Neolignans, styrylpyrones and flavonoids from an Aniba species

The trunk wood and barks from an Aniba species contain four esters of benzoic acid with cinnamyl alcohol, five benzofuran neolignans, licarin-A, burchellin, cis-burchellin, burchellin-rearranged and cis-burchellin-rearranged, one tetrahydrofuran neolignan, aristolignin, three bicyclooctane guianin-type neolignans, (7S, 8S, 1'R, 5'R)-4-hydroxy-3,3'-dimethoxy-4',6'-dioxo-8.1', 7.5'-neolignan-Delta: 1,3,5,2',8' and the new (7S, 8S, 1'R, 4'R, 5'S)-4'-hydroxy-3,4,3'-trimethoxy-6'-oxo-8.1', 7.5'-neolignan-Delta: 1,3,5,2',8' and (7S, 8S, 1'R, 4'R, 5'S)-4,4'-dihydroxy-3,3'-dimethoxy-6'-oxo-8.1', 7.5'-neolignan-Delta: 1,3,5,2',8', one new bicyclooctane canellin-type neolignan (7S, 8S, 1'S, 4'R, 5'R, 6'S)-4',6'-dihydroxy-3,4-dimethoxy-3'-oxo-8.1', 7.5'-neolignan-Delta: 1,3,5,8', two styrylpyrones, 4-methoxy-6-(11,12-dimethoxy-trans-styryl)-2-pyrone and 6-(11,12-methylenedioxy-trans-styryl)-4-methoxy-2-pyrone, two styrylpyrone dimers: 4'-methoxy-8-(11,12-dimethoxyphenyl)-7-[6-(4-methoxy-2-pyronyl)-6-(E)-styryl-1'-oxabicyclo[4,2,0]octa-4'-en-2'-one and the new 11,12-dimethoxyphenyl-7,7'-di-[6-(4-methoxy-2-pyronyl)]-cyclobutane and six flavonoids, 3,5-dihydroxy-7,4'-dimethoxyflavone, 5-hydroxy-3,7,4'-trimethoxyflavone, 3,5,4'-trihydroxy-7-methoxyflavone, 2,3-dihydro-5-hydroxy-7,4'-dimethoxyflavone, 2,3-dihydro-3,5-dihydroxy-7-methoxyflavone, 2,3-dihydro-3,5-dihydroxy-7,4'-dimethoxyflavone and a new flavan, 6,7,3',4',5'-pentamethoxyflavan. (C) 1997 Elsevier B.V. Ltd.

Chemistry and evolution of the Piperaceae

The chemistry of members of the family Piperaceae is of great interest owing to the variety of biological properties displayed. A survey of structural diversity and bioactivity reveals that groups of species specialize in the production of amides, phenylpropanoids, lignans and neolignans, benzoic acids and chromenes, alkaloids, polyketides, and a plethora of compounds of mixed biosynthetic origin. Bioassays against Cladosporium cladosporioides and C. sphaerospermun have resulted in the characterization of various amides, prenylated phenolic compounds, and polyketides as potential classes of antifungal agents. Studies on the developmental process in seedlings of Piper solmsianum have shown that phenylpropanoid are produced instead of the tetrahydrofuran lignans found in adult plants. In suspension cultures of P. cernuum and P crassinervium, phenylethylamines and alkamides predominate, whereas in the adult plants prenylpropanoids and prenylated benzoic acids are the respective major compound classes. Knowledge of the chemistry, bioactivity, and ecology of Piperaceae species provides preliminary clues for an overall interpretation of the possible role and occurrence of major classes of compounds.

Application of a Biomimetic Sensor Based on Iron Phthalocyanine Chloride: 4-Methylbenzylidene-Camphor Detection

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Optical chemical sensors using polythiophene derivatives as active layer for detection of volatile organic compounds

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Lignoids; flavonoids and polyketides of Virola surinamensis

From the seeds of Virola surinamensis, which were collected near Altamira and near Maraba, Para State, Brazil, the following substances were isolated by chromatographic techniques: two dibenzylbutanediol lignans, dihydrocubebin and the new dihydrocubebin monolaurate, two furofuran lignans, sesamin and asarinin, three dibenzylbutyrolactol lignans, cubebin, β-O- methylcubebin and α-O-methylcubebin, one dibenzylbutyrolactone lignan, hinokinin, one aryltetralin neolignan, galbulin, two tetrahydrofuran neolignans, galgravin and the new 4'-hydroxy-3'-methoxy-3,4-methylenedioxy- 8.8',7.O.7'-neolignan, one flavone, tithonine, one isoflavone, irisolidone, and two new polyketides, 3-hydroxy-1-(15-phenylpentadecanoyl)-2,6- cyclohexanedione and 1-(5-phenylpentanoyl)-2,6-cyclohexanedione. Different chemical constitutions of the fruits from the two localities were observed.

Estudo da fotossensibilidade de materiais híbridos de sílica dopados com heteropoliânions de tungstênio

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo das propriedades elétricas e ópticas de nanocompósitos transparentes e condutores

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Estudo e caracterização da eletropolimerização de moléculas nanoestruturadas a Base de Schiff

Pós-graduação em Química - IBILCE

Híbridos orgânicos-inogânicos aminosilano-ácido ricinoleico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo metabolômico e proteômico em Peperomia blanda (Piperaceae)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Sesquiterpenos e lignanas de Holostylis reniformis

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo detalhado da síntese de melanina em DMSO

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Estudo termoanalítico e caracterização no estado sólido dos anti-hipertensivos: atenolol, besilato de anlodipino e maleato de enalapril

Pós-graduação em Ciência e Tecnologia de Materiais - FC

Estudo das lignanas de Peperomia blanda (Piperaceae): abordagem de aspectos estruturais, metabólitos e biossintéticos

Pós-graduação em Química - IQ

Neolignans from fruits of Virola elongata

Fruits of Virola elongata contain, besides the furofuranoid lignans eudesmin, epieudesmin and fargesin, the aryl-benzyl-methyl tetrahydrofuran neolignans magnostellins A and C. The absolute configuration of the magnostellins was detennined.