Pacientes em processo diagnóstico de câncer de cabeça e pescoço: aspectos psicológicos, percepções e expectativas

Pós-graduação em Saúde Coletiva - FMB

Avaliação das características histopatológicas e imuno-histoquímicas do fronte de invasão tumoral do carcinoma espinocelular cutâneo de cabeça e pescoço e sua importância no comportamento biológico

Pós-graduação em Patologia - FMB

Segundo tumor em pacientes com neoplasias de cabeça e pescoço

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Trilha do patrimônio histórico, passado que vira presente: publicação de apoio pedagógico que busca estabelecer um elo entre a história e o meio ambiente

Por meio da Secretaria Municipal de Educação, a prefeitura do município de Botucatu implantou, em 2005, um de seus mais importantes projetos de educação complementar, a Escola do Meio Ambiente (EMA). Desde a sua fundação, a EMA tem por objetivo desenvolver e apoiar práticas pedagógicas e pesquisas, que visam à conscientização e responsabilidade socioambiental. Dentre suas diversas atividades, está a Trilha Interpretativa do Patrimônio Histórico, voltada, principalmente, para o 1º e o 9º ano do Ensino Fundamental. O caminho interpretado resgata a cidadania, proporcionando ao aluno recuperar as memórias históricas da cidade, reafirmar a sua identidade e consequentemente, buscar a sua valorização pessoal e social. A história do município começa a sair de um misterioso e velho baú. O momento possibilita abrir espaço para a arte da narrativa. Um cocar fala da cultura indígena, um chapéu de palha, nos leva à época dos tropeiros e um mapa de feltro exemplifica o processo de imigração. Ao término da vivência, os educandos saem à rua, para conhecer, em detalhes, os prédios que ajudaram a construir a nossa história. Através dos métodos de avaliação, utilizados nesses três anos, anotações sobre as observações feitas em trilhas e questionários respondidos pelos professores, pudemos constatar que os alunos sabem muito pouco sobre a cidade e que possuem dificuldade de relacionar fatos históricos com a sua própria existência e com as mudanças que promovem no meio. Observou-se que além de tratar com descaso os prédios históricos, os alunos não conseguem citar dados sobre a fauna e a flora local. O mais preocupante é o fato de que para eles, a cidade não representa o meio ambiente. Logo, ficou clara a necessidade de se produzir um material de apoio que tivesse por objetivo preencher estas... (Resumo completo, clicar acesso eletrônico abaixo)

Jornal do humor: quando a piada vira notícia

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Necrose Asséptica da cabeça do fêmur

Legg-Calvé-Perthes disease is a non-inflammatory aseptic necrosis of the head of the femur that is found in both young animals and humans before the gap in the femur head closes. In the fields of both human and veterinary medicine the cause of this condition is not known for certain. Various factors have been put forward in the literature as being responsible for the incidence of this condition such as: abnormalities in coagulation, changes in blood flow in the arteries, a septic obstruction in the draining of the epiphysis or the upper parts of the femur, trauma, growth cycle, hyperactivity in a child, genetic influences and dietary factors. Case histories in dogs show that the first stages of the condition progress slowly but that limping or putting weight on the limb worsens at 6 to 8 weeks. Some owners talk about a sharp onset in clinical lameness. Other clinical symptoms may include irritability, loss of appetite and knawing at the hair surrounding the affected hip. In the course of physical examination manipulating the hip joint will cause pain to the animal. The advanced stages of the disease may result in restricted amplitude of movement, muscular atrophy and fracturing. In humans the clinical signs are similar, although progression of the disease is slower so that it can be diagnosed at an earlier stage. In veterinary medicine the diagnosis is, in the main, based on case history, clinical symptoms, physical examination and certain related procedures such as radiography. The various diagnoses include physical trauma and dislocation of the medial patella. In human medicine many people have been correctly diagnosed. Whatsmore, there is a range of related procedures that are virtually not available to veterinary medicine such as magnetic nuclear resonance, that show up necroses with great clarity before radiography and cintilography do, and is considered... (Complete abstract click electronic access below)

Retrospecto de lesões radiológicas da cabeça de cães e gatos

Pós-graduação em Cirurgia Veterinária - FCAV

A tecnologia de microarray no estudo do câncer de cabeça e pescoço

(Microarray technology in study of head neck cancer). The microarray technology is a tool for global analysis of gene expression that allows investigating hundreds or thousands of genes in a sample using a hybridization reaction. This technology is based on hybridization between labeled targets derived from biological samples and an array of many DNA probes immobilized on a solid matrix, representing the genes of interest. The simultaneous study of hundreds of genes became the microarray technique a very important tool of global analysis, with applications in several areas, including the study of the development of cancer. Head and neck squamous cell carcinoma (HNSCC) is the fifth most common cancer worldwide, with a global annual incidence of 780,000 new cases. Large-scale studies involving microarrays have identified specific gene expression signatures associated with expression changes in HNSCC samples compared to normal tissue, as well as genes involved in clinical outcome and metastasis. However, the considerable heterogeneity among these studies occurs due to experimental design, number of samples, disease sites and stage, choice of microarray platform and results validation. Thus, there is much to be validated, before the technique has clinical utility. In relation to head and neck neoplasia, the large-scale gene analysis is very important, since the clinical and histopathological methods currently used appear to be insufficient to predict clinical progression and response to treatment. Thus, this approach could result in more effective diagnostic and prognostic and most appropriate therapy for this neoplasia.

