50 resultados para mecanismo europeo de estabilización
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Pós-graduação em Ciências Biológicas (Farmacologia) - IBB
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Pós-graduação em Microbiologia - IBILCE
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Pós-graduação em Engenharia Mecânica - FEB
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The aim of this study was to verify if α-tocopherol, the main substance of Vitamin E and also the one with the major antioxidant propriety, could offer citoprotection to a stomach damaged by alcohol. There are many forms of α-tocopherol, two forms of them were evaluated; d-l-α-tocopherol, the synthetic form and d-α-tocopherol, the natural form of α-tocopherol. Three experiments were made, all of them having absolute ethanol as the lesion agent, but the period and the doses changed in each of them. In the first two experiments, each group of animals received a different form of α-tocopherol and in the third experiment, they’ve received α-tocopherol p.o. for the period of seven days before the lesion agent was administrated. Moreover, immunohistochemistry assays were made from the stomachs samples of the third experiment to verify possible mechanisms involving nitric oxide and 2-cyclooxygenase. Satisfactory results of citoprotection have been obtained when the two forms were administered in the period of one week at doses of 100 mg/kg for synthetic form and 150 mg/kg for natural type. Nevertheless, the two forms didn’t differ statistically in their effectiveness against ethanol. The immunohistochemistry assays showed an increase of the levels of NO and COX2 in relation with the negative control, although there was no correlation between this increase and the gastroprotective effect. In conclusion, α-tocopherol has gastroprotection effect in some doses, but apparently there is no such a thing like the better the dose, the better the effect; that citoprotection don’t have a relationship with NO neither with COX2; the natural and the synthetic form don’t differ in their gastroprotection effect. More studies must be done looking forward an effective dose and also to understand the mechanisms underlay the citoprotection of α-tocopherol in the stomach
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Nowadays, the automotive industry is working to optimize the design of engines, in order to reduce the fuel consumption with acceptable efficiency ratio. This undergraduate thesis is aimed at perform a kinematic/dynamic analysis of a slider-crank mechanism that is part of a four stroke internal combustion engine, the same engine that was used in the analysis described by Montazersadhd and Fatemi (2007). Two algorithms were developed based on Kane’s method to calculate velocities and accelerations of the mechanism bodies, and provide the acting forces at connecting rod joints. A SimMechanics model was developed to simulate the engine, and monitoring the same parameters that were calculated with the algorithms. The results obtained with both approaches were satisfactory and showed good agreement with the values provided by Montazersadhd and Fatemi (2007). The obtained results showed that the axial component of the rod joint efforts was caused by the pressure exerted on the piston head,whereas the radial component was related with the action of inertia loads. Besides, this thesis presents a connecting rod assembly mesh that is going to be used for static and fatigue finite element analysis in the future
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Pós-graduação em Ciência da Computação - IBILCE
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Pós-graduação em Letras - IBILCE
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In this graduate work we will perform the dimensional reduction of particles of spin s=0, s=1 and s=2 via Kaluza Klein mechanism. The method of Kaluza-Klein dimensional reduction is introduced by the dimensional reduction from D to D
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Pós-graduação em Odontologia Restauradora - ICT