482 resultados para Eter (Anestesia)


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A laparoscopia ainda é pouco utilizada como ferramenta para técnicas de reprodução assistida em cervídeos sul-americanos, não havendo informações sobre seus efeitos e protocolos anestésicos seguros para sua realização. Objetivaramse avaliar as possíveis alterações na freqüência cardíaca (FC), respiratória (FR), saturação de oxihemoglobina (SpO2) e temperatura retal (TR) durante a laparoscopia para visualização dos órgãos reprodutivos de seis fêmeas de veado-catingueiro (Mazama gouazoubira) anestesiadas com a associação cetamina (5mg/kg), xilazina (0,3mg/kg), midazolam (0,5mg/kg) e isofluorano. Cada animal, após anestesiado, foi posicionado em decúbito dorsal para realização de duas laparoscopias com insuflação abdominal de CO2 (14,2 ± 2,39mmHg; M ± EPM) com intervalo de 40 dias. Para avaliar os principais eventos da laparoscopia, esta foi dividida em três períodos: animal sem insuflação abdominal (P1), com insuflação abdominal (P2) e insuflação abdominal com os quadris elevados a 45º (P3). O controle foi realizado após 40 dias da última laparoscopia, para isto, cada animal foi novamente anestesiado e mantido em decúbito dorsal por um período de tempo igual ao tempo médio de duração das anestesias realizadas nas laparoscopias, sem que o procedimento laparoscópico fosse realizado. O tempo de anestesia dos controles foi também dividido em P1, P2 e P3, respeitando o tempo médio de duração de cada um destes períodos das laparoscopias. Para análise dos dados foi usado o teste de análise de variância (ANOVA) seguido do teste de Tukey e valores de P<0,05 considerados significativos. Não houve diferença significativa nos parâmetros estudados em nenhum dos períodos estabelecidos para o controle e laparoscopia. Porém, a FR média entre P1 (38,8 ± 4,42) e P3 (32,7 ± 4,81) e a TR média entre P1 (38,2ºC ± 0,17), P2 (37,6ºC ± 0,19) e P3 (37,0ºC ± 0,21) variaram significativamente, independente da laparoscopia. Tais dados permitiram concluir que a laparoscopia não promoveu alterações significativas nos parâmetros avaliados, embora o protocolo anestésico utilizado tenha contribuído para redução da temperatura retal resultando em risco de hipotermia durante a anestesia.

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This study aimed at quantifies the pain in dogs under dissociative anesthesia, across thermal and pressoric stimulus and quantify the reasonable period between two different opioids analgesics. In this study, 30 dogs were used and, divided into three groups of 10 animals each, in which the animals of GI received methotrimeprazine and midazolam put on the same syringe with ketamine. The animals of GII received the same treatment of GI but associated with butorphanol and finally the animals of GIII received the same treatment of GI but associated with buprenorphine. The routine parametric evaluations has been proceeded, although using the thermo algimetry measured in degrees C with the average of 52 degrees C and the pressoric algimetry in Kg. In the thermo algimetry, there has been significant difference in GI at the moments M0, M1, M4 and M5; in GII it was found at M0, M1, M5 and M6 and in GIII it was observed the significant at M0 and M1. It has also been shown in pressoric algimetry significant difference in GI at the moments M0, M2 and M3. Among GII it has observed significant difference at all moments and it has found at M0, M9 in GIII. Thus, it has observed significant differences between all groups; for such the M2 of GII smaller than the others; and M4, M5 of GIII bigger than GI and GII. In the assessment of all periods it was observed significant latent period bigger in GI, however, with reasonable period and short recovery in GII and GIII. In the order hand, the postural tonus recovery it was longer in GIII, followed by GII and finally GI. The used method for the measurement of algic stimulus was efficient, noticing a reasonable analgesic period of 3 hours for butorphanol and 6 hours for buprenorphine.

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The prophylactic effect of ondansetron on subarachnoid morphine-induced pruritus is controversial, while evidence suggests that droperidol prevents pruritus. The aim of this study is to compare the effects of droperidol and ondansetron on subarachnoid morphine-induced pruritus. 180 ASA I or II patients scheduled to undergo cesarean sections under subarachnoid anesthesia combined with morphine 0.2mg were randomized to receive, after the child's birth, metoclopramide 10mg (Group I - control), droperidol 2.5mg (Group II) or ondansetron 8mg (Group III). Postoperatively, the patients were assessed for pruritus (absent, mild, moderate or severe) or other side effects by blinded investigators. Patients were also blinded to their group allocation. The tendency to present more severe forms of pruritus was compared between groups. NNT was also determined. Patients assigned to receive droperidol [Proportional odds ratio: 0.45 (95% confidence interval 0.23-0.88)] reported less pruritus than those who received metoclopramide. Ondansetron effect was similar to metoclopramide [Proportional odds ratio: 0.95 (95% confidence interval 0.49-1.83)]. The NNT for droperidol and ondansetron was 4.0 and 14.7, respectively. Ondansetron does not inhibit subarachnoid morphine-induced pruritus.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Biotecnologia Animal - FMVZ

