127 resultados para Polinómios matriciais
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Pós-graduação em Matematica Aplicada e Computacional - FCT
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Pós-graduação em Matematica Aplicada e Computacional - FCT
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Pós-graduação em Matematica Aplicada e Computacional - FCT
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Pós-graduação em Matematica Aplicada e Computacional - FCT
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Pós-graduação em Matemática em Rede Nacional - IBILCE
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Oral administration is widely accepted route for drug delivery and solid dosage forms are commonly employed. The variation of absorption profiles along the human gastrointestinal tract (GIT) and the ability to target drugs by adequate dosage forms to distinct sites is the challenge in the pharmaceutical development of solid dosage forms. AC Biosusceptometry (ACB) is a technique that deserves consideration due to its features, accuracy of results and versatility. The purpose of this work was to evaluate, by employing the AC Biosusceptometer, the rate of swelling of systems matrices consisting of hydrophilic polymer (hydroxypropyl methyl cellulose) and magnetic material. Matrices tablets were evaluated in vitro to a more detailed analysis of kinetics of swelling, in addition to the study and application of mathematical models to correlate the magnetic area variation and the water uptake. All the procedures for qualitative and quantitative analysis of digital signals as well as the magnetic images processing were performed in MatLab® (Mathworks Inc.). ACB technique proved to be useful towards estimating the swelling properties of hydrophilic matrices in vitro, showing a promising capacity for further analyses involving dissolution test and in vivo studies, supporting their innovative potential pharmaceutical applications
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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With the advance of mathematical methods throughout the centuries, in particular with respect to the differential calculus, the notion of fractional derivative emerged with Leibniz and later developed by several well known scientists. Today that formalism is well used in the study of diffusion phenomena among other areas. We extend the fractional indices to matricial indices and develop a formalism to handle this generalized derivative, as well as other operators, functions and functionals in mathematical physics, originally defined for natural indices. Here we only consider 2x2 hermitian and anti-hermitian matrices. These matrices are associated to the well known Pauli matrices and Hamilton's quaternions. Applications with mathematical physics functions are presented
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Pós-graduação em Engenharia Elétrica - FEB