Action of ethanolic extract from aerial parts of Tagetes patula L. (Asteraceae) on hatchability and embryogenesis of Rhipicephalus sanguineus eggs (Acari: Ixodidae)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Late Quaternary vegetation dynamics from central parts of the Madeira River in Brazil

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Trajectory and outcomes of speech language therapy in the Prader-Willi syndrome (PWS): case report

The aim of this study was to describe the trajectory and the outcomes of speech-language therapy in Prader-Willi syndrome through a longitudinal study of the case of an 8 year-old boy, along four years of speech-language therapy follow-up. The therapy sessions were filmed and documental analysis of information from the child's records regarding anamnesis, evaluation and speech-language therapy reports and multidisciplinary evaluations were carried out. The child presented typical characteristics of Prader-Willi syndrome, such as obesity, hyperfagia, anxiety, behavioral problems and self aggression episodes. Speech-language pathology evaluation showed orofacial hypotony, sialorrhea, hypernasal voice, cognitive deficits, oral comprehension difficulties, communication using gestures and unintelligible isolated words. Initially, speech-language therapy had the aim to promote the language development emphasizing social interaction through recreational activities. With the evolution of the case, the main focus became the development of conversation and narrative abilities. It were observed improvements in attention, symbolic play, social contact and behavior. Moreover, there was an increase in vocabulary, and evolution in oral comprehension and the development of narrative abilities. Hence, speech-language pathology intervention in the case described was effective in different linguistic levels, regarding phonological, syntactic, lexical and pragmatic abilities.

Statistical detection of spurious variations in daily raingauge data caused by changes in observation practices, as applied to records from various parts of the world

In the instrumental records of daily precipitation, we often encounter one or more periods in which values below some threshold were not registered. Such periods, besides lacking small values, also have a large number of dry days. Their cumulative distribution function is shifted to the right in relation to that for other portions of the record having more reliable observations. Such problems are examined in this work, based mostly on the two-sample Kolmogorov–Smirnov (KS) test, where the portion of the series with more number of dry days is compared with the portion with less number of dry days. Another relatively common problem in daily rainfall data is the prevalence of integers either throughout the period of record or in some part of it, likely resulting from truncation during data compilation prior to archiving or by coarse rounding of daily readings by observers. This problem is identified by simple calculation of the proportion of integers in the series, taking the expected proportion as 10%. The above two procedures were applied to the daily rainfall data sets from the European Climate Assessment (ECA), Southeast Asian Climate Assessment (SACA), and Brazilian Water Resources Agency (BRA). Taking the statistic D of the KS test >0.15 and the corresponding p-value <0.001 as the condition to classify a given series as suspicious, the proportions of the ECA, SACA, and BRA series falling into this category are, respectively, 34.5%, 54.3%, and 62.5%. With relation to coarse rounding problem, the proportions of series exceeding twice the 10% reference level are 3%, 60%, and 43% for the ECA, SACA, and BRA data sets, respectively. A simple way to visualize the two problems addressed here is by plotting the time series of daily rainfall for a limited range, for instance, 0–10 mm day−1.