plan and the equipment, diverse forms of cooperation, implementation of human resources management practices and engineering or processes and products. Hence, a process of catching up governs and is guided by modernization and increase training in this industry.