88 resultados para cost benefit analysis


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Modern agriculture demands investments in technology that allows the farmers to improve productivity and quality of their products, aiming to establish themselves in a competitive market. However, the high costs of acquiring and maintaining such technology may be an inhibiting factor to its spread and acceptance, mainly to a large number of small grain Brazilian farmers, who need low cost innovative technological solutions, suitable for their financial reality. Starting from this premise, this paper presents the development of a low cost prototype for monitoring the temperature and humidity of grains stored in silos, and the economic implications of cost/benefit ratio of innovative applications of low cost technology in the process of thermometry of grains. The prototype was made of two electronic units, one for acquisition and another one for data reception, as well as software, which offered the farmers more precise information for the control of aeration. The data communication between the electronic units and the software was reliable and both were developed using low cost electronic components and free software tools. The developed system was considered as potentially viable to small grain Brazilian farmers; it can be used in any type of small silos. It provided reduction of costs of installation and maintenance and also offered an easy expansion system; besides the low cost of development when compared to similar products available in the Brazilian market.

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Background: In the past 10 years, new anticoagulants (NACs) have been studied for venous thromboembolism (VTE) prophylaxis. Objective: To evaluate the risk/benefit profile of NACs versus enoxaparin for VTE prophylaxis in major orthopedic surgery. Methods: A systematic review of double-blind randomized phase III studies was performed. The search strategy was run from 2000 to 2011 in the main medical electronic databases in any language. Independent extraction of articles was performed by 2 authors using predefined data fields, including study quality indicators. Results: Fifteen published clinical trials evaluating fondaparinux, rivaroxaban, dabigatran, and apixaban were included. Primary efficacy (any deep vein thrombosis [DVT], nonfatal pulmonary embolism, or all-cause mortality) favored fondaparinux (relative risk [RR] 0.50; 95% CI, 0.39, 0.63) and rivaroxaban (RR, 0.50; 95% CI, 0.34, 0.73) over enoxaparin, although significant heterogeneity was observed in both series. The primary efficacy of dabigatran at 220 mg, apixaban, and bemiparin were similar, with RRs of 1.02 (95% CI, 0.86, 1.20), 0.63 (95% CI, 0.39, 1.01), and 0.87 (95% CI, 0.65, 1.17), respectively. The primary efficacy of dabigatran at 150 mg (RR, 1.20; 95% CI, 1.03, 1.41), was inferior to enoxaparin. The incidence of proximal DVT favored apixaban (RR, 0.45; 95% CI, 0.27, 0.75) only. Rivaroxaban (RR, 0.45; 95% CI, 0.27, 0,77) and apixaban (RR, 0.38; 95% CI, 0.16, 0.90) produced significantly lower frequencies of symptomatic DVT. The incidence of major VTE favored rivaroxaban (RR, 0.44; 95% CI, 0.25, 0.81), only. Bleeding risk was similar for all NACs, except fondaparinux (RR, 1.27; 95% CI, 1.04, 1.55), which exhibited a significantly higher any-bleeding risk compared with enoxaparin, and apixaban (RR, 0.88; 95% CI, 0.79, 0.99), which was associated with a reduced risk of any bleeding. Alanine amino transferase was significantly lower with 220 mg of dabigatran, (RR, 0.67; 95% CI, 0.79, 0.99) than with enoxaparin. Conclusions: NACs can be considered alternatives to conventional thromboprophylaxis regimens in patients undergoing elective major orthopedic surgery, depending on clinical characteristics and cost-effectiveness. The knowledge of some differences concerning efficacy or safety profile, pointed out in this systematic review, along with the respective limitations, may be useful in clinical practice. © 2013 Elsevier Inc. All rights reserved.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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One of society concerns are preserving the environment and the growing energy demand. These two issues are in conflict since most of the energy used today in some way harms the environment. Then is essential to develop and implement ways to clean and renewable energy. In this way, solar energy stands out as a source of clean energy, renewable, abundant and acessible. Solar energy can be harnessed by photovoltaic cells or by solar collectors. The aim of this article is analysethe yield of the solar heather assembled with hydraulic conductive and plastic bottles using three different materials for hydraulic conductors, in order to compare these efficiences and analyze material which has the best cost-benefit in this type of application. The materials analyzed in this study were copper, aluminum and PVC. For this analysis were assembled three alike solar heaters using each one of these materials, and were done several series of measurements of the temperature water output to each heat with flow between 10 and 30 liters per hour. With these data we can analyze the yield and the performance of copper, aluminum and PVC in this application. So we can conclude that aluminum has a higher efficiency, followed by PVC, and the copper had the lowest efficiency. This behavior kept for all values of flow rates examined

