33 resultados para Songs (High) with piano.


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The preferred temperature of the yellow scorpion Tityus serrulatus was investigated since its dispersion is a matter of concern. Adult T. serrulatus, weighing 1.24 ± 0.20 g (mean + sd) and with a standard length of 59.3 ± 2.5 mm, were used. A metallic corridor (120 cm long, 5 cm large and 10 cm high) with thermal gradient ranging from 0°C to 40°C was used. Tityus serrulatus chose and stayed in temperatures ranging from 14° C to 38°C when safe conditions were offered (dark and thigmotactic stimuli). The number of animals that remained in the 11°C-20°C, 21°C-30°C, and 31°C-40°C temperature zones were 8, 8, and 9, respectively. The chi-square test (degree of freedom = 2) showed that differences were not significant (p>0.05). Some animals moved to lower temperature areas (less than 8°C) when the corridor was completely illuminated and thigmotactic stimuli were absent, which led the animals to present a torpor state. It is concluded that T. serrulatus does not select a specific environmental temperature. Associated with the capacity of temporally surviving at low temperatures, this species seems to be highly adaptable to different thermal zones.

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The purpose of this study was to identify the drugs most often prescribed for hypertension at the Municipal Health Care Center of the town of Rincäo, State of São Paulo, Brazil, and the principal interactions arising from their association with other drugs, both anti-hypertensives and those in other classes. The study included 725 hypertensive patients registered at this health care center who were regularly seen by a physician every three months. Data were collected on age, sex, occurrence of diabetes, smoking, sedentary lifestyle and overweight, to obtain a profile of the hypertensive population of the area. Control records of all patients were available at the pharmacy in the health care center, where patients obtained their drugs once a month. Of the 725 patients, 38% were male and 62% female. Most (57%) were between 50 and 70 years of age, 21% used tobacco and 43% led a sedentary lifestyle. Single-drug therapy accounted for 33% of the prescriptions, multidrug therapy for 66%. In addition to anti-hypertensives, 50% of the patients took drugs of other therapeutic classes. Of those receiving multidrug therapy, 34% used three or more anti-hypertensives and 66% used only two of these drugs. Drug interactions were detected in as many as 47% of the prescriptions. Captopril was the drug that showed most interactions with others (54%), followed by hydrochlorothiazide (27%), furosemide (14%), propanolol (4%), and nifedipine (1%). The analysis revealed that drug consumption by the patients investigated is high, with a concomitantly high number of episodes of drug interaction.

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Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB

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Pós-graduação em Odontologia Restauradora - ICT

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Pós-graduação em Pediatria - FMB

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB

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Foi estudada a variabilidade espacial da umidade do solo num sistema de irrigação por gotejamento em uma estufa (5,0 x 20,0m) na Fazenda Experimental São Manuel, da Faculdade de Ciências Agronômicas, Universidade Estadual Paulista, Estado de São Paulo, Brasil. Foi estabelecida a malha de amostragem no espaçamento de 1,0 x 0,5m, acrescida de quatro adensamentos de 0,25m. Foram utilizados dados da umidade do solo em 178 pontos. A análise da dependência espacial foi obtida com o auxílio do Programa GS+. Foi construído o variograma experimental e definido o modelo de ajuste, de modo que a curva que melhor se ajustou aos pontos obtidos representasse a magnitude, alcance e intensidade da variabilidade espacial da variável estudada. A umidade do solo apresentou distribuição espacial anisotrópica. Para a direção 0°, pode-se notar uma dependência espacial caracterizada como alta, com o alcance de aproximadamente 3,30m, no sentido do comprimento da estufa. Entretanto, no sentido da largura da estufa, não foi possível ajustar modelos. Utilizando a representação gráfica da superfície, a área estudada apresentou um maior teor de água na parte inicial e menor na parte final das linhas de distribuição de água. A krigagem mostrou-se um bom interpolador para mapeamento da umidade do solo.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Agronomia (Ciência do Solo) - FCAV

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Objective: the objective of this study was to estimate the prevalence of Burnout Syndrome in dentists in the public service in the city of Araraquara – SP and its association with the variables of interest. Material and method: The sample was made up of the dentists active in the public health network (n = 60). Socio-demographic data was collected. The Oldenburg Burnout Inventory (OLBI) was used. Result: Of the participants, 60.0% were female and the average age was 41.9 ± 7.6 years. A large number of the professionals displayed a normal perception of the work conditions, premises, materials and equipment. 63.3% of the individuals feel tired even before arriving for work, 58.3% need more time to relax and to feel better, 70.0% are unable to deal well with the pressures of work, 50.0% feel they have no energy during or after work and 86.7% do not consider the work to be a positive challenge. It was observed that 48.3% of dentists displayed Burnout Syndrome, 11.7% Detachment and 13.3% Exhaustion. There was a significant association between the presence of Burnout and gender (p = 0.020) and the work premises (p = 0.011), with men being the most affected and those that considered the work premises very poor. Conclusion: It was concluded that the prevalence of Burnout Syndrome among dentists is high, with men and those who consider the work premises bad being the most affected.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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The purpose of this study was to determine the effect of PEGylation on the interaction of poly(amidoamine) (PAMAM) dendrimer nanocarriers (DNCs) with in vitro and in vivo models of the pulmonary epithelium. Generation-3 PAMAM dendrimers with varying surface densities of PEG 1000 Da were synthesized and characterized. The results revealed that the apical to basolateral transport of DNCs across polarized Calu-3 monolayers increases with an increase in PEG surface density. DNC having the greatest number of PEG groups (n = 25) on their surface traversed at a rate 10-fold greater than its non-PEGylated counterpart, in spite of their larger size. This behavior was attributed to a significant reduction in charge density upon PEGylation. We also observed that PEGylation can be used to modulate cellular internalization. The total uptake of PEG-free DNC into polarized Calu-3 monolayers was 12% (w/w) vs 2% (w/w) for that with 25 PEGs. Polarization is also shown to be of great relevance in studying this in vitro model of the lung epithelium. The rate of absorption of DNCs administered to mice lungs increased dramatically when conjugated with 25 PEG groups, thus supporting the in vitro results. The exposure obtained for the DNC with 25PEG was determined to be very high, with peak plasma concentrations reaching 5 mu gmL(-1) within 3 h. The combined in vitro and in vivo results shown here demonstrate that PEGylation can be potentially used to modulate the internalization and transport of DNCs across the pulmonary epithelium. Modified dendrimers thereby may serve as a valuable platform that can be tailored to target the lung tissue for treating local diseases, or the circulation, using the lung as pathway to the bloodstream, for systemic delivery.

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Pós-graduação em Medicina Veterinária - FCAV