Estudo dos compostos voláteis da decomposição térmica dos anti-helmínticos Albendazol e Mebendazol

The albendazole and mebendazole drugs are benzimidazole derivatives and belong to the anthelmintic class. These drugs are particularly recommended for the treatment against worms present in the gastrointestinal tract of animals and humans, by acting directly on the worm metabolism. The need for thermally study drugs is related to all the parameters that these analyzes include: presence or absence of polymorphs, possible changes in the crystallinity of the drugs, as well as the quality control during the manufacturing process thereof. In this study the thermal behavior of anthelmintic albendazole and commercial mebendazole and its recrystallisation in organic solvents, such as acetic acid and formic acid in dimethylformamide to mebendazole, and albendazole were studied using TG-DSC techniques, TG-FTIR, FTIR and XRD. TG-DSC techniques were used so it could collect information about the thermal stability of the compounds steps for thermal decomposition process and also prove its melting temperature. For recrystallization of drugs in organic solvents, the TG-DSC curves were analyzed to compare and determine that the occurrence of polymorphs. The coupled TG-FTIR technique allowed the analysis of volatile products which were released during the thermal decomposition of the commercial mebendazole. The absorption spectroscopy in the infrared region was performed to mebendazole, and albendazole in order to show the difference in functional groups of both, comparing the spectra with commercial drugs and see if there was recrystallized changes in the absorption band where the drug was recrystallized or when heated. The diffraction technique by powder X-ray method was used for comparison of the crystal structures of commercial drugs and recrystallization in organic solvents to identify changes in crystallinity both, which might suggest the formation of polymorphs

Projeto mecânico de um redutor de engrenagens sem-fim numa esteira transportadora inclinada

This work aims to present the design and development of a speed reducer worm gear that will be implemented on an inclined treadmill that aims to raise the load below the top floor. The project start was made with research on issues related to mechanisms and machine elements, and these theories of fundamental importance in the development of device components, along with the help of SolidWorks software that was used to model the main parts of the project and Microsoft Office Excel 2007 was used to alight formulas to perform calculations of the project. All data for calculations were taken from the conditions of the problem to be solved in the best possible way the proposed problem (lifting load from the belt). Following the entire sequence of design gearbox assembly, beginning in pre-sizing and endless selection of electric motor, which consists of an iterative project, then scaling the worm gear and crown, shafts, splines, calculation and bearing selection

Não preferência para alimentação e antibiose em cultivares de amendoim a Stegasta bosquella (Chambers) (Lepidoptera: Gelechiidae)

This work aimed to evaluate the attractiveness, non-preference for feeding and antibiosis in straight and runner growth habit peanut cultivars to Stegasta bosquella (Chambers). Eight cultivars were evaluated, four of straight growth habit (IAC Tatu, IAC 22, IAC 8112 and IAC 5) and four of runner growth habit (IAC Runner 886, IAC 147, IAC 125 and IAC 503). Free-choice and no-choice feeding tests were performed, using pairs of overlapped leaf discs with 1.0 cm diameter, which were placed in Petri dishes where third instar larvae of S. bosquella were released. The attractiveness to the larvae was assessed in predetermined times, in addition to the dry mass consumed. In the antibiosis assay, the biological parameters were evaluated: period and viability of larvae, pre-pupae, pupae, and total, weight of larvae and pupae, sex ratio and longevity. None of the runner growth habit cultivars exhibited non-preference for feeding-type resistance. Among the straight growth habit cultivars, IAC 5 and IAC 22 were the least attractive and consumed in the free-choice feeding test, and IAC 5 and IAC 8112 were the least attractive in the no-choice test. The runner growth habit cultivars IAC 147 and IAC Runner 886 affected the larval survival of S. bosquella, exhibiting antibiosis-type resistance. For the straight growth habit cultivars, IAC 22 and IAC 8112 affected the larval viability, presenting antibiosis-type resistance. The straight and runner growth habit cultivars did not influence the biological parameters of weight of pupae, sex ratio and longevity of S. bosquella.

Measurement of the pp → ZZ production cross section and constraints on anomalous triple gauge couplings in four-lepton final states at √s = 8 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Search for new resonances decaying via WZ to leptons in proton–proton collisions √s=8TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Search for long-lived neutral particles decaying to quark-antiquark pairs in proton-proton collisions at root s=8 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Study of vector boson scattering and search for new physics in events with two same-sign leptons and two jets

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Differential cross section measurements for the production of a W boson in association with jets in proton-proton collisions at √s=7 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Search for displaced supersymmetry in events with an electron and a muon with large impact parameters

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Long-range two-particle correlations of strange hadrons with charged particles in pPb and PbPb collisions at LHC energies

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Search for monotop signatures in proton-proton collisions at root s=8 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Measurements of jet multiplicity and differential production cross sections of Z plus jets events in proton-proton collisions at root s=7 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Search for resonances and quantum black holes using dijet mass spectra in proton-proton collisions at root s=8 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Search for long-lived particles that decay into final states containing two electrons or two muons in proton-proton collisions at root s=8Tev

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Search for supersymmetry using razor variables in events with b-tagged jets in pp collisions at root s=8 TeV

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)