351 resultados para Spleen


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The aim of this study was to obtain a reactive monoclonal antibody against Candida albicans. Spleen celIs of BALB/c mice previously immunized withCandida were fused in vitro with mielorna cells Sp2-0Ag14. The resultant hybridcells were kept in culture medium at 5% C02.The suspension growing cells were tested by ELISA to check the antibodies titer. The positive colonies were cloned to achieve the monoclonal antibody and further expanded in mice peritoneum. The antibody produced was purified and isotope. The monoclonal antibody was denominated 76C. The 76C was directed against mannoprotein molecules from Candida cell surface, which has not yet been completely investigated to find outlhe specific nature of epitope. The antibody 76C was analyzed by DOT BLOTagainst different Candida species and there were positives results in 87,5% of the tested samples_ The monoclonal antibody 76C will be a useful tool to investigate oligomannoside epitope from mannan and could be applied in sera diagnosis in invasive candidiasis and in studies of glicidic epitope.

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The objective of present study was to evaluate the relative growth of organs and viscera from water buffaloes. Fifteen Mediterranean intact males, averaging, 356.7 kg initial live weight and twenty four months of age, were used. The animals were ramdomly assigned into three groups (categories). One group was ramdomly assigned to immediate slaughter (AR), the rest two groups were full-fed a ration containing 50% concentrate, dry matter basis until reaching the slaughter weights of 450 and 500kg, respectively. At slaughter the empty body weight was determined and the weights of head, feet, leather, lungs, heart, liver, spleen, rumen-reticulum, omasum, abomasum, small intestine, large intestine were recorded. Regression equations of log weight of organs and viscera as a function of log empty-body-weight (EBW), were fitted. All body components studied, with exception of liver and spleen, developed slower than in relation to EBW.

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Lymphomas are malignant neoplasm characterized by proliferation of lymphocytes that originate primarily in lymphoid organ such as lymph nodes, liver, spleen and bone marrow. However the feature of continuous migration of lymphocytes in different organs, this tumor can develop in any organ. Although lymphoma is a very common hematopoietic neoplasm in dogs, cardiac location is rare. The diagnosis of primary cardiac lymphoma may be performed when there is involvement of the heart and/or the pericardium without evidence of involvement in other organs. In veterinary medicine there are few reports on the diagnosis, treatment and prognosis of cardiac lymphoma. Therefore, the purpose of this report is to describe a case of cardiac lymphoma in which the patient responded favorably to chemotherapy employee with disease-free interval of 19 months and highlight the importance of including this neoplasm in the differential diagnosis of diseases that affect the cardiovascular system.

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