Antimicrobial activity of six plant extracts from the brazilian savanna on periodontal pathogens

Fundação do Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Enterococcus spp. em espécimes clínicos de pacientes atendidos em unidades de terapia intensiva

The relationship between the occurrence of enterococci in the oral microbiota and serious infections in patients hospitalized in intensive care units (ICU) has been established. This study evaluated the presence of Enterococcus faecalis and other species of this genus in the mouths of patients on ICU, correlating it with oral and systemic conditions. Data on health and socioeconomic, medication use, medical and family history of patients maintained for 72 hours in the ICU, diagnosed with severe infection or who have developed this condition after the entry to the unit were obtained. Fifty patients provided intraoral and extraoral clinical samples for analysis (above and subgingival biofilm, saliva and buccal mucosa, followed by obtaining samples of respiratory secretions for patients with pneumonia, and blood and urine for sepsis). The presence of target microorganisms was performed by polymerase chain reaction (PCR) and culture using selective media. The chi-square and Mann-Whitney tests were used for statistical analysis, and the significance level was 5%. The intraoral clinical conditions of the patients showed poor. E. faecalis was significantly more frequent microorganism, followed by E. faecium. The use of broadspectrum antimicrobial action was associated with the presence of these opportunistic microorganisms. These bacteria were more frequent in patients with periodontitis or gingivitis. The results showed that enterococci associated with serious infectious processes may originate from resident microbiota of patients and its prevalence is not elevated in healthy individuals.

Determinação fenotípica das haptoglobinas em pacientes com dor crônica causadas por desordens temporomandibulares

The phenotypes of the hemoglobin-haptoglobin (HbHp) system were measured in 124 subjects, 100 patients with chronic pain in temporomandibular disorders and 24 normal, without any bodily pain during the years 2000 -2003. The system Hb-Hp showed polymorphism Hp1-1, Hp2-1 and Hp2-2, at 100% and 85% respectively; anahaptoglobinemia (Hp0) in 15% of the sample studied. Hp1-1 genotype was present significantly (p < 0, 0001) in patients with TMDs, regardless the clinical type TMD, suggesting that Hp1-1 and likely genetic marker of susceptibility for the development of chronic pain in TMD.

Estresse salino em plantas jovens de cana-deaçúcar: respostas bioquímicas e fisiológicas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação do potencial biológico de extratos hidroetanólicos de Astronium sp incorporados ou não em sistemas nanoestruturados: in vitro e in vivo: in vitro e in vivo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Mapeamento geológico-geotécnico pelo método de detalhamento progressivo: aplicação no planejamento e gestão de obras rodoviárias

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Carreadores lipídicos nanoestruturados para incorporação de complexos de cobre(ii) aplicáveis no estudo frente ao Mycobacterium tuberculosis

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Implicações geomorfológicas das alterações do escoamento superficial pela urbanização: análise dos processos erosivos na bacia hidrográfica do córrego Tucunzinho (São Pedro - SP)

This paper presents an evaluation of the geomorphological implications of urban runoff on the evolution of linear erosion processes in peri-urban areas. The Tucunzinho watershed (São Pedro/SP) case was chosen because it presents linear erosive forms in which the dynamic is associated with urban expansion into fragile areas and implantation of inadequate dissipation devices. The method proposed by the Soil Conservation Service (SCS) was adopted to obtain the Curve Number (CN) and runoff hydrographs of different sectors of the basin. The coverage classification (use and occupancy) was based on analysis of aerial photographs of two periods (1962 and 2006, updated in the field in 2011). The IPHS1 model was used for the simulation and analysis of the hydrological behavior for both the pre-urban occupation and the current occupation. The hydrogeomorphological analysis helped understand the influence of the urban run-off on the erosion dynamics, clearly showing the ineffectiveness of dissipation energy devices in the area, which has a natural susceptibility to erosion due to litho-soil characteristics.

Efeito do tirosol sobre biofilmes de Streptococcus mutans

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Processos geodinâmicos associados a mudanças de uso da terra: o caso da microbacia hidrográfica do Córrego Caçula (Ilha Solteira - SP)

Pós-graduação em Engenharia Civil - FEIS

Determinação do grau de risco a enchentes na bacia do Córrego Morumbi, município de Piracicaba-SP

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo da ação de derivados semi-sintéticos de curcumina em linhagens celulares de câncer humano

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Epidemiologia da colonização e infecção microbiana em Unidade de Terapia Intensiva Neonatal: abordagem clínica e molecular

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Perfil de citocinas do padrão Th1, Th2, Th17 e o estado redox de indivíduos com leishmaniose visceral pré e pós tratamento

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O gênero Eugenia: da química à farmacologia

Research on natural products is extremely important either for new compound discovery with possible pharmacology uses or for its impact on economy, which moves millions of dollars for year. Scientific studies related on utilization and characterization of bioactive substances are important due to the fact that many drugs currently used by the population were synthetized from isolated compounds of natural products. Among many medicinal species commonly used, there are that ones from the genus Eugenia, witch belongs to Myrtaceae family. Eugenia is one of the biggest genus from this family and has about 5000 species and Brazil has 400 of them, which are appreciated on gastronomy for its fruits, for example, pitanga (Eugenia uniflora), cherry (Eugenia involucrata), clove (Eugenia caryophyllata) and cagaita (Eugenia dysinterica). Phytochemical studies of plants from this genus report the presence of several secondary metabolites like flavonoids, tannins, coumarins, anthocyanins and more. Eugenia species have important pharmacology activity as antioxidant, hypothermic, antidiarrheal, antihypertensive, antimicrobial and fungicide. Thus, Eugenia is a genus which has species with potencial phytotherapic products