Relevância do assited hatching com laser em um programa de ovo-doação utilizando banco de óvulos criopreservados: Um estudo prospectivo randomizado

Objective: This prospective randomized trial evaluated if there is an improvement in clinical outcomes when assisted hatching is performed in embryos derived from vitrified oocytes in an ovum donation program. Methods: Sixty oocyte recipients undergoing donation program using egg-cryobanking were randomly allocated to the assisted hatched (AH, n=30) or control group (n=30). Pregnancy and implantation rates were compared between the groups. Vitrification and warming procedure were carried out according to the Cryotopmethod. Immediately before embryo transfer, embryos undergoing laser-assisted hatching had the zona pellucida thinned using a 1.48 μm wavelength diode laser. Results: A total of 288 vitrified MII oocytes were warmed for the 60 recipients (4.8 oocytes per recipient). Out of 288 vitrified oocytes, 273 (94.8%) survived. All surviving oocytes were sperm injected and 228 displayed 2 pronucleus 16-18h after injection (83.5%). There were 172 good quality embryos transferred. Twenty four patients achieved clinical pregnancy (total pregnancy rate of 40%). The clinical pregnancy rate did not differ between AH and control groups (44.4% and 33.3%, respectively, p=0.1967), however AH resulted in a significant higher implantation rate (31.6% and 18.4%, p=0.0206). These findings were confirmed by the regression models either for pregnancy (OR = 1.14; IC 95% = 0.80-.72; p= 0.766), as for the implantation rate (RC:19.45, P=0.041). Conclusions: Our evidences demonstrated the effectiveness of the AH in embryos derived from warmed oocytes and suggest that oocyte cryopreservation is a valuable tool to provide successful outcomes in an egg donor program. © Todos os direitos reservados a SBRA - Sociedade Brasileira de Reprodução Assistida.

Perfil, ações e relações dos agentes comunitários de saúde integrantes do Programa de Saúde da Família do município de Araçatuba-SP

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O trabalho com grupos no programa saúde da família na perceção dos pacientes participantes: criando redes de ajuda e construindo cidadania

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Liberdade de expressão e discurso do ódio: um exame sobre as possíveis limitações à liberdade de expressão

In a view to determining the outlines of the Freedom of Speech and to specify its contents, we face hate speech as an offensive and repulsive manifestation, particularly directed to minority groups in contemporary society. Thus, the study sought to promote, in the foreground, a study of the Freedom of Speech, in the liberal molds. Considered this way, Freedom of Speech will tend to accept hate speech as a legitimate manifestation, albeit at the injury of the victims. On the other hand, when we are dealing with the exhaustion of the liberal paradigm and the affirmation of the Welfare State, we note the recognition by the social state of the asymmetries and commitment to redistributive justice. The Freedom of Speech, warded by welfare state will tend to suffer major restrictions on its self-determination power, rejecting hate speech.

Escrita e Liberdade: as relações de causa e consequência na expressão discente

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)