23 resultados para feasibility


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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Autologous hematopoietic stem cell transplantation is a conduct used to treat some hematologic diseases and to consolidate the treatment of others. In the field of nursing, the few published scientific studies on nursing care and early hospital discharge of transplant patients are deficient. Knowledge about the diseases treated using hematopoietic stem cell transplantation, providing guidance to patients and caregivers and patient monitoring are important nursing activities in this process. Guidance may contribute to long-term goals through patients' short-term needs. To analyze the results of early hospital discharge on the treatment of patients submitted to autologous transplantation and the influence of nursing care on this conduct. A retrospective, quantitative, descriptive and transversal study was conducted. The hospital records of 112 consecutive patients submitted to autologous transplantation in the period from January to December 2009 were revisited. Of these, 12 patients, who remained in hospital for more than ten days after transplantation, were excluded from the study. The medical records of 100 patients with a median age of 48.5 years (19-69 years) were analyzed. All patients were mobilized and hematopoietic stem cells were collected by leukapheresis. The most common conditioning regimes were BU12Mel100 and BEAM 400. Toxicity during conditioning was easily managed in the outpatient clinic. Gastrointestinal toxicity, mostly Grades I and II, was seen in 69% of the patients, 62% of patients had diarrhea, 61% of the patients had nausea and vomiting and 58% had Grade I and II mucositis. Ten patients required hospitalization due to the conditioning regimen. Febrile neutropenia was seen in 58% of patients. Two patients died before Day +60 due to infections, one with aplasia. The median times to granulocyte and platelet engraftment were 12 days and 15 days, respectively, with median red blood cell and platelet transfusions until discharge of three and four units, respectively. Twenty-three patients required rehospitalization before being discharged from the outpatient clinic. The median time to granulocyte engraftment was 12 days and during the aplasia phase few patients were hospitalized or suffered infections. The toxicity of the conditioning was the leading cause of rehospitalization. The nursing staff participated by providing guidance to patients and during the mobilization, transplant and outpatient follow-up phases, thus helping to successfully manage toxicity.

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This study aims to determine physical properties of particleboard made of sawmill waste, as a mix of several wood species, and two adhesives: urea-formaldehyde, usually employed in industry (even with drawbacks or formaldehyde emission during pressing) and FASTBOND®, water based resin, still poorly referenced in literature. Sixteen panels have been produced, in four experimental conditions, defined by using two adhesives and a 12 mm thick limiter (or not). Variance analysis was adopted to evaluate influence of experimental conditions on physical properties of produced panels, manufactured in nominal dimensions 350x350mm; 10% resin related to particles mass (at 5% moisture); 3.5 MPa compaction pressure, temperature 130°C, in a 10 min cycle. Tests to determine density, moisture content, swelling and water absorption were carried out based on normative parameters of ABNT NBR 14810:2006. Results have been satisfactory to panels produced with urea-formaldehyde but those manufactured with polychloroprene based resin (FASTBOND®) not meet regulatory requirements. Best results have been obtained without limiter.

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In the wake of current global image involving environmental impacts, the use of wind power has had a remarkable growth in recent years as a technique for generating electricity. In fact, it is a source featuring strong dissemination of technology which provides decrease in costs and a greater access to low-income electricity. PROINFA (Incentive Program for Alternative Energy Sources) promotes a greater diffusion of new technologies for power generation, in particular wind-produced. Due to such a scenario on the exploitation of such energy source, current analysis discusses strategies for the development of domestic wind technology and the implications for electricity-lacking rural areas. Analysis shows a similar behavior between rural populations lacking electricity and the amount of potential energy available in the region. It is expected that this assay will contribute towards the establishment of public policies for wind-energy parks on rural farms in the North and Northeast regions of Brazil.

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Solar heaters are an appropriate technology in tropical and sub-tropical climates to heat bath water by solar energy. Low-cost solar heaters meet the demand of low-income rural communities which currently do not have access to this technology. Current research analyzes the economic viability of solar heaters, built with recyclable materials, to reduce electric energy bill. A solar heating system was built consisting of recyclable materials in accordance with the manuals provided by the Secretariat of Environment of the state of Paraná (SEMA). Duration of use of electric showers by families of rural properties was determined to calculate expenses and billing of electricity. Simulation and material costs showed that the system was feasible. Commercial solar heaters could be replaced at a cost of R$ 22.61 per month during 13 months.