Estudo de perfil de dissolução dos medicamentos de referência, genérico e similar contendo cefalexina na forma farmacêutica cápsula

With recent advances in technology and research into drug delivery, the modernization of tests and greater emphasis on the predictability of therapeutic effect by means of in vitro tests, the dissolution test and the study of dissolution profiles are gaining more and more importance. Though introduced initially as a way of characterizing the release profile of poorly soluble drugs, dissolution tests are currently part of pharmacopoeial monographs on almost all the oral solid pharmaceutical forms. The objective of this study was to determine the dissolution profile (percent drug dissolved versus time) of the pioneer brand, generic and similar pharmaceutical capsules containing 500mg cephalexin. Three pharmaceutical brands (reference, generic and similar) were subjected to the dissolution test and in vitro dissolution profiles were recorded. From the results of the dissolution test, it was concluded that the samples met the acceptance criterion, as no difference was observed in the percentage of the drug dissolved in a standard time. The dissolution profile indicated that this medicine, in this pharmaceutical form, dissolves readily (85% of the drug dissolved in 15 minutes) and the curves showed great similarity, suggesting that the 3 brands are pharmaceutically equivalent.

Bibliotecas, arquivos e museus como centros de referência na dimensão cultural das comunidades

With the evolution of the organizations theory, new management practices have transformed the institutions. The improvement of these management practices in cultural unities (UCs) is constant, and interacts in the international axis, since each unity increasingly communicate with other. As a reflection of organizational administrative practices, UCs had developed and assumed the organizational theories to make easy a framework for effective management practices. Comprehending the importance of the studies on UCs requires both a new approach of existing public politics for this field, and the recognition of the Information Science knowledge on area. In this way, it was planned to develop a model constituting a tool for managers in these institutions through the experience of laboratory works carried out with researchers from the European community. Libraries and museums are institutions that operate in the social process of their communities and the archives establish their structural spaces in parallel with the political, economic and social environments of the communities, translate the society and its organic sphere of informational performance. The information transposes a cyclical and essential role for the arrangement of the effective and necessary record to the organizational process and the institutional growth. Studies of this nature contribute to value a economy based on knowledge, and its production emphasizes the human capital that permeates the condition of the information in support for the development of communities and the growth of the organizational environment in political, social and cultural spheres.

Estimativa da evapotranspiração de referência com uso do Irrigâmetro em Vitória da conquista/BA

The Irrigameter is aevapotranspiration measuring device used in irrigation management to optimize water. However, its use requires a prior adjustment to weather conditions where it will be used. The objective of this study was identify the corresponding height of water level inside the evaporimeterIrrigameter that estimate reference evapotranspiration in climate of the plateau of Vitoria da Conquista - BA, in different seasons. The experiment was a completely randomized design with five treatments and three replications. For each treatment was determined an average coefficient for the Irrigameter called K I, calculated as the ratio of estimated evapotranspiration in Irrigameter (ET I) and reference evapotranspiration (ET 0). The ET 0 was obtained by the Penman-Monteith - FAO 56. The results showed that the coefficients of Irrigameter increased exponentially with increasing water level inside the evaporimeter, and the equipment must be operated with the water level equal to 5.2 cm for better estimation of ET 0. The remaining heights observed in different seasons showed no significant difference when compared to annual average used as a reference in this study.

Projeto de uma referência de tensão com baixa susceptibilidade a interferência eletromagnética (EMI)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Análise de três métodos de estimativa da evapotranspiração de referência para a região de Pradópolis - SP

Pós-graduação em Agronomia (Ciência do Solo) - FCAV

Uso de um objeto de aprendizagem no ensino de ciências tomando-se como referência a teoria sócio-construtivista de Vygotsky

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Dryinidae (Hymenoptera, Chrysidoidea) de áreas de preservação da Mata Atlântica do estado de São Paulo, com especial referência a Dryinus Latreille

Pós-graduação em Agronomia (Entomologia Agrícola) - FCAV

Distribuição geográfica e características demográficas da doença trofoblástica gestacional em centro de referência terciária do Estado da Bahia, Brasil

Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB

Análise de linguagens de modelagem de processos de um modelo de referência na cadeia de suprimentos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Serviço de referência e informação para smartphones: análise de acesso e uso

Pós-graduação em Ciência da Informação - FFC

Serviço de referência digital: uma análise apoiada em agentes de interface

Pós-graduação em Ciência da Informação - FFC

Valores de referência de cortisol salivar para a avaliação adrenal em crianças menores de três anos, sem patologias

Pós-graduação em Pediatria - FMB

O sistema de referência e contrarreferência na estaratégia saúde da família no município de Bauru: perpectivas dos gestores

Pós-graduação em Enfermagem (mestrado profissional) - FMB

O sistema de referência e contra-referência no atendimento ao adolescente infrator: percepção dos profissionais de saúde da Fundação CASA

Pós-graduação em Enfermagem (mestrado profissional) - FMB

Problematizando a violência doméstica contra a criança no Centro de Referência da Assistência Social (CRAS)

Pós-graduação em Psicologia - FCLAS