Avaliação dos efeitos promovidos pela sibutramina, associada ou não à nicotina, nos tecidos reprodutivos de ratas albinas

Sibutramine is a drug recommended clinically for the treatment of obesity, but there are women that use the drug for maintenance of body weight. Many time this use occur associate to habit of tabagism, being the nicotine the main toxic compound in the cigarette. The goal of study was to evaluate the side effects promoted by sibutramine, associated or not to nicotine, in the reproductive tissue of adult female rats. Wistar animals (n =30), were distributed in the groups: a) Control A (0.3 mL of distilled water; oral); b) Sibutramine (15 mg/kg of body weight; oral); c) Control B (0.3 mL of saline solution; intraperitoneal); d) Nicotine (4.0 mg/kg of body weight; intraperitoneal); e) sibutramine + nicotine. The treatments were conducted during 30 consecutive days (single dose, daily). Sibutramine, associated or not to nicotine, affected the folliculogenesis and luteogenesis. There were significant alterations (p<0.05) in the thickness of uterine layers, considerate each treatment. In conclusion, the administration isolated of sibutramine or nicotine promoted deleterious effects in the reproductive tissues of female rats and these effects were potential in the group that received both drugs.

A situação atual do ensino médio brasileiro e as propostas para a próxima década: infraestrutura, gestão e formação do profissional que atua no ensino médio

The aim of this paper is to analyze the current brazilian high school situation that refers specifically to issues of infrastructure, training of professionals working in high school and the question of management of high school, because we believe that such questions also may have fundamental importance for both young people who drop out of high school and for young people who stay there. We will discuss these issues (infrastructure, management and training of professionals working in high school) as a reference, on the one hand, the goals and objectives proposed by the last National Education Plan (PNE - Law No. 10.172/2001), and on the other hand, the objectives and goals proposed for these same issues by the new PNE, to run until 2020, emphasizing that this is still under discussion in Congress, therefore, liable to modifications.

A filosofia como modo de vida em foucault

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Parasitos e comensais intestinais em pacientes neoplásicos submetidos à quimioterapia

The objective of this study was to verify the prevalence of intestinal parasites and/or commensals in the neoplastic patients undergoing chemotherapy. Stool samples were analyzed by the method of Lutz (1919) and Rugai (1954), in triplicate. This work was composed of three groups, the first one (GI) formed by neoplastic patients that are not undergoing chemotherapy, the second (GII) comprised patients who were undergoing chemotherapy, and the third group (GIII) consisting of patients who completed chemotherapy. A total of 30 patients (GI-5, GII-18 and GIII-7) were screened at the Assis Regional Hospital of the Unified Health System of Assis, São Paulo.Additional information on antiparasitic treatment and tumor type were obtained by questionnaire. The positivity was 66.7% (20 cases) for intestinal parasites and/or commensals. The helminths were Ascaris lumbricoides (36.7%), Hookworms (20%) and Hymenolepis diminuta (3.3%). Among the highlights are protozoan Giardia lamblia (46.7%), Entamoeba coli (6.7%), E. histolytica /dispar (3.3%), Endolimax nana (3.3%) and Iodameba butschlii (3.3%). The high frequency of intestinal parasites and/or commensals in the neoplastic patients can be attributed to poor personal hygiene and lack of immunity to reinfection and poor knowledge of the prophylaxis of infection by protozoa and helminths. The results indicate the necessity of adopting a new criterion for neoplastic patients undergoing chemotherapy, primarily performing parasitological diagnosis, treatment and monitoring of cure of intestinal parasitic infections in this risk group.

Carnaval X Entrudo: formas de regrar o carnaval no Rio de Janeiro em fins do Século XIX e Início do Século XX

This article aims to discuss the attempts of the authorities in Rio de Janeiro to regulate Carnival festivities and discipline the revelers. Some of the ways to do this in the late nineteenth and early twentieth centuries, are connected to the prohibition of Shrovetide and of the wearing of some costumes by individual masked men, such as Indian and imp costumes, which are associated with backwardness and barbarism, and, therefore, with a period of history that part of the intelligentsia of Rio de Janeiro wanted to forget. Such manifestations were at odds with political, social and cultural transformations, and with the image of modernity that the city of Rio de Janeiro wanted to consolidate in that period.