Análise de Expressões Idiomáticas Italianas com as lexias 'capo' e 'testa' e seu correspondente 'cabeça', em língua portuguesa. (QUALIS A2)

This study aims to investigate the Idioms (IEs) or combinations related to the Italian lexical units testa and capo, in comparison to the Portuguese lexical unit cabeça. Since they have come from two completely different etyma, they are not perfect synonyms; on the contrary, they gave rise to several expressions that are common to just one lexical units. Corpus selection was made in monolingual Italian general dictionaries and then the data was classified according to each typology: idioms that are common only with the unit capo; idioms just with head; idioms that are synonyms with both; IEs whose translations refer to other parts of the body. As a result, we found that most of the IEs with capo or testa have common semes, but most of them also are specific to one or other lexical unit exclusively, confirming the difference in semantic features between them as well as non-univocity between languages.

Efeito das oncoproteínas virais E6 e E7 do HPV-16 na resposta de células T de pacientes com carcinoma espinocelular de cabeça e pescoço

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Criação de um banco de itens para avaliar o conhecimento do câncer de cabeça e pescoço

Pós-graduação em Odontologia Preventiva e Social - FOA

Tumores de cabeça e pescoço: epidemiologia, fatores de risco, diagnóstico e tratamento

Neoplasias of the head and neck correspond to the fifth most common cancer in the world, with high mortality and morbidity. The aim of this study was to show, through a literature review, a little about the epidemiology, risk factors, diagnosis and therapy of the most common malignant tumors of each anatomical region of the head and neck. The research of the articles was made in MEDLINE data base, with a total of 52 articles used. In this review, we analyze the main aspects related to the tumors of oral cavity, pharynx, larynx and salivary glands. Almost all cancers of the head and neck affecting the mucosa of the upper aerodigestive tract are derived from squamous cells. Therefore, the risk factors between the various types of tumors are similar, with alcohol and tobacco being the main ones. To be composed of several distinct structures, the head and neck tumors deserve a diagnostic and therapeutic approach individualized for each anatomical region. Controllingthe risk factors and doing the right approach, it is expected that the incidence of cancers of the head and neck decreases, thereby reducing mortality from malignant neoplasms worldwide

Doença de Lyme na região de cabeça e pescoço: implicações para a odontologia

Lyme disease (LD) is a systemic inflammatory changes resulting from the direct action of the spirochete Borrelia burgdorferi on the host or indirect damage produced by immune response to this microorganism. This pathogen is transmitted by inoculation in the bloodstream by the tick genus Ixodes and is most commonly found in North America, Europe and Asia. In these regions, the dental community is aware about its commonest clinical symptoms, collaborating with the establishment of a diagnosis. However, in Brazil, the frequent facial or peripheral neurological manifestations, among them the Bell's palsy, ocular disorders, disorders in the temporomandibular joint, as well as paresthesia of upper and lower alveolar nerves are observed. In our country, the diagnosis of Lyme disease is primarily based on clinical symptomatology, but most of cases remain without diagnosis and treatment. Then, the detection of the early manifestations of Lyme disease by health professionals is essential for the proper antibiotic treatment, preventing the progression of the disease, and allowing the establishment of favorable prognostic.

Protocolos de saúde geral e bucal de enfermagem em radioterapia de câncer de cabeça e pescoço: uma revisão comentada

O câncer é um problema de saúde pública mundial, com destaque para a incidência do câncer de cabeça e pescoço, em função da biologia das lesões, custo do tratamento, acompanhamento e ônus social. Seus tratamentos mais utilizados como a cirurgia e radioterapia, apresentam sérios efeitos colaterais de curto e longo prazo, cujo é são complexo. As principais orientações e cuidados no tratamento do câncer de cabeça e pescoço foram obtidos através de revisão de literatura sistemática em bases de dados públicas. O objetivo desta revisão de literatura foi mostrar os principais cuidados na prevenção e tratamento das sequelas da radioterapia desse tipo de câncer. Nesse particular, observa-se a necessidade de um protocolo de enfermagem-odontologia, visto a complexidade e a falta de direcionamento das normas do Sistema Único de Saúde, além da responsabilidade dos cuidados desses pacientes, que ficam a cargo da equipe de saúde, atendendo as suas reais necessidades, tanto pessoais, psicológicas e fisiológicas.