424 resultados para Seleção dependente de frequência
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Os efluentes de indústrias, como refinarias e petroquímicas, frequentemente contém elevadas concentrações de substâncias tóxicas, dentre elas, os compostos fenólicos. Estas substâncias, mesmo em pequenas quantidades, afetam as propriedades organolépticas da água, além de que durante o processo de cloração da água potável, podem ser transformadas em clorofenóis e policlorofenóis, pela reação com o cloro, formando substâncias com características carcinogênicas. Neste sentido, o refino do petróleo produz grande variedade de poluentes cujas propriedades modificam-se em função dos processos utilizados. Os fenóis são compostos tóxicos, com características fungicida e desinfetante, sendo tóxico para a maioria dos microrganismos, além de apresentarem ação de carcinogenicidade, mutagenicidade e serem recalcitrantes, acumulam-se nos corpos receptores, gerando danos à saúde e à vida aquática. No entanto, embora o fenol possua ação bactericida, alguns microrganismos adquiriram a habilidade de se adaptar e utilizar este composto como fonte de carbono e energia. O presente trabalho pretendeu selecionar linhagens bacterianas, a partir do efluente de uma refinaria de petróleo, da região de Paulínia – SP, que sejam capazes de utilizar altos teores de fenóis como fonte de carbono e energia para seu crescimento e desenvolvimento, a fim de serem aplicadas nas estações de tratamento de efluentes industriais, com foco nas refinarias de petróleo. Foram isoladas 3 linhagens a partir das amostras enriquecidas do efluente da refinaria e, após os ensaios, constatou-se que 1 linhagem apresentou resistência à concentração de fenol de 1.000 mg.L-1. Os ensaios de biodegradação e crescimento em fenol como única fonte de carbono, demonstraram que estas linhagens são capazes de biodegradar aproximadamente 20% do fenol disponível no meio, no período de 24 horas. A quantificação do fenol residual foi realizada em...
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A frequência de micoses invasivas causadas por fungos oportunistas, incluindo leveduriformes, vem aumentando significativamente nas últimas décadas e atinge principalmente indivíduos imunocomprometidos. A tribo Attini possui cerca de 230 espécies de formigas e todas possuem o hábito de cultivar e se alimentar de fungos. Algumas espécies cultivam o fungo mutualista em nódulos poligonais sólidos com 0,25 a 0,50mm de diâmetro, aproximadamente. No interior desses nódulos, encontram-se células na forma de leveduras, que quando semeadas em meio de cultura se desenvolvem como fungo filamentoso. Este tipo de fungicultura está restrito a algumas espécies do gênero Cyphomyrmex. Neste trabalho, isolamos 30 leveduras dos nódulos de oito ninhos de Cyphomyrmex transversus da região de Ilhéus (BA), e analisamos a susceptibilidade aos seguintes antifúngicos: Anfotericina B (AMB), Fluconazol (FCZ), Voriconazol (VCZ) e Itraconazol (ITZ). A caracterização das estirpes foi feita através de métodos morfológicos e moleculares, incluindo-se o sequenciamento dos domínios D1/D2 do rDNA. A avaliação da atividade antifúngica foi realizada através do método de microdiluição, de acordo com a norma M27-A2 (CLSI, 2002). Candida parapsilosis ATCC 22019 e Candida krusei ATCC 6258 foram utilizadas como controle. Os resultados foram interpretados segundo os pontos de corte (breakpoints) aplicados ao gênero Candida. As estirpes foram identificadas como Trichosporon asahii (18), T. coremiiforme (4), Candida carpophila (syn. C. guilliermondii) (4), Galactomyces candidum (syn. Geotrichum candidum) (3) e Cryptococcus laurentii (1). Todas as espécies são conhecidas por possuírem representantes que já foram relatados como patógenos oportunistas. Elas foram sensíveis aos azóis FCZ, VCZ e ITZ, com exceção de G. candidus, cujas estirpes apresentaram sensibilidade dose-dependente a FCZ e ITZ... (Resumo completo, clicar acesso eletrônico abaixo)
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Introdução: A variabilidade da frequência cardíaca (VFC) descreve o comportamento dos intervalos RR que está relacionado às ações do sistema nervoso autônomo (SNA) sobre o nódulo sinusal. Essa pode ser influenciada por diversos fatores dentre eles a obesidade, doença de etiologia multifatorial definida como um acúmulo excessivo de gordura corporal. Objetivo: Avaliar em jovens obesos com idade entre 18 e 23 anos o comportamento autonômico cardíaco, durante o repouso, por meio da análise linear e não linear dos índices da VFC bem como associá-lo a eventos de desconforto músculoesquelético influenciados ou não pela prática regular de exercício físico nessa população. Metodologia: Para a realização deste estudo foram analisados dados de 68 voluntários jovens, de ambos os sexos, distribuídos de forma não randomizada em dois grupos: o G1 constituído por 32 obesos, 20,21 ± 1,66 anos e o G2 por 36 não obesos, 20,8 ± 1,47 anos sendo considerado como critério de classificação dos