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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This study aimed at quantifies the pain in dogs under dissociative anesthesia, across thermal and pressoric stimulus and quantify the reasonable period between two different opioids analgesics. In this study, 30 dogs were used and, divided into three groups of 10 animals each, in which the animals of GI received methotrimeprazine and midazolam put on the same syringe with ketamine. The animals of GII received the same treatment of GI but associated with butorphanol and finally the animals of GIII received the same treatment of GI but associated with buprenorphine. The routine parametric evaluations has been proceeded, although using the thermo algimetry measured in degrees C with the average of 52 degrees C and the pressoric algimetry in Kg. In the thermo algimetry, there has been significant difference in GI at the moments M0, M1, M4 and M5; in GII it was found at M0, M1, M5 and M6 and in GIII it was observed the significant at M0 and M1. It has also been shown in pressoric algimetry significant difference in GI at the moments M0, M2 and M3. Among GII it has observed significant difference at all moments and it has found at M0, M9 in GIII. Thus, it has observed significant differences between all groups; for such the M2 of GII smaller than the others; and M4, M5 of GIII bigger than GI and GII. In the assessment of all periods it was observed significant latent period bigger in GI, however, with reasonable period and short recovery in GII and GIII. In the order hand, the postural tonus recovery it was longer in GIII, followed by GII and finally GI. The used method for the measurement of algic stimulus was efficient, noticing a reasonable analgesic period of 3 hours for butorphanol and 6 hours for buprenorphine.

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Um felino macho, sem raça definida, pesando 3,6 kg com 10 anos de idade foi atendido no Hospital Veterinário “Luiz Quintiliano de Oliveira”, apresentando obstrução uretral com indicação para uretrostomia perineal. Ao exame físico geral, observou-se freqüência cardíaca (FC) de 240 bat.min-1, taquipnéia, temperatura retal (TR) de 38,4oC, mucosas normocoradas, tempo de preenchimento capilar de um segundo e desidratação de aproximadamente 5%. Como medicação pré-anestésica, administrou-se cetamina (6mg.kg-1), midazolam (0,15mg.kg-1) e morfina (0,15mg.kg-1) pela via intramuscular. A veia cefálica foi canulada com cateter 24G para administração de Ringer com Lactato de sódio (10mL.kg-1.h-1) e a indução foi realizada por meio da administração de propofol (4,4mg.kg-1) pela via intravenosa. Seguiu-se a intubação orotraqueal com sonda no 4,0 conectando-se a um circuito sem reinalação de Baraka, sendo a manutenção anestésica efetuada com isofluorano em fluxo diluente de oxigênio a 100%. Em seguida, realizou-se a técnica de anestesia peridural com o paciente em posição esternal e membros pélvicos estendidos cranialmente. Após localização do espaço entre as vértebras L7 e S1, introduziu-se uma agulha 13x4,5 percutaneamente até atingir o espaço peridural, administrando-se morfina (0,1mg.kg-1), fentanil (3mcg.kg-1) e lidocaína a 1% com vasoconstritor (1,8mg.kg-1), perfazendo um volume total de 0,25mL.kg-1. Durante o procedimento anestésico, monitorou-se a FC, freqüência respiratória (f), pressão arterial sistólica (PAS), pressão parcial de dióxido de carbono ao final da expiração (ETCO2), temperatura esofágica (TE), saturação periférica da hemoglobina (SpO2) e plano anestésico. O tempo total de anestesia e cirurgia foi de 65 e 50 minutos, respectivamente. O plano anestésico manteve-se estável, sem a necessidade de resgate analgésico. A SpO2, concentração de isofluorano e TE mantiveram-se em 97±2%, 1,3±0,1% e 36,7±0,4oC, respectivamente. Durante a anestesia, observou-se um momento de hipotensão, provavelmente devido ao bloqueio simpático decorrente da anestesia peridural. Tal evento foi tratado com bolus de solução de Ringer com Lactato de sódio (5mL.kg-1) promovendo o retorno da PAS aos valores de normalidade. A recuperação anestésica do animal foi isenta de complicações inerentes ao procedimento anestésico. O emprego de opióides pela via peridural é recomendado em procedimentos cirúrgicos abdominal, torácico, genito-urinário e ortopédico, principalmente em pacientes de alto risco, obesos e idosos. Em humanos, a associação da morfina e fentanil pela via peridural demonstra analgesia pós-operatória superior à promovida pelo uso isolado da morfina. Conclui-se que na espécie felina, a associação de morfina e fentanil pela via peridural pode ser uma boa alternativa para realização de protocolos de anestesia balanceada para uretrostomia.