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Habitat loss and fragmentation of landscapes endanger the planet’s biodiversity. Strategies for identify priority areas for conservation and restoration of biodiversity rich areas becomes essential for the planning of the management of these landscape become successful. This study aims to propose a novel, transparent and replicable method for choosing priority areas for restoration, and includes the following steps: (a) identification of regional biodiversity hotspots for conservation; (b) identification of priority areas for restoration with the greatest potential to increase the connectivity of the fragments already existing; (c) estimate the potential richness of understory birds before and after restoration, analyzing the gain of species for the future scenario. In order to identify the corridors to be restored in a future scenario we considered the approach of multiple corridors, which aimed to connect the main fragments within the region through analysis of multi-paths. Already existing regression models were applied to estimate the richness of the landscape considering three models: a) species richness as a function of patch area of the fragment selected as hotspots; b) richness as a function of areas connected by structural corridors and c) connected area for species which are able to access nearby fragments within 20m. The gain of species for future scenario which consider the potential restoration of selected areas was estimated. Based on our results we observed that species that use corridors showed the highest increment of species richness of understory birds. As a result it had to restore corridors to model species with the ability to use forest corridors was the highest gain potential species richness of understory birds. The methods proposed method in this study appears provide new ways to ensures a better cost / benefit relationship for restoration projects by increasing the chances of better reach high levels of...

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Engenharia Elétrica - FEIS

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Introduction and Objective: The synthetic intermaxillary elastic emerged as an alternative for clinical use in patients with latex sensitivity. However, there are disagreements about this elastic protocol use according to the force degradation. The aim of this study was to evaluate, in vitro, the forces generated by latex and synthetic elastics over time. Material and methods: Sample size of 840 elastics were used (420 latex and 420 synthetic), delivering medium strength (Dental Morelli®) with internal diameter of 1/8”, 3/16”, 1/4” and 5/16”. The elastics were randomly divided into 7 groups according to the time of the force measuring and immersed into distilled water at 37°C. To measure the force in each group, the elastics were stretched in six progressive increases of 100% of its internal diameter with the aid of a testing machine Emic and measured up to 72 hours. Data were analyzed with SPSS 16.0, using one-way analysis of variance (ANOVA). Results: Immediate force level of synthetic elastics was statistically higher than latex elastics in all strains, for the same size. However, the latex elastics mean force slightly decreased over time, while the synthetic elastics presented an abrupt decrease. Conclusion: The synthetic elastic presented severe force degradation, jeopardizing the cost-benefit ratio, which indicates a higher replacement frequency. The latex elastic showed better mechanical performance in comparison to synthetic ones.

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The correct distinguishment of microorganisms involved in the periodontal disease pathogen, it is important in the understanding of its progression and adequate treatment planning. Considering this fact, some molecular methods of identification and quantification were developed and are extremely sensitive and precise in the characterization of different bacteria species. The present study aimed to realize a literature review, including studies that realized a comparative analysis between bacterial culture and real time PCR methods in the identification of pathogens. The bacterial culture method can possibly identify new microorganisms and realize antibiotics sensitivity tests. The real time PCR is a microbiologic test that identifies and quantifies bacterial species, through gene amplification of predetermined DNA fragments, with high sensitivity and specificity, and need a shorter operation time of the operator when compared to the bacterial culture method. In this way, to determine a specific diagnostic test, should be considered not only its precision in the identification of microorganisms, but the cost-benefit relationship as well.

