55 resultados para Bio Oss
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Pós-graduação em Filosofia - FFC
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Pós-graduação em Serviço Social - FCHS
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Bio-molecular computing, 'computations performed by bio-molecules', is already challenging traditional approaches to computation both theoretically and technologically. Often placed within the wider context of ´bio-inspired' or 'natural' or even 'unconventional' computing, the study of natural and artificial molecular computations is adding to our understanding of biology, physical sciences and computer science well beyond the framework of existing design and implementation paradigms. In this introduction, We wish to outline the current scope of the field and assemble some basic arguments that, bio-molecular computation is of central importance to computer science, physical sciences and biology using HOL - Higher Order Logic. HOL is used as the computational tool in our R&D work. DNA was analyzed as a chemical computing engine, in our effort to develop novel formalisms to understand the molecular scale bio-chemical computing behavior using HOL. In our view, our focus is one of the pioneering efforts in this promising domain of nano-bio scale chemical information processing dynamics.
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Studies using bio(muco)adhesive drug delivery systems have recently gained great interest, which can promote drug targeting and more specific contact of the drug delivery system with the various absorptive membranes of the body. This technological platform associated with nanotechnology offers potential for controlling drug delivery; therefore, they are excellent strategies to increase the bioavailability of drugs. The objective of this work was to study nanotechnology-based polymeric bio(muco)adhesive platforms for controlling drug delivery, highlighting their properties, how the bio(muco)adhesion can be measured and their potential applications for different routes of administration.
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Pós-graduação em Reabilitação Oral - FOAR
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Mass spectrometry is an analytical technique widely used in several areas of academic research. It allows the knowledge of the information about the micro-world of atoms leading to significant advances in science today. The analysis of stable isotopes of carbon, hydrogen, oxygen, nitrogen and sulfur, also known as bio-elements, shows itself as a major area of interest in using the proposed method. The development of techniques and equipment coupled with mass spectrometry promises to deliver even greater progress in this field, in particular, for the biological sciences and related areas. The pyrolytic method in reduction of organic compounds at high temperatures provides simultaneous isotopic analysis of bio-elements H and O, by the gases released, H2 and CO after the pyrolitic process, significantly reducing analysis time and the amount of material to sample. This paper presents a review of mass spectrometry with its basic principles of operation, and pyrolytic method for reducing compounds at temperatures above 1400 ° C for isotopic analysis of bio-elements
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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The anticancer drug paclitaxel was encapsulated into a bio-nanocomposite formed by magnetic nanoparticles, chitosan and apatite. The aim of this drug carrier is to provide a new perspective against breast cancer. The dynamics of the pure and encapsulated drug were investigated in order to verify possible molecular changes caused by the encapsulation, as well as to follow which interactions may occur between paclitaxel and the composite. Fourier transformed infrared spectroscopy, thermal analysis, inelastic and quasi-elastic neutron scattering experiments were performed. These very preliminary results suggest the successful encapsulation of the drug.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)