voluntários o índice de massa corpórea (IMC). O protocolo experimental consistiu da captação da frequência cardíaca batimento a batimento, por meio de uma cinta de captação fixada no tórax do voluntário juntamente com um receptor de frequência cardíaca fixado no punho. Para esta captação o voluntário foi orientado a permanecer em repouso na posição de decúbito dorsal sobre um colchonete, durante 30 minutos, com a respiração espontânea. Além disso, foram aplicados dois questionários, ou seja: versão curta do International Physical Activity Questionaire (IPAQ) - Questionário Internacional de Atividade Física, a fim de classificar o nível de atividade física e o Questionário Nórdico, para detectar eventuais sintomas osteomusculares decorrentes das atividades de vida diária e/ou atividades física. Os índices da VFC analisados foram: análise linear... (Resumo completo, clicar acesso eletrônico abaixo)
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The continuous advance of the Brazilian economy and increased competition in the heavy equipment market, increasingly point to the need for accurate sales forecasting processes, which allow an optimized strategic planning and therefore better overall results. In this manner, we found that the sales forecasting process deserves to be studied and understood, since it has a key role in corporate strategic planning. Accurate forecasting methods enable direction of companies to circumvent the management difficulties and the variations of finished goods inventory, which make companies more competitive. By analyzing the stages of the sales forecasting it was possible to observe that this process is methodical, bureaucratic and demands a lot of training for their managers and professionals. In this paper we applied the modeling method and the selecting process which has been done for Armstrong to select the most appropriate technique for two products of a heavy equipment industry and it has been through this method that the triple exponential smoothing technique has been chosen for both products. The results obtained by prediction with the triple exponential smoothing technique were better than forecasts prepared by the industry experts
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Indivíduos imunocomprometidos possuem maior risco de desenvolver linfomas associados ao EBV. A detecção desse vírus em sangue periférico e a determinação de sua carga viral podem ter importância na evolução clínica de indivíduos portadores do HIV. Foram avaliadas 156 amostras de pacientes HIVpositivos pela reação em cadeia da polimerase em tempo real (qPCR) para detecção e quantificação da carga viral do EBV. 123/156 (78,8%) casos apresentaram carga viral detectável para o EBV, sendo que a carga viral média foi de 6,9x10-3 cópias de EBV/célula. Foi detectada elevada carga viral do EBV em indivíduos com falha terapêutica ou sem HAART (p =0,0076), em coinfectados pelos EBVs 1 e 2 (p=0,0205), em pacientes com altas cargas de HIV (rho=0,27614, p=0,0005) e longos períodos de infecção pelo HIV (rho= 0,24164, p =0,0026) e os que apresentavam altos níveis de linfócitos T CD8 + (rho=0,19286, p =0,0159). A amplificação do gene EBNA-2 para realização da tipagem viral foi possível em 95/123 (77,2%) amostras, das quais 72 (75,8%) revelaram infecção pelo EBV-1, 9 (9,5%) pelo EBV-2 e 14 (14,7%) apresentavam coinfecção entre os EBVs 1 e 2. Esses dados estão de acordo com a literatura visto que o tipo 1 é predominante em países ocidentais e 70,0% da coorte era composta por indivíduos caucasianos e heterossexuais. A maioria dos pacientes que apresentaram coinfecção pelos EBVs 1 e 2 tiveram contagem de linfócitos T CD4 + entre 200 e 499 células/μL de sangue segundo classificação CDC (p =0,0272). Quanto a analise do gene BNLF-1, a amplificação foi possível em 99/123 (80,5%). Desses 50/99 (50,5%) apresentavam a deleção de 30pb no gene, enquanto 49/99 (49,5%) não a possuíam. Em conjunto, os resultados obtidos evidenciam deterioração do sistema imunitário, caracterizada...(Resumo completo, clicar acesso eletrônico abaixo)
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In this work we report the development of a tube amplifier built to be used in magnetic probe diagnostic of plasma. The probe is used to measure the magnetic field in the theta-pinch system presently running in our university. We present the calculations and procedures to determine the configuration of circuits and specify the components of the power supply, the preamp stage and the power stage. The circuit configuration and the characteristics of the components was obtained. A representative model of the system behavior gave the transfer function of the amplifier. Theoretical predictions of frequency response and the feedback effects were compared to the experimental values and showed very good agreement. The amplifier works between a frequency bandwidth of 20 an 30 kHz and supply a maximum power of 12 W
