Associação da geoprópolis à quimioterápicos: ação citotóxica e antiproliferativa sobre células HEp-2 e mecanismos envolvidos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeito da infecção e da terapia de erradicação da Helicobacter pylori na expressão gênica de paciente com gastrite crônica

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Marcadores de ativação imune, inflamação crônica e estresse oxidativo em pessoas que vivem com o HIV/Aids: a busca do melhor prognóstico

Pós-graduação em Doenças Tropicais - FMB

Epidemiologia da colonização e infecção microbiana em Unidade de Terapia Intensiva Neonatal: abordagem clínica e molecular

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Caracterização dos compostos derivados de furoxano como inibidores da atividade de bombas de efluxo em Mycobacterium tuberculosis e estudo da influência do efluxo e da halotolerância nos perfis de resistência do bacilo

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Imagens e histórias em arte terapia: experiências nas interfaces da psicologia, da educação e da arte

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Modulação da atividade das interleucinas 17B e 25 associadas à melatonina como indutores de apoptose em cultivo celular de neoplasias mamárias

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Sitios Assistenciais em Unidade de Terapia Intensiva e Relação do Nursing Activities Score com a Infecção Hospitalar

The Patient Classification System has become essential concerning to the practice in management and care from a nurse. This study analyzed the implementation of Assistance Sites in an intensive care unit for adults as a way of organization and classification of patients, as well as the impact of this process on the quality of care according to the Nursing Activities Score and the relation with the Hospital Infection. This is a quantitative, prospective, descriptive and transversal study. The data collection was realized from July until October 2010. The sample was consisted of 214 patients, mostly male, neurosurgical and with a mid age of 57 years. The NAS was on the average of 71.72%. Regarding the Hospital Infection before and after implantation, there was a reduction in the rates of pneumonia. However, the nursing workload remained the same. Moreover, It was evident the importance of using the Nursing Activities Score and the implementation of new ways for classification of patients to improve the organization of the care.

Perfil dos pacientes internados em uma unidade de terapia intensiva pediátrica de um hospital escola do interior de São Paulo

The purpose of the study was to outline the profile of patients hospitalized at the Pediatric Intensive Care Unit of the Hospital das Clínicas de Botucatu - UNESP. This is a descriptive, cross-sectional and quantitative study. The data were extracted from the “Discharge, Admission and Death Register” of the unit of the patients hospitalized between January and December 2011. There was predominance of male children (54.4%) under one year of age (40,7%) were, with a mean length of stay of 5.46 days. Most of these children came from cities included in the DIR XI/SP in Botucatu (78.2%). The discharge contributed with 91.1% of the total discharges from the unit. Most admissions happened during the fall and winter, with the Immediate Post-Operative (IPO - 32.3%) and respiratory diseases (24.2%) as the most frequent causes. The profile of patients at the PICU makes it possible to elucidate individual aspects, family, social, demographic, seasonal, climatic, and, also, the clinical conditions, and, thus, comprehend the context of hospitalizations, in order to propose improvements on assistance, in an individualized and integral manner, for patients and their families.

Morte e morrer em unidade de terapia intensiva pediátrica: percepção dos profissionais de saúde

The objective of this descriptive research was to investigate the perception of health care professionals who work in Pediatric Intensive Care Units in relation to the process of death and dying. The study was undertaken between June and August 2011, with data collected through structured interviews and subjected to statistical analysis. Of the 25 participants, 72% perceived death as a natural process of life, 60% felt compassion – a feeling that did not interfere in caring for the patient, 52% related that they had not received any preparation about the process of death or dying and 76% showed interest in taking a refresher course on the issue. Greater discussion is necessary about academic training, and the offer of educational activities and space for exchanging experiences, such that the workers may better understand and deal with feelings and limitations regarding death.

Inibidores de tirosina-quinase no tratamento de mastocitomas cutâneos em cães: revisão

The mast cell tumor (MCT) is the second most common type of tumor in dogs. It is characterized by uncontrolled proliferation of mast cells in the skin. Treatment involves surgical resection, chemotherapy and radiotherapy. Recently, new treatment protocols have been developed, such as the use of tyrosine kinase inhibitors. With the increasing knowledge about the genome and the evolution of methods in molecular genetics, drugs with specific molecular targets are surely going to become promising therapeutic modalities in the near future. Besides being involved in the normal cell cycle, some studies suggest that tyrosine kinases have a fundamental role in neoplastic processes. Therefore, some strategies such as the development of antibodies anti-receptors for tyrosine kinases and small-molecule tyrosine kinase receptor inhibitors have been developed in an attempt to inhibit tumor development. The purpose of this review is to describe the use of tyrosine kinase inhibitors in the treatment of mast cell tumors in dogs.

Fisioterapia respiratória, pressão intra-abdominal e função renal de pacientes de terapia intensiva

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Caracterização de célula progenitora hepática no cultivo celular de fígado de feto canino

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Cuidados paliativos para pacientes em estado terminal em Unidades de Terapia Intensiva: revisão sistemática e metanálise

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A ressignificação na terapia cognitiva: uma análise a partir do modelo do Sistema de Esquema de Ações e Operações sobre Símbolos e Signos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)