359 resultados para Full factorial design
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Brazil is the largest world producer of yellow passion fruit, a fruit crop which is exigent in nutrients, although little studied in relation to phosphorus fertilizing, fundamental on plant establishment. An experiment was carried out during the period of March/2010 to April/2011 in Remigio County, Paraiba State, Brazil, in order to evaluate the vegetative and productive attributes of yellow passion fruit plants under different sources and doses of phosphorus. Treatments were distributed in randomized blocks in tree replications and twelve plants by plot using the factorial design 2 x 5 referring the sources of superphosphate triple and superphosphate simple at levels P2O5 of 0, 12, 18, 24 and 30 g cave(-1). The following variables were recorded: stem diameter, number of productive branches, number of fruits per plant, fruit mass and fruit yield. The sources and doses of phosphorus affected growth and fruit production of yellow passion plants. The triple superphosphate is the most phosphorus efficient source for growth and fruit production of yellow passion fruit. The triple superphosphate dose which promoted the maximum yield of yellow passion fruit is 42.86 g.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Coordenação de Apoio de Pessoal de Nível Superior (CAPES)
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Pós-graduação em Ciência Florestal - FCA
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O desempenho de tratores agrícolas em condições de campo resulta da interação entre pneu e rodado, influenciado pela velocidade de deslocamento. O objetivo deste trabalho foi avaliar o desempenho de um trator agrícola sob diferentes pressões de inflação dos pneus da semeadora (518, 483, and 414kPa) e em duas marchas que proporcionaram velocidades de 3,0 e 6,0km h-1. O experimento foi realizado no campus de Jaboticabal da Universidade Estadual Paulista (UNESP). O delineamento experimental utilizado foi fatorial inteiramente casualizado (3x2), com quatro repetições. A força de tração foi influenciada pela marcha e pela potência exigida; no entanto, a pressão de inflação do pneu da semeadora não alterou esses parâmetros. Além disso, o consumo de combustível foi influenciado apenas pela marcha do trator. O consumo de energia foi maior com o aumento da velocidade, ocasionada pela mudança de marcha. A velocidade de deslocamento foi maior para a pressão de 518kPa, em razão da menor patinagem da semeadora promovida por essa pressão. A patinagem do trator não foi alterada pelos fatores testados.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Egg yolk color may be controlled both by the concentration and the type of xanthophylls added to diets, with the aim of meeting consumers demand. The objectives of this work were to study how yellow and red xanthophylls present in laying hens` diets influence yolks colors and find the concentrations of these ingredients that meet the regional consumer desire. A factorial design 5 x 3 with 5 concentrations of yellow xanthophylls (lutein + zeaxantin 40%; 1.0, 1.25, 1.5, 1.75 and 2.0 mg/hen/d) and 3 concentrations of red xanthophylls (canthaxantin 10%; 0, 0.35, 0.7 mg/hen/d) was used. After a 30 d period receiving corn basal diets and water ad libitum, 60 White Dekalbe hens were distributed to receive the 15 dietary treatments in 4 replicates. Diets were provided daily at 110 g, during 21 d under 16 h light/8 h dark. Yolks colors were evaluated daily using the CIE L, a, b color space and the Roche color index. After the color stabilization, data were analyzed by ANOVA, regression analysis and Response Surface Methodology (MRS). Global acceptance for the Roche colors was evaluated with a 5 points hedonic scale and data were analyzed by Friedman and Dunn tests. Significance was established at 95% (P < 0.05). Regression analysis showed that the red xanthophylls content was the most important factor that defined L, a and b values for yolk color (P < 0.0001; square function), although its effect was significantly affected by the yellow xanthophylls contents (P = 0.0277; P < 0.0001; P = 0.0002 for L, a, b, respectively), providing evidence for a synergistic effect and not for a saturation effect. MRS showed that the highest redness of yolks was reached with 1.5 mg/hen/d of yellow and 0.5 mg/hen/d of red xanthophylls. So, higher supplementations aiming at increasing yolk color would bring an unnecessary cost to the ration. The most accepted yolk color scored 9, which corresponded to mean color attributes L = 65; a = 16; and b = 64. MRS showed that these values could be reached with combinations of yellow:red xanthophylls like 1.0:0.15 or 1.5:0.1 mg/ hen/d or simply with the yellow xanthophylls at 2.0 mg/hen/d. So, it was concluded that both yellow and red xanthophylls are important to define yolks color; that high amounts of xanthophylls are unnecessary to bring changes to color; and that Brazilian consumer requires yolks color attainable with few amounts of red xanthophylls or only with the yellow ones.
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Chemical and physical degradation of drugs may result in altered therapeutic efficacy and even toxic effects. Therefore, the aim of this work was to study the stability of darunavir and to develop and validate a liquid chromatography (LC) method to determine darunavir in raw material and tablets in the presence of degradation products. The novel method showed to be linear from 6.0 to 21.0 μg/mL, with high precision (CV < 2%) and accuracy (recuperation of 99.64%). It is simple and reliable, free of placebo interferences. The robustness of the method was evaluated by a factorial design using seven different parameters. Forced degradation study was done under alkaline, acidic, and oxidative stress at ambient temperature and by heating. The LC method was able to quantify and separate darunavir and its degradation products. Darunavir showed to be unstable under alkaline, acid, and oxidative conditions. The novelty of this study is understanding the factors that affect darunavir ethanolate stability in tablets, which is the first step to unravel the path to know the degradation products. The novel stability-indicating method can be used to monitor the drug and the main degradation products in low concentrations in which there is linearity.
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Pós-graduação em Agronomia (Produção Vegetal) - FCAV