Obtenção e caracterização de suporte de regeneração óssea de dióxido de titânio

Due to complications caused by metallic implants in the replacement of bone tissue, the biological application of ceramics raised and became a viable alternative. The titania has the ability to promote bone tissue regeneration based on its structure, mechanical and biologically properties compatibility. The present work aims at obtaining and characterization of Titania (TiO2) porous ceramics produced by the polymeric sponge method (replica method). Polyurethane sponge with 10 ppi and 15 ppi (pores per linear inch) were used. The process differentiation is the air blower used to remove excess slurry. The ceramics sponges were dried in an oven, then pre-sintered at 1000 o C and sintered at 1450 o C. The effect of direct sintering at 1450 o C was also assessed. The percentage of solids used to prepare the slurry was 40 to 45% by weight. To increase the surface porosity of the sponge, 20% of starch was added. There was difficulty on controlling the thickness of the slurry layers on the sponge which resulted in the variation of samples mechanical resistance. Despite this, the results obtained are quite promising for the proposed use, indicating that it is possible to obtain titania sponges with an apparent porosity of around 60%, a bulk density ranging from 40 to 47% and a compressive strength resistance – that with better control of layers depositions – can vary from 1 to 4 MPa

Subluxação atlantoaxial canina

The atlantoaxial subluxation or luxation is an instability of this articulation that produces excessive flexion of this joint causing the cranial aspect of the axis to rotate dorsally into the vertebral channel with subsequent spinal cord compression. This disorder is most commonly found in young small breed dogs. The diagnosis of this disease is done by survey radiographs, where there is a larger distance between the atlas dorsal arch and the axis spinal process characterize the atlantoaxial subluxation. Surgical stabilization is the treatment of choice and multiple implants show the best results to stabilize the atlantoaxial joint. The main complications are sudden death or implant failure. The sudden death happens because of cardiorespiratory arrest and it is most likely caused by brainstem iatrogenic trauma. However, a larger study comparing different surgical stabilization techniques should be performed to evaluate relative success rates in dogs that have the same initial neurologic status

Utilização de gonadotropina coriônica equina em protocolos de inseminação artificial em tempo fixo em bovinos de corte

Current cattlemen must seek methods to maximum reproductive efficiency of their beef herds, making the business competitive and enhancing greater profitability. For the cow-calf producers, efficiency translates into more cows producing one calf every year. Fixed-time artificial insemination (TAI) is one of several technologies that producers utilize to reach this goal. Postpartum anestrus is one of the biggest obstacles to overcome in order to obtain suitable results at the end of the breeding season. The TAI protocols are efficient in re-establishing cyclicity in noncycling cows during the postpartum period, streamlining the use of labor on farms, allowing the use of artificial insemination (AI) on a large scale, and introducing superior genetics to the herd. The protocols that are most commonly used in Brazil are based on progesterone (P4) releasing devices that prevent premature estrus and ovulation; and estradiol (E2) to synchronize the initiation of a new follicular wave. In such protocols, administration of equine chorionic gonadotropin (eCG) helps the development of the follicle, increases ovulation rate, improves the endocrine and uterine environment during proestrus and diestrus, and improves fertility. The use of eCG in TAI protocols for suckled cows, non-lactating cows and heifers increases the pregnancy rate allowing more calves at the end of the breeding season and higher profitability to the cattlemen

Avaliação da influência da esterilização por radiação gama nas propriedades mecânicas, estruturais e na biocompatibilidade de matrizes híbridas orgânico-inorgânicas

Atualmente, as pesquisas acadêmicas e industriais não estão voltadas apenas para a descoberta de novos fármacos, mas também para novas maneiras de administração de medicamentos pretendendo obter melhores ações farmacológicas alem de reduzir efeitos colaterais. Partindo deste pressuposto, estudos demonstram que inúmeras moléculas podem ser incorporadas a polímeros híbridos orgânico-inorgânico preparados pelo processo sol-gel, assim pretende-se estudar a possibilidade de sua aplicação no desenvolvimento de um dispositivo de liberação controlada de fármacos na forma de implantes subcutâneos. As matrizes hibridas para serem implantadas devem, necessariamente, ser estéreis. Para isto este trabalho analisa a interação entre o processo de esterilização e uma provável alteração estrutural nestes polímeros. A esterilização por calor úmido em autoclave e a esterilização por radiação gama foram escolhidas para analisar a correlação entre alteração estrutural do hibrido e o processo de eliminação de microorganismos. Outro aspecto que levamos em consideração foi a melhora das características mecânicas das matrizes poliméricas confeccionadas com poli óxido etileno de peso molecular 1900 (POE 1900) e poli óxido propileno de peso molecular 400 (POP 400). Para serem implantadas estas matrizes devem estar uniformes, e não podem trincar ou quebrar antes ou após a implantação. Considerando estes fatores foi adicionado as amostras um agente plastificante, o álcool polivinílico (PVA), na tentativa de melhorar estas características

