43 resultados para Research Subject Categories::NATURAL SCIENCES::Chemistry::Biochemistry


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The discussions waged by several authors in the field of philosophy of science about scientificity and scientific work often fall to the shock of Sciences, who had long substantiate their studies from the perspective of Natural Sciences. Fact that the man away from research, transforming it into a simple object of study. Among these questions, it is necessary to think in a very scientificity of the humanities, which considers the various types of knowledge that makes up the formation of the individual. In this way, approaching the experience, treated by Agambem Benjamin Larrosa and the educational research with children presents itself as a chance to rethink the current paradigm of Sciences. This gives rise to the objective of this work reflect, based on a research conducted with children and imagetic production, the idea of 'research and its relation to the concept of experience'. We will take as its starting point the elaborations on this concept as presented by Giorgio Agamben. We are assuming that the images of that research, are configured as research papers or research and, in this sense, the research is defined as a documentary research

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Pós-graduação em Educação Escolar - FCLAR

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Natural killer (NK) cell activity was evaluated after the initiation and promotion steps in a medium-term multi-organ bioassay for carcinogenesis. NK cell activity was assessed in vitro by Cr51 release assay at the 4th and 30th weeks of the experiment. Male Wistar rats were sequentially initiated with N-diethylnitrosamine (DEN i.p.), N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN drinking water), N-methyl-N-nitrosourea (MNU i.p.), dihydroxy-di-N-propylnitrosamine (DHPN drinking water) and N,N'-dimethylhydrazine (DMH s.c.) at subcarcinogenic doses for 4 weeks (DMBDD initiation). One group was evaluated at the 4th week and the other was maintained without any further treatment until the 30th week. Two initiated groups were exposed through the diet to 2-acetylaminofluorene (2-AAF) or phenobarbital (PB), from the 6th until the 30th week. Five additional groups were studied to evaluate the effects of each initiator on NK activity. All groups submitted to initiation only, initiation plus promotion, or promotion only, developed significantly more preneoplastic lesions than the untreated control group. The main target organs for tumor development in the initiated animals were the liver and the colon, irrespective of treatment with 2-AAF or PB. NK cell activity was not affected by exposure to genotoxic carcinogens after initiation, at the 4th week. Treatments only with PB or 2-AAF did not change NK cell activity. However, decreased NK cell activity was registered in the group only initiated with DMBDD and in the group given DMBDD+2-AAF. This late depression of NK cell activity at the 30th week could be related to the production of suppressing molecules by the tumor cells.

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Pós-graduação em Saúde Coletiva - FMB

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Pós-graduação em Educação para a Ciência - FC

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This study inserts itself in the research line conceptions on the nature of the science (CNC) in the school atmosphere. More specifically, on that teacher of natural sciences who claims not to be interested in philosophy, it is usually noticed a tendency to understand and to teach a vision of a ready/ finished and unalterable science, which directly influences the students conception of science. Discussed here is the application of a didactic rational reconstruction in high school, the results of which are compatible with a more epistemologically acceptable educational concep tion on the nature of science as something provisory, variable and controversial.

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Pós-graduação em Educação para a Ciência - FC

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The Institutional Program of Initiation to Teaching, the PIBID, has by its nature the training of teachers. Focused on graduate students, the PIBID acts as a proposal for training beyond the mandatory classes, giving to the students that are entering the program, a great opportunity to improve their training as a teacher. Thus, this work focuses on a discussion of the PIBID at the Faculty of Sciences UNESP Bauru, aimed at subprojects of graduate students linked to the areas of Natural Sciences, Mathematics, Physics, Biology and Chemistry, working in an interdisciplinary way. I interviewed five teachers (three area coordinators and two contributors) seeking to verify, in their view, the understanding about the program and what were the major difficulties in the training of teachers. For contributors teachers and coordinators of the subprojects, interdisciplinarity has a very important role in the training of new teachers, and the PIBID allows to work this concept more broadly than just in the mandatory classes. However, a program so big like the PIBID comes with problems and it is in this context that this study was conducted. Coordinator teachers and contributors of the subprojects identified flaws in the program that may affect the activities proposed in the institutional design

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Brazil has a long tradition in the study of medicinal plants. When the Portuguese arrived to the new colony, Pero Vaz de Caminha, the scriber of the fleet, left the first impressions of the local and the inhabitants. He clearly mentions how the Indians use natural dye as tincture to paint their bodies. This article reviews the phytochemical and pharmacological characteristics of these colorants and other medicinal plants recently identified mentioned in this letter.