Por que ainda é importante pensar como um nômade em nosso tempo

This article argues for the existence of a nomadic way of thinking, in accord with Deleuze and Guattari’s proposals throughout their “nomadology”. I will look forward to develop such an argument through of four points: the epistemological, the political, the historical and the ontological one. These four points, in set, describe what we call nomadic thought. Such reflection is defined in the observation of a dominant process that constitutes subjectivities ruled by a “capitalist axiomatic”, in our time. Such process is understood as a nomadic device involving, as its main by-product, what is called of narcissism of the difference. However, if the dominant way of becoming subjects ruled by capitalist society, in our time, is nomadic, is it still worthwhile thinking as a nomad, as pursued Deleuze and Guattari?

Idéias fora do lugar na aula de História: historiografia e conceitos dos alunos sobre escravidão no Brasil

This article makes a historiography discussion about slavery, indicates the advances in combats for an afro-brasilian history and, in view of cultural re-sense shows a need to consider the student’s prior knowledge and content of teaching History. These knowledges are essential to move beyond the denunciation of the violence of slavery and lead to the classroom buildings of the recent historiography on slavery in Brazil in view of breaking of stereotypes and changing attitudes.

Educação comunitária para a participação na gestão democrática de orgainzação não governamental/Ong

This study examined an example of community education of citizens that aimed to encourage their participation in democratic management of a non-governmental organization (NGO). The research problems were based on the NGO perspective and the ideas of community education and democratic management that guides the education of citizens to participate in the management of this organization. This issue has been studied under the perspective of educators and managers of NGO who performed the work focused on this study. We opted for a qualitative approach with a review of academic literature, questionnaires and individual and group interviews. The results indicated that the perspective of NGO adopted is used in Brazil. These organizations have low politicization and minimize conflicts between social groups. This approach seemed to contradict the prospect of democratic management that encouraged the struggle for rights and engagement in the management of the NGO and public spaces. The contradictions between the approaches of NFO and democratic management probably influenced the adoption of two conceptions of community education. One is dedicated to promoting self-help community to solve their social and economic problems and other inspired by Paulo Freire, which encourages popular mobilization for the questioning of capitalist social organization.

Diagnóstico parasitológico de horticultures no monitoramento da contaminação parasitária em ambientes rurais

The objective of this study was to detect possible carriers of parasites and/or commensals between the horticulturists of Fair of the Producer from Upper Paranaiba, Minas Gerais. A total of 30 horticulturists were instructed to collect three stool samples on alternate days during the months of August and September 2007. Horticulturists were positive 40% for one or more parasite and / or dinner, and found: Giardia lamblia (3.5%), Entamoeba histolytica / E. dispar (7%), Entamoeba coli (13%), Endolimax nana (13%) and Ascaris lumbricoides (3.5%). Stool of gardeners is of importance in monitoring parasite sanitary conditions of vegetables sold in urban environments.

Acúmulo de nutrientes e decomposição do palhiço de cana em função de doses de vinhaça

Understanding the influence of vinasse application on trash decomposition and its effects on soil chemical attributes and sugar cane culture is essential for the good management of the production system. The objective of this study was to assess the time of decomposition and nutrient cycling of the green ratoon cane's trash, and their effects on soil fertility and technological components of crops, in terms of vinasse doses. The study was developed in the northwest region of Sao Paulo State - Brazil, under Eutrophic Ultisol, using the RB855453 variety. The experimental design was randomized blocks with split plot in time. The treatments were composed of four doses of vinasse (0, 50, 100 and 200 m(3) ha(-1)). There was a 20.9% reduction in the amount of crop residue remaining after one year review. The vinasse doses increased the ratoon cane's yield, without interfering in the raw material quality. The green cane system, in which the trash is deposited on the soil and vinasse application, changes the dynamics of the trash decomposition and modifies the soil fertility, contributing positively to the crop yield.