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The Kaposi-associated Herpesvirus (KSHV) also known as Human Herpesvirus 8 (HHV-8) is associated with the development of Kaposi’s sarcoma (KS) and others limphoprolipheratives diseases such as Primary Effusion Lymphoma (PEL) and Multicentric Castleman Disease (MCD). Even though the virus is considered lymphotropic, it is able to infect others cell types such as macrophages, dendritic cells, endothelial cells, monocytes and fibroblasts. After infection, KSHV be latent expressing essential viral genes to its maintenance in a infected cell. However, in some circumstances may occur the reactivation of lytic cycle producing new viral particles. K1 protein of KSHV interferes in the cellular signaling inducing proliferation and supporting cellular transformation. K1 is encoded by viral ORF-K1, which shows high variability between different genotypes of KSHV. So far, it is not clear whether different isoforms of K1 have specific immunobiological features. The KSHV latency is maintained under strict control by the immune system supported by an adequate antigen presentation involving Human Leucocyte Antigen (HLA) class I and II. Polymorphisms of HLA class I and II genes confer an enormous variability in molecules that recognize a large amount of antigens, but also can increase the susceptibility to autoimmune diseases. Therefore, the present study aims to genotype HLA class I (A and B) and class II (DR and DQ) from volunteers to identify haplotypes that can provide better response to K1 epitopes of different KSHV genotypes. First of all, 20 volunteers were selected to genotype HLA genes. In our results we observed prevalence of certain HLA class I haplotypes as HLAA1, HLA-A2, HLA-A24, HLA-A26, HLA-B8, HLA-B18 e HLA-B44. After the in silico analysis using BIMAS and SYFPEITHI databases, we observed high scores for epitopes from the B genotype of KSHV, indicating...(Complete abstract click electronic access below)
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The study and selection of an equipment of air conditioner for any type of environment, should be made without overestimate or undersizing the project. The undersizing does not provide an adequate comfort temperature if the environment is too hot because the air conditioner does not remove all the heat necessary in the environment. But if the project is oversized, energy consumption is higher and there is an unnecessary cost. To prevent these failures is necessary to make a calculation of the thermal load on the environment and choose the equipment that has a higher cooling capacity than the calculated heat load and closer to the calculated heat load. In this graduate work will be chosen an air-conditioned equipment for bus, showing the calculations made for the thermal load for various types of heat gain in this type of vehicle. The thermal load on vehicles is more complicated to calculate than in areas because there are several factors that vary with the movement of the vehicle. It will also explain the compression refrigeration cycle, which is the cooling system used in vehicles because it is weightless, compact and lower cost. From the calculated heat load, it will be chosen an air conditioner that best suits the project and, finally, a brief presentation of the selected equipment will be made
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Organizational change is occurring in the Brazilian agribusiness from sugar cane in recent decades. Aspects of management in this sector are being changed due to the importance of its products, especially ethanol and electricity. It is observed in the literature a lack of quantitative studies in this Brazilian sector, particularly the selection of sugarcane varieties for planting. This study proposes the use of Goal Programming (GP) with Data Envelopment Analysis (DEA) to select efficient varieties of sugarcane for planting in a sugar and ethanol milling company. The study allowed the identification of efficient sugarcane varieties. This way, it helped the company to make more reliable decisions, favoring the increase of productivity
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The study of mathematical modeling assists in evaluation of the capacity of production and measurement of generation time of biogas in landfills, enabling the implantation of projects of energy generation from methane. Thus, the work aims, by simulating scenarios of potential methane generation in the landfill in Rio Claro, the use of field data from methane flow and waste grounded parameters as references for selecting values of k e L0 used to estimate methane generation model in LandGEM. As a result it was found that compared the characteristics adopted in the four scenarios recommended by the USEPA literature with those found in the landfill of Rio Claro (high amount of organic matter in the waste landed and daily practice of leachate recirculation), the scenario that apparently better represent the rate of methane generation is the scenario 01, with k = 0.7 and L0 = 96. Now, the adjustment of parameters in relation to the data field of methane flow, the value of L0 which best fits the methane generation from the landfill in Rio Claro is 150, while for k the line behavior that best represents the reality are values between 0.7 and 0.3. Regarding the parameters of the waste grounded, between the suggested values of k, 0,3 is most consistent with the intermediate level of biological degradation of the residue grounded, while L0 due to the biodegradability of the waste, a new value between 120 and 150 may be more appropriate for the study
