382 resultados para restrição
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Sabe-se que a desnutrição protéica fetal/neonatal pode predispor à resistência à insulina e à síndrome metabólica após recuperação nutricional. O treinamento físico, por sua vez, melhora a tolerância à glicose e a sensibilidade à insulina, além de exercer efeitos benéficos ao crescimento somático. Por outro lado, faltam informações quanto à habilidade de organismos desnutridos muito jovens para a realização do exercício. Modelos animais podem auxiliar a investigação desta questão, uma vez que o estudo em humanos apresenta limitações. Alimentação de ratos com dietas isocalóricas com baixo teor protéico é um modelo de desnutrição bastante utilizado para simular a desnutrição humana. Assim sendo, o presente estudo foi delineado para avaliar a cinética de lactato sanguíneo durante uma sessão de natação de ratos recém desmamados submetidos à restrição protéica fetal/neonatal. Foram avaliados dois grupos de animais recém-desmamados (21 dias, machos), contendo 8 animais em cada um: Normoprotéico (NP), crias de ratas alimentados com dieta normoprotéica (AIN 93G, 17% caseína) durante a gestação e a lactação e Hipoprotéico (HP):crias de ratas alimentados com dieta normoprotéica (6% caseína) durante a gestação e a lactação. Foram analisados peso ao nascer, concentrações séricas de proteínas totais e albumina dos recém-nascidos assim como ao desmame. Os dados foram analisados pelo teste t de student não pareado, sendo o nível de significância pré-estabelecido em 5%. Quando se avaliou os animais recémnascidos observou-se que a restrição protéica neonatal foi eficaz na instalação do quadro de desnutrição visto menores valores referente ao peso corporal, proteínas... (Resumo completo, clicar acesso eletrônico abaixo)
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In the industrial environment the challenge is use better the productive resources: people and machine. The following work has the main goal improve the efficient losses analysis in the stator bar’s production bottleneck equipment situated in the Electric generator’s factory. The action research involved Theory of Constraints on the restriction system identification and developed the data collection framework by losses typology for indicator measurement. The research showed the data collection standardization importance to obtain reliable data and strategic efficiency indicator to optimize equipments. Besides of this, OEE and TEEP indicator demonstrated efficiency results to analyze the actual efficiency when the machine works and the increase capacity opportunity to treat the hide costs in the organization following the continuous improvement
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Nowadays, in business environment, organizations seek to differentiate through special programs and plans, taking the concepts of sustainability, performance and benefits generated for society. Based in this competitive environment, as companies depend on the use of subcontractors to perform services for your different customers, the work performed by them is directly related to the vision created by the final customer’s vision of the company responsible for the project. Considering that the supplier hired to execute the project does not share the strategic concepts related to the level of services to be offered to the final customers, thus creating the need to develop methods that enable the alignment between the project owner, responsible for preparing the executive project, and the supplier, responsible for the execution of the work. Tangent to this need, it was necessary to create a method of evaluation and categorization for suppliers to hired for the projects. As a result it has been proposed a process of categorization of suppliers, through the restriction of possible companies to be hired for a project designed to promote alignment between strategies and continuous improvement of the solutions offered to the market
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Atlantic Forest and Cerrado are between the biological richest areas in the world, for that are considered top conservation priorities. Those ecosystems are found at Botucatu region, where it´s extremely fragmented by routes, agricultural areas and urban centres. This fragmentation causes restrictions on animals populations, in particular to medium and large mammals, that needs larger areas to live and also are often hunted. Even isolated and suffering anthropic influences the fragments are fundamental for local biodiversity conservation. We realized a mammal survey on two forest fragments of Atlantic forest transition to Cerrado of Rubião Júnior – Botucatu – SP – Brazil: Santo Antônio Church and Parque das Cascatas forests. The Santo Antônio church munt is considered a turistic point and its forest receive many visitants, Parque das Cascatas forest is inside of a residential condominium. Both areas are classify as semidecidual stational forest and are disconected by Domingos Sartori route, that connect Botucatu centre to Rubião Júnior district. Around both fragments can be found residences, plantations and pastures. The utilized method included: recognition of tracks on the forests, interviews with next residents and sand plots mounting. The interviews indicated 29 mammals species, and 19 was validated for animal traces, overruns or visualization. Other 3 species found were not mentioned on interviews. Totally, was found 22 small and medium mammals presence evidences on both forest fragments. Parque das Cascatas forest showed more diversity (19) then Santo Antônio Church forest (11), and species like Eira barbara, Procyon cancrivorus, Mazama americana, Shiggurus villosus, Dasypus novemcinctus, Didelphis albiventris, Lutreolina crassicaudata and Lepus europaeus looked for other areas once that was verifyed overruns of individuals... (Complete abstract click electronic access below)
