Paepalanthus spp: antimycobacterial activity of extracts, methoxylated flavonoids and naphthopyranone fractions

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Biometria ocular ultrassonográfica e dopplerfluxometria das artérias oftálmica interna e central da retina em macaco-prego (Sapajus spp)

Pós-graduação em Biotecnologia Animal - FMVZ

Caracterização e identificação de moléculas de superfície presentes em Paracoccidioides spp

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Caracterização molecular de cryptosporidium spp. em filhotes caninos

Parasitos do gênero Cryptosporidium pertencem ao filo Apicomplexa, com localização intracelular e extracitoplasmática obrigatória e se desenvolvem principalmente na superfície das células epiteliais de hospedeiros vertebrados. O cão, possível fonte de infecção humana, elimina oocistos fecais deste protozoário com grande potencial zoonótico no ambiente. O presente estudo teve como objetivo caracterizar molecularmente Cryptosporidium spp. obtidos de amostras fecais de filhotes caninos (naturalmente infectados). Um total de 200 cães foram examinados, sendo 100 machos e 100 fêmeas, 111 de padrão racial determinado e 89 sem raça definida (SRD). Destes, 81 animais, 43, 48 e 28 tinham até dois, de dois a três; de três a seis e de seis a doze meses, respectivamente. Conforme sua origem, os animais eram provenientes dos Municípios de Araçatuba e Votuporanga, SP, sendo que 126 eram de domicílios; 11 mantidos em Centros de Zoonoses; 50 de Pet Shops; 12 de um criatório e uma (0,5%) era errante e havia sido adotada. A ocorrência de Cryptosporidium spp. foi de 1% (2/200). Ambas eram fêmeas, SRD, com idade entre 60 e 90 dias. A de origem residencial apresentava fezes pastosas com coloração castanho claro e a outra, resgatada do CCZ, material fecal escurecido de consistência liquefeita. O sequenciamento dos fragmentos amplificados confirmou a presença de Cryptosporidium canis. A partir dos resultados obtidos neste trabalho, é possível concluir que 2% dos caninos analisados eram hospedeiros de C. canis

Plantas medicinais do SUS: espécies comuns da região de Bauru-SP

This work deals with present and discuss mainly the chemical composition and pharmacological activities of each species of the National List of Medicinal plants of interest to SUS (RENISUS) contained in scientific articles that are found in the Bauru-SP region. Such information compiled in this study may help in the advancement of scientific research, promoting the speed in bibliographic queries these species. In the present work was carried out consultation papers and described in the form of literature review, published information of the species listed in Renisus specific to the Bauru-SP region are: Aloe spp* (A. vera or A. barbadensis), Schinus terebinthifolius = mastic Schinus, trimera Baccharis, Mikania spp* (M. glomerata and M. laevigata), Vernonia condensata, Tabebuia avellanedeae, Chenopodium ambrosioides, Momordica charantia, Phyllanthus spp* (P. amarus, P. niruri, P. tenellus and P. urinaria), Stryphnodendron adstringens = Stryphnodendron barbatimam, pulegium Mentha, Mentha spp* (M. crispa, M. piperita or M. villosa), Plectranthus barbatus = Coleus barbatus, Persea spp* (gratissima or P. americana P.), Bauhinia spp* (B. affinis, B. forficata or B. variegata), Copaifera spp*, Morus sp*, Eugenia uniflora or brasiliana Myrtus*, Psidium guajava, Syzygium spp* (S. jambolanum or S. cumini), Passiflora spp* (P. alata, P. edulis or P. incarnata), Punica granatum and Casearia sylvestris. Studies have shown that the use of plants as alternatives treatment and sustainable use of Brazilian biodiversity has a breakthrough in research regarding the chemical composition of each species of RENISUS relationship. Many phytochemical studies are reported compiled with possible pharmacological indications of each species. Thus enabling the use and production of herbal medicines in SUS

Identification of Candida Spp. In Patients with Denture Stomatitis: Relationship with Gender, Age, Time of Denture use and Newton’s Classification

Epidemiological researches are important to understand the distribution and etiology of oral diseases. The actual researches that show the relationship between patient ages, denture status and denture stomatitis are scarce. So, the aim of this study was to identify of Candida spp. in patients with Denture Stomatitis (DS) and to correlate with gender, age, time of denture use and Newton’s classification. 204 complete denture patients (46 males and 158 females) were selected. DS was classified according to Newton’s classification and it was related to gender, age and time of denture use. Samples from the palatal mucosa and the surface of the upper denture of patients with DS were evaluated using PCR test for identification of Candida species. T-test, chisquare and Fisher’s exact tests were used for statistical analysis. DS was evidenced in 54.4% of the sample. According to gender 41.3% of the males and 58.3% females had the disease and the differences were statistically significant (p = 0.032). The type of DS was directly influenced by the time of denture use (p<0.001), but it was not significantly related to the age of the participants (p>0.05). C. albicans, C. tropicalis, C. glabrata, C. krusei and C. dubliniensis were identified by PCR test. DS is more prevalent in women and the prevalence of DS was influenced by the time of denture use (years). C. albicans was identified as the most frequent specie in patients with DS.