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Introduction: The triangular index and the Poincaré plot (or Lorenz plot) are the best known indexes obtained from geometric methods. The triangular index (TINN, RRtri) represent the global variability of the subject and SD1, which reflects the parasympathetic component, SD2, index of global variability and its relationship (SD1/SD2) are obtained from the Poincaré plot. Despite the literature showing changes in the cardiovascular system during and after the resistance exercise (RE), aspects related to autonomic modulation of heart against these conditions have not been explored yet, so it is important to evaluate this behavior. Objectives: Analyze the acute effects of RE on the cardiac autonomic modulation during recovery (REC) through analysis of geometric indices of heart rate variability (HRV), applied with different intensities and muscle groups in healthy and active young. Methods: Were evaluated 24 young, 22.25 ± 2.4 years and 24.47 ± 3.08 kg/m2, underwent an experimental protocol of five stages, in the first stage was conducted a test of one maximum repetition (1RM) in upper limbs (UL) and lower limb (LL), and the following steps were initiated interventions to 40 (E) and 80% (F) of 1RM. Considered for HRV analysis the periods: baseline and immediately after exercise, both in supine... (Complete abstract click electronic access below)
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The implementation of an Export and Processing Zone (ZEPs) brings several benefits to the local, state and federal economy, but often, only socioeconomic factors are considered, apart from several other factors that should be analyzed, such as the environment. In this context of industrialization and the struggle for sustainable development, this work propose to incorporate the environmental variable in the decision process for establishing industrial areas, in particular, the ZPE in the city of Fernandópolis, São Paulo state, Brazil, by examining several physical and environmental factors such as slope intervals, geological features, pedological factors and land use. Developed using a multicriteria analysis, a model has been elaborated, where these factors have received a proportional value according with their importance, supported by a GIS tool (Geographical Information System) and remote sensing products, such as images from CBERS satellite and SRTM radar, showing the suited areas for industrial activities, considering environmental conditions. This model may assist to take better decision about the ZPE implementation area and to reduce the negative environmental impacts that would result of poorly planned locations
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The present study sought to develop a methodology to analyze the water quality based on concepts and methods of climate and climatology respectively. In this way, it was tried to relate techniques and methodologies hydro and limno-meteorological with a rhythmic analysis technique developed within the Brazilian geographical climatology to assess and analyze the blooms of cyanobacteria, the main index of water quality found in reservoirs of “Alto Tietê” Basin and consequently the Metropolitan Region of São Paulo, an area of high environmental complexity due to its high degree of development and high population density. The meteorological data used to develop the study were collected from the meteorological station of the IAG / USP and the limnological data were collected from the Hydrological Monitoring System implemented by SABESP in Billings and Guarapiranga reservoirs as well as data laboratory of the same entity. The results obtained by the rhythmic and integrated analyze showed that the process of blooms of cyanobacteria is dependent not only on one specific factor, but a combination of meteorological factors that may disrupt the stability of reservoir and which can, during the stabilization process, provides the necessary conditions to the development of cyanobacteria. It was also shown by the results that the pace of Atlantic Polar Front Entrance during the winter in São Paulo, is a limiting factor to the growth of cyanobacteria due to their high frequency, keeping the reservoir balance throughout the period. Furthermore, another importance of this study is the possibility of prevention and forecasting periods which are inappropriate for the use of these reservoirs mainly for recreational activities