Acupuntura veterinária em pequenos animais

Acupuncture is one of the oldest forms of treatment, which is based in the grounds of Traditional Chinese Medicine. Despite the ancient history, it’s not completely widespread in Brazil, neither so comprehensive in veterinary medicine as used in humans. The technique of inserting needles into acupuncture points, can also be stimulated by heat, electrical stimulation or implants of metal, is mainly focused on neuromuscular disorders in small animals. The difficulty of comprehension of language and the lack of cientific bases restricted the possible applications of acupuncture. This work will address some of the clinical situations this complementary treatment can act, such as neurological, cardiorespiratory, reproductive, gastrointestinal, immunological, and postoperative intensive care

Estudo sobre o uso do pentacloreto de nióbio, como ácido de Lewis, na síntese de enaminas através da reação de adição de Michael

The NbCl5 being a strong electrophile, is a potential candidate to act as a Lewis acid, and therefore it mediates various organic reactions. For this reason, it has received continuous attention by Brazilian researchers, especially in recent decades, since Brazil holds the largest reserves of niobium, besides being the largest producer of this element. The Michael addition reaction is one of the most widely used for forming carbon-carbon bonds and takes place by the addition of nucleophiles to activated olefins. Although this type of reaction is usually catalyzed by base, there are reports in the literature on the use of various Lewis acids in this type of reaction. The synthesis of enamines based acetilenodicarboxilates and amines, aromatic or alkyl, by Michael addition reaction is quite interesting, since these are valuable synthetic intermediates for the synthesis of heterocyclic and they are used in multicomponent reactions. The derivatives of anilino-fumarate also have a great potential for medical application. In this study we investigated the use of niobium pentachloride as Lewis acid to catalyze the Michael additions between the derivatives of aniline and acetilenodicarboxilates the synthesis of enamines

Sindicalismo cidadão e economia solidária: uma análise da experiência política da Central Única dos Trabalhadores (CUT)

Pós-graduação em Ciências Sociais - FFC

Desenvolvimento de um equipamento para análise de desgastes em prótese de articulação total de quadril

Pós-graduação em Engenharia Mecânica - FEG

Crescimento de apatita na superfície da liga Ti-25Ta empregando dois tipos de tratamento de superfície: biomimético e deposição de polímero por eletrofiação

Titanium and its alloys has been widely used as materials for metallic biomaterials implants are usually employed to restore the hard tissue function, being used for artificial joints and bones, synthetic plates, crowns, dental implants and screws . Objective of this work was the surface modification of Ti-alloy 25Ta from biomimetic surface treatment of employment and deposition of polymer by electrospinning. The league was obtained from the fusion of the pure elements in the arc furnace with controlled atmosphere. The ingots were subjected to heat treatment, cold forged and sectioned discs with 13 mm diameter and 3 mm thick. Two surface treatments was evaluated, biomimetic and electrospinning with PCL fiber. The biomimetic treatment was performed involving alkaline treatment for three molarities 1.5M, 3M and 5M with immersion in SBF. The electrospinning was performed using PCL polymer alloy surface after the alkali treatment Ti25Ta 1M. For this group the polymer coated surfaces were immersed in calcium phosphate containing solution for immobilization of apatite. The results were compared with previous studies using surface treatment group to verify hydroxyapatite formation on the sample surface and it is concluded that the best condition is biomimetic treatment with 5M alkali treatment and heat treatment at 80 ° C for 72 hours

Efeito do recobrimento de filmes de carbono tipo diamante depositados a plasma na manutenção do torque de parafusos protéticos

Pós-graduação em Odontologia Restauradora - ICT

Uso do beta fosfato tricálcio em levantamento da membrana de seio maxilar: estudo histológico, histomorfométrico e imunoistoquímico em coelhos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Processo de reparo ósseo diante de três tipos de superfície de titânio: análise histomorfométrica e por microscopia eletrônica de varredura associada ao EDS: estudo experimental

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O ensino da implantodontia no curso de graduação de odontologia: o relato de experiência de uma instituição e o perfil dos pacientes atendidos na clínica de implantodontia das Faculdades Adamantinenses Integradas - FAI

Pós-graduação em Odontologia Preventiva e Social - FOA

Avaliação da adesão de Staphylococcus spp. em resina acrílica específica para prótese ocular e alteração de cor de botões de íris artificiais, variando a cor e as técnicas de obtenção, ambos após desinfecção química

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Cimentação de coroas com fosfato de zinco sobre munhões de liga de titânio, irradiados ou não por laser

By means of tensile strength, NiCr total crowns were removed from machine-made conical abutments composed by an Ti-6Al-4V alloy. In a total of 20 abutments, 10 were used with it surface presenting high smoothness and 10 abutments had its surfaces modifi ed by laser both cemented with zinc phosphate. The mechanical test was performed at a MTS 810 universal machine adjusted to a speed of 0.5 mm/m. The statistical analysis was done by Levene’s test, which showed homogeneity of variances among groups (F =2.21; p < 0.1). “Student t test” showed that signifi cant differences were found between groups. The modifi cation of the abutment surface through laser caused an increase in pull-out resistance of crowns cemented with zinc phosphate from 430.66 N to 1.514,87 N.