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The aim of this study was to investigate the use of ropivacaine combined or not with different opioids, for epidural anesthesia in bitches submitted to elective ovariosalpingohisterectomy (OSH). Thirty two mixed-breed female dogs, adults were used with medium weigh of 10.5kg. The animals were premedicated with acepromazine (0.05mg.kg-1, IM) and midazolam (0.2mg.kg-1, IM) and allocated in four experimental groups: group 1(n=8): ropivacaine: 0.3 mL.kg-1; group 2(n=8): ropivacaine + morphine (0.1 mg.kg-1); group 3(n=8): ropivacaine + butorphanol (0.1 mg.kg-1); and group 4(n=8): ropivacaine + tramadol (0.5 mg.kg-1) administered epidurally. Heart and respiratory rate; systolic arterial pressure; rectal temperature; arterial blood gas partial pressures; blood pH; sedation and muscular relaxation degree were evaluated at different experimental moments. The data were submitted to ANOVA and compared by Kruskal Wallis, Friedman, Dunn, Tukey and Chi-square test (p≤0.05). Minimum cardiorespiratory alterations were observed and the group of the ropivacaíne combined with the butorphanol (G3) presented a more cranial blockage, what allowed the accomplishment of OSH without induction in six animals (75%) whereas most of the others needed anesthetic rescue. The results allow us to conclude that the use of ropivacaine sole or combinated with morphine, butorphanol or tramadol, for epidural anesthesia, didn't promote significant cardiorrespiratory depression and the ropivacaine associated to the butorphanol allowed the accomplishment of OSH in bitches.

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Fundamentation: The correction of maxillary transverse deficiencies involves orthodontic and surgical procedures that can be performed before or after skeletal maturity. The surgically assisted rapid maxillary expansion (SAR ME) is performed by osteotomies through the lateral walls of the maxilla, zygomatic and canines buttresses, palatal and pterygomaxillary sutures, causing the maxillary disjunction. Followed by activation of the expander to the desired over-expansion in order to correct intercuspal later. Objective: The purpose of this study was to discuss the issues involved in the diagnosis of maxillary atresia, SAR ME indications, as well as surgical technique, through a case study. Methods: The male patient, 19 years old, had severe transverse maxillary deficiency with facial pattern III , Class III , with great lip incompetence. The patient underwent general anesthesia in a hospital environment, the osteotomies was done according to the technique described by Epker and Wolford (1980). Postoperatively, the patient underwent activations daily for 15 days and after 6 months, the orthodontist installed fixed orthodontic appliance to prepare the patient to orthognathic surgery later. Conclusion: The diagnosis by clinical evaluation and models study is essential for the indication of SAR ME and this procedure provides good predictability in the correction of transverse deficiency, with minimal morbidity.

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A expansão rápida da maxila cirurgicamente assistida (ERMCA) é realizada por meio de osteotomias nos pilares da maxila e na sutura palatina mediana, promovendo a correção da deficiência transversa da maxila. Técnicas menos invasivas foram descritas, visando à realização desses procedimentos sob anestesia local, eliminando os custos de internação hospitalar e trazendo maior conforto aos pacientes. A proposta deste trabalho foi discutir os aspectos envolvidos na simplificação da técnica da ERMCA sob anestesia local por meio do relato de caso clínico-cirúrgico de paciente com 27 anos de idade. Conclui-se que o diagnóstico por meio da avaliação clínica e dos modelos de estudo é essencial para a indicação da ERMCA e esse procedimento proporciona boa previsibilidade na correção da deficiência transversal, com mínima morbidade. Além disso, a utilização de uma técnica minimamente invasiva é efetiva no tratamento de maxilas atrésicas, com índices de recidiva semelhantes aos das técnicas mais invasivas.

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Background: The principles of tissue regeneration to repair alveolar bone defects are based on the fabrication of a biologic barrier with different biomaterials. Therefore, the present study aimed to investigate the guided bone regeneration (GBR) by using membrane of demineralized bovine bone matrix (DBBM) on experimental defects in tibia of dogs. Methods: Four dogs were used and after anesthesia, shaving and antisepsis, two standardized bone defects were created on the right tibia of each animal with trephine drill. In the Control Group, the defects were filled with blood coagulum, while in the Treated Group, a membrane of DBBM was used to cover the defects. After 90 days, animals were sacrificed. Results: In the Treated Group, 67.4% of new bone formation was observed and, in the Control Group, 32.6% of the bone tissue reabsorbed when compared with initial bone volume. The membrane remained intact and no inflammatory tissue was observed on membrane/ bone interface. Conclusion: It was concluded that the use of DBBM is an osteoconductive material, presents biocompatibility and may be promise option to repair bone defects.

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Facial injuries vary in their clinical characteristics and complexity, deserves an appropriate approach for each case, considering that the failures may result in aesthetic and functional changes that can be harmful both functionally and psychologically. Aspects such as exposure time of the injury, anesthesia, suture materials and tetanus prophylaxis are important factors. The objective is to present a case of extensive facial injuries in an automobile accident patient.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)