Morphology of Aortic Arch in Rabbits with Atherosclerosis Treated with Resveratrol

Objective: Atherosclerosis is a chronic inflammatory condition associated with the production of oxidative species. The phenoliccompound, resveratrol, seems to have cardioprotective activities preventing the oxidation of low-density lipoproteins.In this study we investigated the effect of resveratrol on prevention of induced atheromatosis, through the morphological study of the segment of aortic arch in White New Zealand rabbits.Study design: 20 rabbits were divided into four groups which received the following diet for 60 days: control group (CT) normal ration; resveratrol group (R) normal ration and resveratrol (3 mg/kg/day); cholesterol group (CL) 1.5% of cholesterol added to the ration; group cholesterol plus resveratrol (CR) 1.5% of cholesterol added to the ration and resveratrol (3 mg/kg/day). The analysis of the atherosclerotic lesions were performed by the means of appropriate histological techniques.Results and conclusions: The animals belonging to group CL showed atherosclerotic lesions with tunica intima thickening due to the presence of foam cells, placed in several disorganized layers, and extracellular lipid droplets in subendothelial conjunctive tissue.We also observed the invasion of foam cells in the beginning of tunica media. In animals belonging to group CR there were changes in the subendothelial of tunica intima, although in a minor degree of development as for the number of foam cells layers and extracellular lipid droplets. An invasion of foam cells in tunica media was observed in this group. We haven't seen any changes in tunica adventitia in any of the studied groups. There were not evident histological changes in any of the analised tunicas for groups CT and RConclusions: This study may help demonstrate that the phenolic compound, resveratrol, works as a preventive agent in the development of atherosclerotic lesions.

Neuromuscular recovery of the biceps brachii muscle after resistance exercise

The aim of this study was to determine the time to restore the biceps brachii (BB) electromyographic (EMG) activity after the biceps curl (BC) exercise, at different intensities. Ten males performed initially maximal voluntary isometric contractions (MVC) of the elbow flexors, followed by one isometric submaximal contraction at 50% MVC (reference contraction). After this, four bouts of the BC at 25%, 30%, 35%, and 40% 1 RM during 1 minute (randomly assigned, with 10 minutes rest between them) were performed. During the rest intervals at preestablished moments (15 seconds, 1, 3, 5, and 10 min), isometric 50% MVC were performed. The EMG variables (root mean square [RMS], zero crossings [ZC], median frequency, [MF] and peak power [PP]) at rest were compared with reference values. Immediately after the exercise, RMS and PP increased, while ZC and MF decreased, indicating fatigue. After 1 minute most of the variables were similar to the reference. Different load levels did not affect the EMG recovery. In conclusion, the EMG variables recovered after 1 minute rest, indicating the optimal muscular condition for subsequent bouts. Copyright © Taylor & Francis Group, LLC.

Perfil demográfico, sócio-econômico e morbidade referida na população do município de Pratânia, SP

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Portais corporativos: tecnologia da informação e do conhecimento em empresas de tecnologia da informação

Pós-graduação em Ciência da Informação - FFC

Música e idosos: a relação ensino/aprendizagem em três oficinas de música na cidade de São Paulo

Pós-graduação em Música - IA

Avaliação imunofenotípica de subpopulações linfocitárias no sangue do cordão umbilical e periférico de suínos neonatos (Sus scrofa)

Considering the importance of umbilical cord blood as a potential source of stem cell and, on the other hand, the use of the domestic swine (Sus scrofa) as a useful model for biomedical research in regenerative medicine and aiming to contribute about the quantification of lymphocyte subsets in umbilical cord blood and peripheral blood of newborn piglets, this study aimed to quantify CD4+, CD5+ and CD8+ cells from umbilical cord blood and peripheral blood from pigs at term blood samples. Were analyzed samples of the umbilical cord blood and peripheral of 48 piglets of Topigs lineage, from healthy mothers, artificially inseminated and natural birth. Blood samples were collected from the umbilical cord at birth, by the umbilical vein, and peripheral blood by venous sinus retro-ophthalmic. The immunological measurements of CD4+, CD5+ and CD8+ were obtained by flow cytometry. The relative average values for the CD4+, CD5+ e CD8+ counts in umbilical cord blood and peripheral blood of newborn piglets were inferior to those reported for peripheral blood in adult pigs, suggesting immunological immaturity. The ratio CD4+:CD8+ in umbilical cord blood (3.2±1.2%) and peripheral blood (3.2±1.7%) showed a predominance of TCD4+ over TCD8+. The percentage of CD4+ and CD8+ cells was 1.37±0.86% and 1.15±0.57%, respectively, in umbilical cord blood and peripheral blood.

