Análise comparativa de genes das caseínas de búfalo

Pós-graduação em Genética e Melhoramento Animal - FCAV

Avaliação da precisão de aquisição de dados nos Sistemas CAD/CAM: desadaptação marginal horizontal

Pós-graduação em Odontologia - FOA

Um estudo sobre a equação de Schrödinger biharmônica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Derivados estruturais do peptídeo Histatina-5: síntese e aplicação no tratamento de candidose bucal

O uso contínuo de antifúngicos tópicos e sistêmicos no tratamento convencional de candidose oral tem resultado no aparecimento de Candida albicans resistente. Por este motivo, novas tecnologias para o desenvolvimento de drogas, como os biofármacos, constituem uma estratégia, além de inovadora devido a seu mecanismo de ação, também promissora no campo da biotecnologia. Verificou-se que esta nova tecnologia possui potencial efeito em diminuir a resistência de microrganismos, especialmente do agente etiológico da candidose bucal. A Candida albicans, agente patológico de origem fúngica, expressa diversos fatores de virulência sendo comumente encontrada na pele, cavidade oral, esôfago, trato gastrointestinal e órgão reprodutor feminino podendo acometer pessoas de idades variadas, imunologicamente comprometidas, ou que utilizam próteses dentárias. Nesse sentido, peptídeos com efeito antifúngico, produzidos por plantas, animais e microrganismos estão sendo utilizados como modelos para o desenvolvimento de novas drogas com aplicações em saúde. A Histatina 5 é um peptídeo encontrado na saliva humana com forte propriedade fungicida in vitro. Este peptídeo é extremamente rico nos aminoácidos histidina e lisina e, em pH fisiológico, possui potencial de inibição da formação do biofilme de Candida albicans, podendo ser aplicado portanto, no tratamento da candidose oral. Nesse contexto, o presente estudo consiste na obtenção de análogos da Histatina-5 com modificações em sua estrutura molecular, com o objetivo de otimizar o seu potencial terapêutico já verificado nos peptídeos da família das Histatinas. A Histatina 5SC possui o aminoácido serina C-terminal substituído pela cisteína, o qual é constituído pelo grupo sulfidrila em sua cadeia lateral, para a formação de dímeros. Os peptídeos foram desenvolvidos sinteticamente pelo método de Síntese Orgânica em Fase Sólida, utilizando-se a estratégia Fmoc e...

Desenvolvimento de um novo sistema dinâmico para avaliação da liberação de fármacos

Pós-graduação em Biociências - FCLAS

Orçamento participativo e instituições participativas: aspectos para a avaliação de experiências e casos

This article is to discuss the evaluative perspectives from which it is possible and convenient evaluate the Participatory Budgets (PBs) and the participatory institutions (PIs) that are being experienced in Brazil since the last two decades of the last century. It is proposed an integrated perspective of evaluation of PBs and PIs, in order to avoid partial and biased conclusions, especially those which are based solely or primarily on quantitative methodologies. This discussion is necessary since, in the past five years, the criticism of these experiments has been increasing. Through critical and creative reflection, in essay form, and based on the recent literature on the topic, it is concluded by the need to adopt, in the empirical evaluation, an integrated approach of evaluation of the PBs and the PIs, such as it is proposed in this article. It is conclude also which is fundamental for the theoretical advancement on the subject dedicate special attention to the desirability or not of adopting the criterion of popular participation in government decisions under representative democracy, since it is refuted by public choice and defended by neo-republicanism.

Educação a distância: um estudo analítico das políticas governamentais com foco no projeto da Universidade Aberta do Brasil

The present study at the doctoral level, is in the initial phase of the Program Graduate School of Education UNESP, SP-Araraquara campus. That makes an analysis of government policies in distance education system through the Open University of Brazil (UAB). We present in this moment, the historical background of the creation and expansion of the system of the Open University of Brazil with emphasis on policies of expansion of higher education and also the degree in pedagogy courses offered by the partner universities of the University System in Brazil Open southeast. Among the main objectives of the study is to compare the Brazilian government policies of expansion of higher education with the management and characteristics of undergraduate courses in pedagogy. Partial results indicate a total 51 universities that offer degree courses in pedagogy at UAB system in Brazil, including 12 institutions in the Southeast.

Laboratório de inovação em cognição, informação, tecnologia e aprendizagem: engenharia no ensino médio

Este artigo descreve um conjunto de atividades educativas desenvolvidas no âmbito do projeto “Lab InCognITA – Laboratório de Inovação em Cognição, Informação, Tecnologia e Aprendizagem”, que objetiva promover o desenvolvimento de um conjunto de atividades e projetos com escolas públicas de nível médio, vinculadas à Diretoria de Ensino de Guaratinguetá, buscando despertar o interesse dos alunos para as áreas tecnológicas e engenharias. Destaca-se a importância dos recursos didáticos, em especial os baseados em experimentação, para promover uma melhoria no interesse dos estudantes pelas ciências exatas. A operacionalização do projeto é descrita por meio da apresentação das atividades previstas para o seu desenvolvimento, e de como estas são realizadas durante eventos denominados “Visita à UNESP”, em que alunos das escolas vêm até o Campus da UNESP – Guaratinguetá. Os resultados parciais obtidos sugerem que as atividades desenvolvidas durante as visitas têm contribuído para despertar o interesse dos estudantes para as áreas de Exatas e Engenharias.