Prevalence of Candida spp. during radiographic examination in Diabetes mellitus patients

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Estrutura genética de populações de Rhizoctonia oryzae-sativae do arroz em São Paulo, Brasil, e em meta, Colômbia, e potencial adaptativo do patógeno à Urochloa spp

Pós-graduação em Agronomia - FEIS

A origem de populações emergentes do patógeno da queima-da-folha (Rhizoctonia solani AG-1 IA) da Urochloa spp. na Amazônia e seu potencial de adaptação a outros agroecossistemas brasileiros

Pós-graduação em Agronomia (Genética e Melhoramento de Plantas) - FCAV

Mast cell concentration and skin wound contraction in rats treated with Brazilian pepper essential oil (Schinus terebinthifolius Raddi)

PURPOSE: To evaluate wound contraction and the concentration of mast cells in skin wounds treated with 5% BPT essential oil-based ointment in rats. METHODS: Twenty rats, male, of adult age, were submitted to skin surgery on the right (RA) and left antimeres (LA) of the thoracic region. They were divided into two groups: control (RA - wounds receiving daily topical application of vaseline and lanolin) and treated (LA - wounds treated daily with the topical ointment). The skin region with wounds were collected at days 4, 7, 14 and 21 after surgery. Those were fixed in 10% formaldehyde and later processed for paraffin embedding. Sections were obtained and stained by H.E for histopathology analysis. The degree of epithelial contraction was measured and mast cell concentration were also evaluated. RESULTS: The treated group showed higher mast cell concentrations (p<0.05) associated with increased contraction at day 7 and 14 respectively. CONCLUSION: Ointment containing 5% Brazilian pepper tree oil increases mast cell concentration and promotes skin wound contraction in rats.

Pesquisa de oocistos de Isospora spp. em passeriformes criados em cativeiro

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Molecular characterisation of Cryptosporidium spp. in lambs in the south central region of the State of São Paulo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Diferença entre as espécies de Timbó (Derris Spp., Fabaceae) de diferentes regiões da Amazônia no controle da Musca domestica L.

The roots' powder of timbo species collected in different regions of Amazonia that were tested in larvae groupings, didn't produce differential significative effects in two strains of Musca domestica. The two species with the greater number of plants used in the trial were Derris urucu and Derris nicou; the individuals from the species came from regions considered as "forestal refugies" during the Amazonian pleistocene. Among each species the plants varied since that inefficient to control, until plants lethals to the fies. This differential capacity for larvae control among plants of the same species, originated from different regions, suggests that both species had their populations isolated, during the quaternary epoch. In regions or "forestal refugies", where both species were represented, D. urucu was superior to D. nicou in the capacity to control larvae. While among plants from F region (Peruvian-East refuge) of the State of Acre, the two species had convergence in the values of damage to larvae groupings. Among the another species, Derris sp. (yellow timbo or watermelon timbo) didn't show differences in larvae control between samples from the two regions; while the species that was introduced in the Amazonia Denis elleptica showed damage in the larvae groupings similar to the most effective plants of D. nicou and D. urucu.

Teores de rotenona em Clones de Timbó (Derris Spp. Fabaceae) de diferentes regiões da Amazônia e os seus efeitos na emergência de Imagos em Musca Domestica L

The rotenone contents analysis in clones of three timbó species permited the classification of these plants based on their efficiency to control Musca domestica larvae. The results showed significant correlations between the rotenone contents in the Derris urucu and D. nicou clones with the capacity to control the larvae. The plants with high rotenone contents were more effective. The rotenone contents, the effect of Derris species clones on the flics and the localization of the plants origin, showed that among the plants could have happened a populational isolation in the Amazonia during the pleistocene epoch. In Derris sp., that presented lower rotenone contents and was ineffective to control of the larvae, these differences were not observed.

Efeito antimicrobiano de múltiplas sessões de tereapia fotodinâmica sobre biofilmes de Candida spp. formados in vitro

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)