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Objetivou-se com este trabalho avaliar o efeito da restrição alimentar nas características de carcaça de cabritos F1 Boer x Saanen. Foram utilizados 21 cabritos, pesando 15 kg de PV, distribuídos em três tratamentos (0, 30 e 60% de restrição). O consumo dos animais do tratamento 0% de restrição determinavam o consumo dos animais dos tratamentos 30 e 60% de restrição. Quando os animais do nível de restrição 0% atingiam 25 kg, estes juntamente com seus pares foram submetidos a jejum de sólido de 24 h e de líquido de 16 h. O abate ocorreu mediante descarga elétrica, seguido de sangria e retirada dos órgãos. Os ganhos de peso foram de 211,03, 126,15 e 11,71g/dia; a eficiência alimentar de 0,20, 0,18 e de 0,03; os pesos de abate de 25,44, 20,91 e 15,82kg para os tratamentos 0, 30 e 60% de restrição, respectivamente. O rendimento de carcaça quente, de carcaça fria e biológico não foram influenciados pela restrição alimentar. Somente a proporção da paleta e a do lombo foram influenciados pela restrição alimentar, com aumento linear do rendimento da paleta e decréscimo linear do rendimento do lombo. Houve efeito da restrição na redução do rendimento de gordura e aumento da proporção de osso. A restrição alimentar em níveis moderados, permitiu a obtenção de carcaças de boa qualidade, com bom rendimento, elevada proporção de músculo e baixa participação de gordura e, dependendo da relação custo:benefício, pode tornar-se boa alternativa para o produtor.

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O manejo de plantas daninhas em ambientes aquáticos requer cuidado diferencial e específico, a fim de evitar a contaminação ou alteração nas funções dos corpos hídricos e otimização do custo-benefício das operações. O estudo das características genéticas de populações de plantas daninhas aquáticas fornece informações que podem auxiliar no seu controle e manejo. A alface-d'água é uma planta aquática flutuante livre amplamente distribuída em todo o Brasil, mas é em ambientes aquáticos eutrofizados que essa e outras espécies de rápido desenvolvimento causam problemas sociais e econômicos, devido à grande massa vegetal produzida. Este estudo caracterizou geneticamente populações de alface-d'água coletadas em 15 reservatórios de hidrelétricas (Barra Bonita-BAB, Bariri-BAR, Ibitinga-IBI, Chavantes-CHA, Salto Grande-SAG, Jurumirim-JUR, Promissão-PRO Jaguari-JAG, Nova Avanhandava-NAV, Mogi-Guaçu-MOG, Limoeiro-LIM, Três Irmãos-TRI, Ilha Solteira-ILS, Jupiá-JUP e Porto Primavera-PPR) do Estado de São Paulo. As análises foram realizadas no NUPAM (Núcleo de Pesquisas Avançadas em Matologia), ligado à FCA/UNESP, campus de Botucatu-SP. A técnica utilizada no estudo da diversidade genética foi o RAPD. Os materiais amostrados nos reservatórios do Estado foram muito similares em sua maioria. As populações de NAV, MOG, IBI, JUR, PRO e CHA foram idênticas geneticamente. BAB e SAG, LIM e TRI também foram muito parecidas, apresentando índice de distância genética de 0,0093 e 0,0178, respectivamente. A grande maioria dos reservatórios estudados (93%) apresentou distâncias inferiores a 0,30, formando um grupo definido. No entanto, a população de Jupiá, em média, foi a que apresentou maior diversidade genética (0,45).

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Objectives: To analyze the healing of autogenous onlay bone grafts in three different situations, focusing on the interface area.Material and methods: Sixteen rabbits underwent autogenous bone graft surgeries in the calvaria. The block bone grafts were positioned in three different situations: direct contact between bone graft and receptor bed, graft interposed by particulate bone, and graft interposed by platelet-rich plasma (PRP). After 7, 15, 30, and 60 days, the specimens were retrieved for histological and morphometric evaluation.Results: All groups healed uneventfully and presented incorporation of the grafts after 30 days. A slightly more evident new bone formation could be observed in the PRP group in the first analyzed period, and an earlier maturation of bone in the last period, although no statistically significant differences were achieved.Conclusion: the use of additional material between the bone graft and the receptor bed when using the onlay technique must be carefully considered, taking into account the size of the reconstruction and the cost/benefit relation. The addition of PRP in between autogenous bone blocks and the receptor bed did not confer significant benefit for the new bone formation and healing on the calvaria of bone of rabbits.