Biologia pulpar: da agressão à reparação

The study of the dental pulp can be extended from factors related to its aggression to those related to new concepts of regeneration. The purpose of this compilation of studies is to present the evolution of a research subject from damage to repair. Innitially, studies will demonstrate the ability of dental procedures to generate heat and consequently affect the dental pulp. In sequence, studies will also present some effects of different pulp capping materials on dental pulp cells, related to the cytotoxicity of these materials and inflammatory potential. Finally, as the subject is emmerging and gaining importance in the literature, this compilation will present data from recent studies on the role of dental pulp progenitor cells in the regeneration and repair of dental pulp, as well as an alternative for a scaffold that could be used for clinical translation of research in the field. In summary, dentists must be aware of these different aspects and that the knowledge on factors and mechanisms involved in the aggression of the dental pulp can also serve as basis for understanding aspects for regeneration.

Hiperatividade: o que acontece na sala de aula?

Hyperactivity has been frequently discussed, researched and monitored, but it is important to investigate the student, the interrelationships that exist in the classroom and everything that happens in that context, what are the difficulties, facilities and behaviors. The intention of this work contribute to the education, seeking answers to the questions about hyperactivity and what happens in the classroom, or that was the object of study: classroom and its dynamics. This is a field study aimed to analyze the educational aspects and inter-personal relationship student-student and studentteacher in an inclusive classroom where there is a student with hyperactivity properly diagnosed. It was proposed to draw a profile of the hyperactive student, since it constitutes a case study. The research subject was a student of 3rd year of elementary school to public school, clinically diagnosed as hyperactive and who is backed by family, school and doctor. For data collection was developed an observation protocol, completed daily. The student was observed for two months on alternate days and times, totaling 18 classes. Interviews were conducted with the teacher and the student's mother in order to profile the student participant. After compiling the data, we can find the answers of the questions that motivated this research, it is possible to identify the unpreparedness of teachers to deal with hyperactive students in the classroom, the spread of behaviors, considering many students as hyperactive, but no diagnosis; need to adapt the content, but properly and not just recreational; lack of dialogue between school and family

Ética, educação e experiência formativa na temporalidade do presente

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Relações de gênero e sexualidade na educação infantil: interfaces que envolvem as práticas pedagógicas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Superdotação e criatividade: análise de dissertações e teses brasileiras

Pós-graduação em Educação para a Ciência - FC

A mini review of Candida species in hospital infection: epidemiology, virulence factor and drugs resistance and prophylaxis

The introduction of more efficient diagnostic methods, new techniques in surgery and transplantation, antibiotics and chemotherapeutics more potent and novel materials for prostheses, catheters and probes significantly increased the life expectancy and quality of life of critically ill patients, on the other hand, hospital-acquired infections emerged as important iatrogenic complications. Invasive infections are a growing problem in public health hospitals in Brazil and worldwide. Among the various etiological agents found in the hospital environment, the genus Candida has been the third most frequently isolated pathogen. In general, invasive fungal infections are associated with high morbidity and mortality, difficulties in diagnosis, antimicrobial resistance, length of hospital stay and increased hospital costs. This mini review of the literature describes about epidemiology of hospital infection of Candida species, as well as its virulence factors and drugs resistance

A pesquisa em psicologia: ensaio sobre a Psicologia enquanto ciência, a pesquisa qualitativa e o uso da entrevista como principal instrumento de coleta de dados

For constituting itself a science, Psychology has coursed along way. From the time he was considered a Philosophy’s discipline until to be recognized as a legitimate science, Psychology had to devoteto the definition of its object of study, the development and refinement of theoretical-methodological frameworks and, in particular, to consolidation process of their research strategies and knowledge construction. Therefore, in order to regard the demands of the classical scientific paradigm, which is very influenced by Positivism, Psychology made use, initially, of quantitative methodology and laboratory research. This article presents some of the process of identity construction of Psychology as a science, focusing on its transition path between the quantitativist paradigm of scientific knowledge production to the qualitativist paradigm, until that is more commonly practiced nowadays: the collaborative use of these methodological strategies. For presenting the qualitative researching Psychology, we discussed, beyond its proposal and differentiation elements in relation to quantitative research, the different methods used for this mode and, in particular, the interview - which is considered the main way of data collection in surveys conducted by psychologists and, therefore, it is an important element the process of knowledge building that science, in addition to being the most qualified space for dialogue between there searcher and the research subject.

Classification of handwriting patterns in patients with Parkinson´s disease, using a biometric sensor

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Entre choques, cortes e fissuras - a (semi)formação estética: uma análise crítica da apropriação de filmes na educação escolar

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)