Oralidade, letramento e identidade

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Alternativa de tratamento simplificado e integrado da retenção intraóssea de incisivo central superior, associada a odontoma: relato de caso

Permanent teeth impaction is highly prevalent among brazilian people. Its etiology is related to local and general factors association. Permanent teeth retention compromises dental occlusion and when anterior teeth are involved, it also brings esthetics impairments which lead to psychological disturbance. Early diagnosis and adequate treatment are extremely important to solve not only occlusal problems but also psychological aspects. Orthodontic traction of impacted teeth can be conducted by using fixed or removable appliances. Although it depends on patient compliance the use of removable appliances provides an anchorage based on the teeth and the palate reducing undesirable side effects. This paper describes the case of a fourteen years old female patient whose right maxillary central incisor was adequately tractioned with a removable orthodontic appliance. Removable orthodontic devices were used at first to reposition teeth in maxillary anterior area what provided adequate space to allow the placement of the impacted incisor and after were also used to traction and position this tooth. The procedure described seemed to be effective, non expensive and a viable treatment to be performed even on the scope of public health services, extending orthodontic treatment to a higher number of patients.

Sistema Essix MTM: uma alternativa estética para a movimentação

The increased interest in orthodontics by adults has led companies to develop new treatment alternatives that use less visible and more aesthetic orthodontic appliances. The aesthetic aligners stand out among the treatment options that attend these expectations. This paper presented some relevant aspects of these devices, as well as two cases treated with Essix MTM (Dentsply) system, in which all aesthetic and functional objectives proposed treatment have been achieved. The results of this study support the idea that, when properly indicated, aesthetic aligners are a viable treatment option within the clinical routine of the orthodontist.

Autopercepção e condições de saúde bucal em gestantes

This study ev aluated oral health indic ators by determining the pr evalence of dental c aries, periodontal diseases, prosthetic conditions and need in pr egnant women; identifi ed self-perceived oral health status and evaluated association bet ween variables. A clinical examination was performed in fi fty pregnant women assisted in the Preventive Dentistry Clinic-FOAr-UNESP using traditional oral health indicators: DMFT, C ommunity Periodontal Index ( CPI) and pr osthetic c onditions. A semi-struc tured questionnair e was applied to identify oral health perception and to collect sociodemographic variables. For data analysis, pregnant women were allocated in three groups according to their oral health perception (good, fair, poor) and compared according to clinical variables by the Kruskal-Wallis and Dunn tests. DMFT was high, all of them showed periodontal changes, most do not use and do not r equire any type of prosthesis; 36% considered their oral appearance as good. There was signifi cant diff erence between groups for the DMFT index and prosthetic need. It may be concluded that despite dental caries experience of pregnant women was found to be high, the prosthetic need have been detected in most of them and the presence of calculus was observed in all the volunteers, the majority considered their oral health status satisfactory.

Tratamento cirúrgico de canino incluso em mento: relato de caso

The mandibular and maxillary canines when well positioned in the arch, are important functionally and aesthetically. Although these teeth are frequently malpositioned in the dental arch, their absence of eruption are not common, occuring more frequently with the maxillary canine than the mandibular canine. The canine transmigration is a well-known pre eruptive phenomenon in which the tooth goes thru the facial midline, occurring more frequently in the mandible than in maxila. Females are more susceptible than males and the right side more than the left one. Normally the patients do not show any symptoms, and this condition is observed during radiographic exams to diagnose the late exfoliation of the deciduous canine or for any other purpose. Due to the relationship between impacted canines and pathologic lesions, infection, trauma to the adjacent teeth, pain, ectopic eruption and interference with prosthesis, it´s indicated the surgical extraction of these teeth. The goal of this article is to describe and discuss the surgical treatment of an impacted canine (43) in the chin.

Subjective assessment of adhesives usage by complete denture wearers in a brazilian population

The information about the knowledge and usage of denture adhesives is still limited, particularly in Brazilian populations. Objective: The purpose of this study was to investigate the aspects related to the use or nonuse of denture adhesives by complete denture wearers. Material and method: Questionnaires were applied to 100 bimaxillary complete denture wearers concerning their usage of denture adhesives. The survey was carried out according to three categories: those who had never tried adhesive, those who had tried adhesive at least once but no longer used it, and those who currently used it. Result: Of the 100 participants, 80% had never tried adhesives, 16% had tried at least once but no longer used it and 4% had used on a regular basis. Conclusion: Within the limitations of this study, the results of this subjective assessment suggest that within the participants that had never tried adhesives, 77.5% inform that the adhesive is not needed, and all participants who regularly use it inform its efficiency.

Considerações gerais sobre prótese fixa adesiva

The success rate of resin-bonded fixed partial dentures is directly related to the adhesive system and the tooth preparation design for good retention. These resin-bonded bridges represent a prosthodontic alternative, based on their costeffectiveness, conservative techniques, and ease of laboratory manufacturing. Through a thorough review of the literature, this study aimed to report on cavity designs, types of materials used, and the advantages and disadvantages of the resin-bonded fixed partial denture. One of significant advantages of the resin-bonded fixed partial dentures is the conservation of the tooth structure, whereas its main disadvantage includes aesthetic limitations, given that the alloy may in fact be visible. Preparation design, cement type, and casting alloy type, as well as surface treatment, are among the factors that influence the longevity of resin-bonded fixed partial dentures. Treatments with resin-bonded fixed partial dentures present a bright outlook regarding the conservation of tooth structures, as well as a high level of success.