Vulnerabilidade ao stress e estratégias de enfrentamento de líderes religiosos cristãos

Pós-graduação em Psicologia do Desenvolvimento e Aprendizagem - FC

Análise de impactos ambientais gerados pela implantação de loteamentos fechados de alto padrão

Pós-graduação em Engenharia Civil - FEIS

Educação ambiental e contexto escolar: questões para um programa de pesquisas

In this paper are systematized the discussions conducted by GDP "Research in EA and School Context", in VII EPEA, which have had, as its main axis, themes, authors and theoretical perspectives privileged in research presented at the event and declared themselves affiliated to this GDP. The dialogue with researches from previous meetings and other, aims to deepen the questions posed by the research group. The discussions allowed to identify themes and issues that present themselves as significant and challenging for research in EA in the school context, namely the conversion of schools into sustainable educational spaces; public-private partnerships, with great interest from companies and NGOs in school spaces, waving kits with educational materials produced for the school; lack of investment in public policies for teacher training in EA; tendency to an adherence to critical environmental education, without, however, have clear theoretical and methodological commitments under this option.

Análise do desenvolvimento do turismo no distrito de Gardênia, município de Rancharia/SP

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Os álbuns fotojornalísticos online e a construção do acontecimento: atribuições de sentido a partir da composição imagética dos protestos de junho

Given that the choices involved in the selection of compositional techniques in photography are mediated by values, this article aims to analyze the compositional techniques of photographs published by photojournalistic online albums during the protests of June 2013 in Brazil. These albums feature professional and amateur photographs considered "the best" of this event and, interestingly, the chosen photographs have several composition techniques in common. We will examine these images from the perspective of significant effects that these techniques engender with the objective of examining the meanings that were attributed to that event in those albums.

O comportamento diante do paradigma behaviorista radical

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Copa do mundo de futebol de 1950: critérios de noticiabilidade e análise de conteúdo da cobertura realizada pelo jornalismo de revista brasileiro

Pós-graduação em Comunicação - FAAC

Os (Des) caminhos da sífilis congênita em Botucatu/São Paulo

Pós-graduação em Enfermagem (mestrado profissional) - FMB

Loss of Expression and Function of SOCS3 Is an Early Event in HNSCC: Altered Subcellular Localization as a Possible Mechanism Involved in Proliferation, Migration and Invasion

Background: Suppressor of cytokine signaling 3 (SOCS3) is an inducible endogenous negative regulator of signal transduction and activator of transcription 3 (STAT3). Epigenetic silencing of SOCS3 has been shown in head and neck squamous cell carcinoma (HNSCC), which is associated with increased activation of STAT3. There is scarce information on the functional role of the reduction of SOCS3 expression and no information on altered subcellular localization of SOCS3 in HNSCC.Methodology/Principal Findings: We assessed endogenous SOCS3 expression in different HNSCC cell lines by RT-qPCR and western blot. Immunofluorescence and western blot were used to study the subcellular localization of endogenous SOCS3 induced by IL-6. Overexpression of SOCS3 by CMV-driven plasmids and siRNA-mediated inhibition of endogenous SOCS3 were used to verify the role of SOCS3 on tumor cell proliferation, viability, invasion and migration in vitro. In vivo relevance of SOCS3 expression in HNSCC was studied by quantitative immunohistochemistry of commercially-available tissue microarrays. Endogenous expression of SOCS3 was heterogeneous in four HNSCC cell lines and surprisingly preserved in most of these cell lines. Subcellular localization of endogenous SOCS3 in the HNSCC cell lines was predominantly nuclear as opposed to cytoplasmic in non-neoplasic epithelial cells. Overexpression of SOCS3 produced a relative increase of the protein in the cytoplasmic compartment and significantly inhibited proliferation, migration and invasion, whereas inhibition of endogenous nuclear SOCS3 did not affect these events. Analysis of tissue microarrays indicated that loss of SOCS3 is an early event in HNSCC and was correlated with tumor size and histological grade of dysplasia, but a considerable proportion of cases presented detectable expression of SOCS3.Conclusion: Our data support a role for SOCS3 as a tumor suppressor gene in HNSCC with relevance on proliferation and invasion processes and suggests that abnormal subcellular localization impairs SOCS3 function in HNSCC cells.

The 844ins68 cystathionine beta-synthase and C677T MTHFR gene polymorphism and the vaso-occlusive event risk in sickle cell disease

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Measurement of the underlying event activity at the LHC with √s = 7 TeV and comparison with √s = 0:9 TeV

A measurement of the underlying activity in events with a jet of transverse momentum in the several GeV region is performed in proton-proton collisions at √ s = 0:9 and 7TeV, using data collected by the CMS experiment at the LHC. The production of charged particles with pseudorapidity |η|<2 and transverse momentum pT >0:5 GeV/c is studied in the azimuthal region transverse to that of the leading set of charged particles forming a track-jet. A significant growth of the average multiplicity and scalar-pT sum of the particles in the transverse region is observed with increasing pT of the leading trackjet, followed by a much slower rise above a few GeV/c. For track-jet pT larger than a few GeV/c, the activity in the transverse region is approximately doubled with a centreof- mass energy increase from 0:9 to 7TeV. Predictions of several QCD-inspired models as implemented in pythia are compared to the data.

Measurement of the underlying event activity in pp collisions at √s = 0.9 and 7 TeV with the novel jet-area/median approach

The first measurement of the charged component of the underlying event using the novel jet-area/median approach is presented for proton-proton collisions at centre-of-mass energies of 0.9 and 7 TeV. The data were recorded in 2010 with the CMS experiment at the LHC. A new observable, sensitive to soft particle production, is introduced and investigated inclusively and as a function of the event scale defined by the transverse momentum of the leading jet. Various phenomenological models are compared to data, with and without corrections for detector effects. None of the examined models describe the data satisfactorily. © 2012 SISSA.

Event shapes and azimuthal correlations in Z plus jets events in pp collisions at root s=7 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Study of the underlying event at forward rapidity in pp collisions at root s=0.9, 2.76, and 7 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Jet and underlying event properties as a function of charged-particle multiplicity in proton-proton collisions at root s=7 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)