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A teoria em finanças tem evoluído cada vez mais aproximando a teoria financeira às práticas reais adotadas nas empresas e nos mercados financeiros. A partir de Modigliani e Miller, que contribuíram para o ramo das finanças com a teoria da Irrelevância Financeira, o caminho se abriu para uma série de debates a cerca da importância das variáveis financeiras na determinação do valor da empresa. Foram levantados questionamentos a respeito da perfeição dos mercados e apresentado argumentos como a assimetria de informações, os custos de agência, a restrição financeira e outras implicações à teoria do investimento. Atualmente o que se sabe é que o fator investimento está altamente ligado às finanças e, portanto, relaciona-se com os meios de financiamento presentes no mercado e com a organização interna e financeira das firmas, esse ramo de estudo recebe o nome de Finanças Corporativas. Diante da teoria financeira, o objetivo é analisar a indústria siderúrgica de duas economias atualmente em destaque, Brasil e China através da análise econômico-financeira de quatro empresas de capital aberto do setor: Gerdau, Usiminas, Baosteel e Masteel. Cabe destacar que a indústria siderúrgica é base para outras indústrias, como construção civil, automóveis, máquinas, entre outros e, por isso, é tida como sinalizadora do desenvolvimento econômico de um país, assim também, o Brasil e a China são caracterizados como grandes potenciais emergentes e fontes de atração de investimentos internacionais
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The natural resource intensive industries have moved from center to periphery in Brazil. This shift is related to the environmental impacts generated by this type of industry, as occur biggest benefits to these industries in small towns as tax exemptions and donations of land, and local institutional capacity is lower in pollution control. In the 1970s began, in the state of São Paulo, a process of industrial deconcentration of Metropolitan Region of São Paulo to the inside of state, which generated an intense industrialization of the region of Campinas, Ribeirão Preto, Sorocaba e São José dos Campos. This process of industrial deconcentration had support in state policies restricting new industries in the Metropolitan Region and the creation and financing of infrastructure and improvement of road. This research project aims to verify whether there has been a shift of natural resource intensive industries for the Administrative Region of Ribeirão Preto, as well as aspects of the sustainability of this process
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Plumbism is considered the oldest occupational disease. Among the pathophysiological effects associated with lead (Pb) are cardiovascular disorders. Many diseases that develop later in life are determined during the early stages of life, under the influence of exposure and preferred diet of the mother. Still, one should consider that many environmental contaminants at levels not harmful can determine pathophysiological processes if physical or chemical stressors and/or pathological conditions are present. In this context, the intrauterine malnutrition may represent an additional risk factor in exposure to Pb during pregnancy and lactation. For these reasons, the objective of this study was to evaluate the cardiovascular risk of weaned rats that have suffered perinatal exposure to Pb and intrauterine malnutrition, alone or in combination. After mating, female rats were divided into control (ctrl, ad libitum), food restriction (RA, the same diet 50% of consumption in the control group during pregnancy), exposed to Pb (500 ppm Pb in drinking water during pregnancy and lactation) and association (As, received the last two procedures in combination). Cumulative concentration-effect curves (CECs) to CaCl2 and noradrenaline (NA) were obtained in rings with and without endothelium of the same thoracic aorta from male weaned rats (23-25 days old). Maternal weight, litter weight, weight and number of pups at birth, anogenital distance, arterial blood pressure (ABP) and weight of tissues (kidney, liver, aorta, left ventricle) were evaluated. Changes in vascular reactivity were assessed by the maximum response (MR) and 50% effective concentration (EC50). Data were presented as mean ± SEM. Statistical analysis was performed by multifactorial analysis of variance and Tukey's post test. Body weight of dams did not differ between the experimental groups, except on the...(Complete abstract click electronic access below)
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Pós-graduação em Cirurgia Veterinária - FCAV
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Pós-graduação em Engenharia Mecânica - FEB
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The automobile industry is increasingly interested in reducing vehicle weight for greater speed, lower fuel consumption and emissions, through innovation of materials and processes. One way to do this is to seek the replacement of conventional processes by the use of structural adhesives. Structural adhesives are highly resistant materials, which can replace rivets, bolts and welds allowing the substrate / adhesive assemble is stronger than the substrate itself. One of the major advantages of gluing with respect to welding is its esthetic appearance, since it does not leave marks. For this reason, parts to be soldered require a minimum thickness so that the marks do not appear, since the pieces from gluing have no restriction as to the thickness. By replacing the vibration welding process for gluing process of the instrument panel parts of an automobile, one obtains a reduction of the thickness of the parts and therefore it decreases the weight of the car. This work aims to study the various structural adhesives that already exist on the market to be applied on the instrument panel. The mechanical test performed to measure the maximum adhesive strength was the Lap Shear Test at 23°C (room temperature), -35°C and 85°C. The types of adhesives used were the hot-melt and the bi-component. By the results obtained, it is in favor using the bi-component for application to the union of instrument panel parts
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Pós-graduação em Engenharia Elétrica - FEIS
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Pós-graduação em Engenharia Elétrica - FEIS
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Pós-graduação em Zootecnia - FCAV