Deus abençoe a América: religião, política e relações internacionais dos Estados Unidos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A família e a questão da negligência: papéis atribuídos e relações estabelecidas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Responsabilidade do Estado pelos danos às vítimas de crimes

Pós-graduação em Direito - FCHS

Entrincheirados no tempo: a FEB e os ex-combatentes no cinema documentário

Pós-graduação em História - FCHS

O enfrentamento à violência doméstica contra crianças e adolescentes no município de Orlândia-SP: o papel do Conselho Tutelar

Pós-graduação em Serviço Social - FCHS

Percepção de mães sobre vínculo e separação de seus bebês em uma unidade prisional feminina na cidade de São Paulo-SP

Pós-graduação em Psicologia do Desenvolvimento e Aprendizagem - FC

Oral squamous carcinoma cells secrete RANKL directly supporting osteolytic bone loss

Objective: Local invasion of bone is a frequent complication of oral squamous cell carcinoma (OSCC). Development of these osteolytic lesions is mediated by osteoclasts. Receptor activation of NF-kappa B ligand (RANKL) signaling, counteracted by osteoprotegerin (OPG), regulates osteoclastogenesis. Previous studies in rodent models have demonstrated that inhibition of RANKL decreases tumor growth and lesions within bone. However, the contributory role of OSCC cells to this disease process has yet to be defined.Methods: RANKL expression was assessed in a panel of OSCC cell lines by qPCR, flow cytometry, and ELISA. Induction of osteoclastogenesis was assessed by co-culture with macrophages or with OSCC-derived conditioned medium. In an animal model of bone invasion, nude mice were injected intratibially with UMSCC-11B cells expressing a RANKL luciferase promoter to detect tumor-derived RANKL activity. Osteolytic lesions were analyzed by X-ray, micro-CT, and histological methods. RANKL expression was assessed in human OSCC tissues by immunohistochemistry.Results: We demonstrated that OSCCs express varied levels of all RANKL isoforms, both membrane-bound and soluble RANKL. Both co-culture and treatment with OSCC-conditioned media induced osteoclastogenesis. In mice, we demonstrated human RANKL promoter activity during bone invasion. Over the course of the experiment, animals suffered osteolytic lesions as RANKL-driven luciferase expression increased with time. After 8 weeks, human-derived RANKL was detected in areas of bone resorption by immunohistochemistry. Similar epithelial RANKL expression was detected in human OSCC tissues.Conclusion: These data demonstrate the ability of OSCCs to produce RANKL, directly altering the tumor microenvironment to increase osteoclastogenesis and mediate local bone invasion. (C) 2012 Elsevier Ltd. All rights reserved.

O Programa Minha Casa Minha Vida, o mercado imobiliário e o direito à cidade: análise dos impactos do programa na cidade de São Carlos - SP

This article discusses, in general matters, the economic and social motivations, the organization and development of the program Minha Casa Minha Vida, made in 2009, by Federal Government of Brazil. The objective of this work was to analyse the Brazilian economic and housing context, and the program relation with the Subprime international crisis, which has been started at United States in 2008, as well as analysing and discussing the logistics and the program accessibility. The MCMV program, part of the PAC – Programa de Aceleração do Crescimento – has the intention to combat the economic crisis that had been installed and also minimize the deficit housing of the country. From PAC's initial estimate, US$250 Bi, it has been spent US$129 Bi and it has already been approved more than US$125 Bi designated for the second stage of the program, whose the estimate of PAC2 is about one trillion and a half of brazilian reais. One million homes were built between 2009 and 2012, and the goal for 2014 is two million and a half of new residences. If comparing the current program with the oldest programs, progress were observed ,however, problems and inconsistences are clearly seen: in the real concernment, the truly beneficiary, and contradiction between a social and economic program to urban demands, among other situational factors. It’s also evident, the incentivation for a new residential and closed neighbourhoods, thereby adding to the fragmentation of the urban space, beyond of the exclusion socioespacial caused financing of residences in farest allotments. The capitalist production of the space it’s clearly thriving in analysis of thisfinancing package of the urban habitation, where the biggest glebas rise between central neighbourhood and the newest generated suburb, they evidence the negligence of the authorities in well managing the space, not executing the application of urban instruments of planning the social function, and...

