Família Enterobacteriaceae, Acinetobacter baumannii e Pseudomonados na microbiota bucal de pacientes mantidos em unidades de terapia intensiva

Enteric organisms, pseudomonads and other opportunistic microorganisms in the oral microbiota have been linked to serious infections in patients hospitalized in intensive care units (ICU). The present study evaluated the presence of family Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii in the mouth of patients in ICU, correlating it with oral and systemic conditions. Data on health, socioeconomic status, medication use, drug addiction, medical and family histories of patients held for more than 72 hours in the ICU with a diagnosis of severe infection or that developed this condition after entry in said unit were obtained. Fifty patients provided clinical samples of supragingival and subgingival biofilms, saliva and oral mucous membranes were collected, as well as respiratory secretions from patients with pneumonia, blood and urine for sepsis. The presence of target microorganisms was carried out by polymerase chain reaction (PCR) and by culture using selective media. The Chi-square and Mann-Whitney tests were used for statistical analysis, and the significance level was 5%. The intraoral clinical conditions of the patients were poor. The family Enterobacteriaceae was the most prevalent, affecting 39.5% of the supragingival biofilm samples of patients attended in ICU and 18.6% of patients in the control group, besides the rods were the only group found in extraoral samples.

Enterococcus spp. em espécimes clínicos de pacientes atendidos em unidades de terapia intensiva

The relationship between the occurrence of enterococci in the oral microbiota and serious infections in patients hospitalized in intensive care units (ICU) has been established. This study evaluated the presence of Enterococcus faecalis and other species of this genus in the mouths of patients on ICU, correlating it with oral and systemic conditions. Data on health and socioeconomic, medication use, medical and family history of patients maintained for 72 hours in the ICU, diagnosed with severe infection or who have developed this condition after the entry to the unit were obtained. Fifty patients provided intraoral and extraoral clinical samples for analysis (above and subgingival biofilm, saliva and buccal mucosa, followed by obtaining samples of respiratory secretions for patients with pneumonia, and blood and urine for sepsis). The presence of target microorganisms was performed by polymerase chain reaction (PCR) and culture using selective media. The chi-square and Mann-Whitney tests were used for statistical analysis, and the significance level was 5%. The intraoral clinical conditions of the patients showed poor. E. faecalis was significantly more frequent microorganism, followed by E. faecium. The use of broadspectrum antimicrobial action was associated with the presence of these opportunistic microorganisms. These bacteria were more frequent in patients with periodontitis or gingivitis. The results showed that enterococci associated with serious infectious processes may originate from resident microbiota of patients and its prevalence is not elevated in healthy individuals.

Quimiluminescência como fonte de luz alternativa na terapia fotodinâmica

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Síntese e avaliação farmacológica de pró-fármacos derivados do ácido micofenólico úteis na prevenção e no tratamento da rejeição de transplantes

Pós-graduação em Ciências Farmacêuticas - FCFAR

Microbiota bucal e sua relação com infecções oportunistas em pacientes edêntulos mantidos em unidades de terapia intensiva

Pós-graduação em Odontologia - FOA

Estudo comparativo do uso da terapia fotodinâmica antimicrobiana (aPDT) com uso sistêmico de amoxicilina e metronidazol, no tratamento da periodontite crônica em pacientes fumantes

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Associação de antibióticos e terapia fotodinâmica antimicrobiana para o controle de Acinetobacter baumannii

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Contribuições da psicanálise de Freud e Lacan e do materialismo histórico para a terapia ocupacional: uma clínica do desejo e do carecimento na saúde coletiva

Pós-graduação em Psicologia - FCLAS

Adição de ácido linolênico e L-carnitina na maturação oocitária: efeitos sobre o metabolismo celular, potencial de desenvolvimento e criotolerância de embriões bovinos produzidos in vitro

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeito de parâmetros variáveis de fermentação sobre o crescimento celular e composição química do fermentado de batata-doce