Acúmulo de nutrientes e tempo de decomposição da palhada de espécies forrageiras em função de épocas de semeadura

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Análise econômica do milho em sucessão a diferentes adubos verdes, manejos do solo e doses de nitrogênio

Technologies that increase crop yields are possible when providing profitability to the producer. The objective of this study was to evaluate production costs and profitability of maize in production systems in Cerrado. The study was conducted in Selviria (Mato Grosso do Sul State), Brazil, in the years 2009/10 and 2010/11. The experiment was arranged in randomized blocks with four replications in factorial and mixed with tracks. We established 36 treatments, three green manures (Pennisetum glaucum, Crotalaria juncea and intercropping Pennisetum glaucum + Crotalaria juncea), three soil management practices (no-tillage system, "heavy disking" + "levelling disking" and "chisel plow" + "levelling disking") and four doses of N (0, 60, 90 and 120 kg ha(-1)). For economic analysis were estimated operational cost, the gross revenue obtained by the product of the productivity of the treatments and the value of corn (R$ 0,417 kg or R$ 25,00 sc(-1)) and the ratio revenue / cost of treatment. Whereas higher values (revenue/cost > 1) and lower (revenue/cost ratio < 1) as a parameter in the analysis of profitability, it can be concluded that corn under no-tillage had the highest profitability in succession to Pennisetum glaucum growing profitability with increasing N rates, in succession to Crotalaria juncea and in the absence of nitrogen application on the coverage achieved higher profitability compared to other treatments and in succession to the consortium Pennisetum glaucum + Crotalaria juncea doses of N was between 50 and 55 kg ha(-1) offer greater profitability to the cultivation of corn.

Epidemiological profile of hepatitis C virus infection in patients from west region of Minas Gerais State, Brazil

Hepatitis C virus (HCV) is a serious public health problem and is the leading cause of liver transplantation due to cirrhosis and hepatocellular carcinoma. In Brazil, it is estimated that there are approximately 2 to 3 million HCV chronic carriers. Few data regarding HCV infection are available in West region of Minas Gerais State. Due to the absence of an effective vaccine against this important human pathogen and the high costs of antiviral treatment, it is important to conduct epidemiological studies with the purpose of carry out the planning and implementation of measures to prevent hepatitis C in different populations. Therefore, the aim of this study is to describe the epidemiological aspects of HCV patients from West region of Minas Gerais State, Brazil. Sociodemographic data and risk factors for HCV infection were determined from 74 HCV patients from Uberlandia city (Minas Gerais State). Reactive anti-HCV sera samples were submitted to HCV RNA and genotype detection. Most of individuals were male (63.5%) with mean age of 51 years and presenting low socioeconomic status. HCV genotype was determined among 40 samples and the frequencies were: genotype 2 (45%), 1 (37.5%) and 3 (17.5%). Hepatitis C virus (HCV) infection was common among male and low socioeconomic status individuals.

Preferential consumption of larger fruits of Piper arboreum (Piperaceae) by Carollia perspicillata (Phyllostomidae) in the Brazilian tropical dry forest

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

The effects of environmental enrichment on biochemical and metric parameters of aged rats

The enriched environment (EE) is a promoter of physical activity, by its characteristics such as ample room for movement and exploration, presence of wheels, tunnels and toys. The maintenance of animals in enriched environment can bring a range of benefits, but the majority of the researches investigate cognitive parameters and changes related to the nervous system. The aim of this study was to examine the effects of the maintenance of aged rats in enriched cages on biochemical and metric parameters. Wistar rats were randomly distributed (n=6) into two groups during 6 weeks: control (C) in a conventional cage and enriched environment (EE). The body mass were recorded weekly and the body length at the end of the study. After euthanasia, blood was collected for analysis of glucose, triglycerides and the brain was collected for analysis of mass. The EE group had higher brain mass and lower gain of body weight compared to control group. The control group animals had normal values of blood glucose and triglyceride levels, and the maintenance in an EE did not promote changes in these parameters. Therefore, it can be concluded that the EE group increases brain mass and reduces the gain of body weight without changing the blood glucose and triglycerides in aged animals.