A transformação e revalorização do espaço do centro histórico de Santos/SP

The city of Santos always had its importance recognised by the respectful role of flowing off the coffee production between the end of 19th and beginning of 20th centuries. All effervescence of this period brought changes to the central area of the city, located near the port. Beginning in the 1970s, some changes in the politics and in the city's urban space made its cafes, theaters, stores and traditional residencies find itselves in decadence imposed by the negligence of the public power. The Historic Downtown of Santos changed to a forgotten and depreciated space and remained that way for many years, reflecting negatively in the preservation of the arquitetonic heritage of the city. The present project aims to analyse the transformation of the current space of the Hitoric Downtown of Santos from the beginning of the 20th century and its recent revaluation through the public politics of the city

Impacto da saúde bucal na qualidade de vida de adolescentes grávidas

Pós-graduação em Odontologia Preventiva e Social - FOA

Violence against children and adolescents: awareness and attitudes of Brazilian dentists

Violence against children and adolescents, ranging from negligence to sexual abuse, is an imperative public health problem. The ill treatments are considered as nonaccidental traumas, actions or omissions against children, who suffer physical or emotional violence. The main perpetrators are fathers, mothers, guardians, family, friends or the children‘s primary caretaker. It is very important to identify abuse cases, because this allows proper medical and legal intervention. In Brazil, the law n. 8.069, of July 13, 1990, known as the ECA -Statute for Children and Adolescents (SCA), stipulates the obligation to report suspected or confirmed cases of ill treatment against a child or adolescent to the Guardianship Council of the respective locality. The health professionals play a crucial role with regard to identifying cases of violence, collecting information, making early diagnosis of suspect cases and reporting such cases to the authorities. The dentists can contribute significantly, as most injuries occur in the orofacial region. Bite marks, burns, bruising, among others, are easily identified during a dental consultation. The aim of this work was to verify the awareness and attitudes of Brazilian dentists concerning violence against children and adolescents. This research was approved by the Research Ethics Committee of the Faculty of Dentistry of Araraquara – São Paulo State University (FOAr – UNESP). Sixty-three dentists answered an open and closed questionnaire concerning their formation, knowledge, experience and attitudes towards ill-treated children and adolescents. Among other results, thirty-nine dentists (61.9%) affirmed to have the means to identify illtreatment cases, 13 (20.6%) reported having some experience on this matter, but only 8 reported the cases to the Council of Guardianship, as determined by Brazilian law. Twenty percent of the reasons presented for not notifying the Council were fear of reprisal, and 60.0% were uncertain concerning the ethical and legal implications. Physical violence was the most reported form of identified violence (76.9%), followed by negligence (38.5%). Among the 13 professionals that had experience with violence cases, in 10 cases the perpetrators were identified – in 70.0% of the cases, the parents were the originators of such violence. It was concluded that further formation and orientation are necessary, in order to prepare dentists to act correctly when, during their professional activities, they encounter cases of violence against children and adolescents.

The importance of the lifelike esthetic appearance of all-ceramic restorations on anterior teeth

The success of rehabilitation will not depend on just clinical procedures. A proper dental technique (ceramist) is required as well as the respect for some biomimetic principles to obtain the desired final result. This study has the purpose of describing a prosthetic rehabilitation with laminate veneers and all-ceramic crowns of a patient unsatisfied with a previous esthetic treatment because of the negligence of some biomimetic principles. A 45-year-old female patient was admitted to the dental clinic complaining about the lifelike appearance of her all-ceramic restorations. Before the fabrication of new restorations, a mock-up was conducted to verify the patient's satisfaction. A ceramist conducted all the fabrication process so that surface characterizations could be visually verified and the lifelike appearance of natural tooth could be reproduced. After the cementation procedure, the patient reported being satisfied with the lifelike appearance of the new restorations. Based on the clinical findings of the present case report, it can be concluded that the reproduction of the lifelike esthetic appearance of natural teeth and the visualization of the final results before definitive procedures are essential to obtain the clinical success.

Práticas parentais maternas e a influência de variáveis familiares e do bebê

Parenting practices can be understood as the behaviors emitted by parents to educate and socialize their children. The present study investigates the influence of the parenting practices according to the baby sex and age, family configuration and number of children. For this, 50 adult mothers were questioned according to the Parental Styles Inventory for Mothers with Babies (IEPMB). An analysis with the results indicates that mothers with baby girls normally uses a more Positive Monitoring practice when compared with mothers with boy babies. A positive correlation (r = +0.54, p <0.001) was found, between the age of the baby and the practice of negligence, meaning that there is an increase of the usage in the practical as the baby age increases. Also a significant difference (p = 0.04) in the Inconsistent Punishment practice pointed out to the fact that mothers from nuclear families seem to use this practice more than mothers from other family configurations. And multiparous mothers use more Physical Abuse practical than primiparous mothers (p = 0.02). Concerning this analysis, we support a discussion in the present work about the importance of interventions that focus on the effect of specific positive practices, the reduction of negative practices and the role of the network support on the children development.

Soporte social, familiar y autoconcepto: relación entre los constructos

This study aimed at verifying the associations between social support, family support and self-concept in a group of men and women. In the male group there were negative correlations between family support and the factors negligence, aggression and indifference of the instrument of self-concept. In the female group, the total family support was positively correlated with sensuality and accountability, and negatively with uncertainty, and these three measures of the instrument of self-concept. The observed relationships between family support and social support were positive, for both men and women.