This study aimed to evaluate the use of sweet potato as a substrate for the production of spirits. In order to promote an alternative technologically feasible, an experimental design was performed to minimize the operations of preparation, defining the most adequate conditions for the fermentation process. From sweet potato flour obtained by milling and dehydration process of the roots was carried out an enzymatic process of hydrolysis-saccharification of suspension of sweet potato flour with 18% dry matter. The hydrolyzate was used in the fermentation process which followed the 23 full factorial experimental design with central and axial points, and the independent variables were the concentration of reducing sugars, concentration of viable yeast and fermentation temperature. The dependent variables were viable cells, residual sugar, ethanol, glycerol and methanol. The dependent variables were quantified by liquid chromatography. The data analysis indicate that the best fermentation conditions among the tested conditions were: concentration of yeast 5 x 107-1 x 108 in number of viable cells, total reducing sugars from 12.5 to 13.5% and temperature between 33 -34ºC.

Procedimentos de avaliação em terapia de casais a partir de múltiplos instrumentos

Conjugal problems may damage parents and children relationships favoring the appearance of behavior problems, as well as causing psychological problems. Given the lack of studies which value several interrelated behavioral repertoires, the present paper aims at presenting assessment results employing multiple instruments in regards to the three couples that sought clinical services at a University clinic. Results indicated that participants were presenting communication deficits, problem solving difficulties, and problems in expressing affection confirming literature findings. Problems in other areas were also reported, which influenced the marital relationship. It stands out that the children were presenting indications of behavior problems. The relevance of data collection applying different instruments is discussed, and it is necessary that intervention programs consider individual difficulties, besides setting up singular objectives for each person searching for service.

O uso do treino de habilidades sociais em pessoas com fobia social na terapia comportamental

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O uso do treino de habilidades sociais em pessoas com fobia social na terapia comportamental

The effects of an intervention in social skills were assessed in four university students with ages between 19 and 31, with social phobia diagnosis. The performance in social skills as well as performance-compatible disorder was assessed before, after the intervention, and follow-up in four months later, by the instruments: SCID-I, Mini-SPIN, QACC-VU and IHS in a multiple baseline design among participants. The intervention programmed twelve weekly meetings in which the researcher discussed socially skilled alternatives to the described difficulties; leaded dialogued theoretical explanations about the theme of the meeting and also performed functional assessments and repertory training of the participants. It was observed deficits such as public speaking, starting and maintaining conversation in the participants’ social skills repertory, which are consistent with the criteria for social phobia and the difficulties into the adapting to university. After the intervention, the participants left difficulties in public speaking, performance characteristic compatible with the social phobia diagnosis and they also increased social repertory, although it is still necessary the improvement of other skills, such as expressing positive feeling.

Transtorno de estresse pós-traumático e terapia comportamental: um estudo de caso

O presente artigo descreve o caso de uma paciente vítima de abuso sexual na infância que desenvolveu um quadro de Transtorno de Estresse Pós-Traumático (TEPT). Questões relacionadas a abuso sexual, caracterís-ticas do TEPT e formas de tratamento são discutidas. A intervenção foi conduzida na perspectiva da Análise do Comportamento, tendo como foco as queixas da cliente relacionadas ao transtorno, bem como outras demandas, tais como relacionamento com a mãe e a irmã, dificuldades de estudo (faculdade) e aumento de peso. Procurou-se através da intervenção conscientizar a cliente sobre o transtorno e seu tratamento (Psicoeducação), promovendo autoconhecimento, habilidades sociais, refletindo sentimentos e em paralelo foi trabalhada a dificuldade de estudo e o aumento de peso. Como medidas avaliativas da intervenção (pré/pós-teste) foram utilizados instrumentos para rastreamento de TEPT e comorbidades. Conclui-se que a inter-venção foi efetiva para o desaparecimento dos sintomas característicos de TEPT, bem como para a promoção de repertórios relacionados à queixa da cliente.

Terapia ocupacional educacional: revendo o desenvolvimento infantil por meio da teoria histórico-cultural

Pós-graduação em Educação - FCT