Factor XIII Val34Leu is a genetic factor involved in the aetiology of venous thrombosis

A mutation in the factor XIII gene (FXIII Val34Leu) gene was recently reported to confer protection against myocardial infarction, but its relationship with venous thrombosis is unknown. In addition, a mutation in the 5'-untranslated region of the FXII gene (46 C→T) was identified which is associated with low plasma levels of the protein. Its prevalence in patients with venous thrombosis is also unknown. We investigated the frequency of the FXIII Val34Leu and FXII 46 C→T mutations in 189 patients with deep venous thrombosis and in 187 age-, gender- and race-matched controls. FXIII Val34Leu was detected in 38.6% of the patients and in 41.2% of the controls. Interestingly, homozygosity for the FXIII mutation was found in 1.6% of the patients and in 9.6% of the controls. yielding an odds ratio (OR) for venous thrombosis of 0.16 (95% CI: 0.05-0.5). The OR for heterozygotes was 1.1 (95% CI: 0.7-1.7). The FXII 46 C→T mutation was detected in 46.0% of the patients and in 48.6% of the controls. The OR for heterozygotes was 0.9 (95% CI: 0.6-1.4) and for homozygotes the OR was 0.8 (95% CI: 0.3-1.9). Our data indicate that the FXII 46 C→T mutation is unlikely to be a major risk factor for venous thrombotic disease. In contrast, the homozygous state for FXIII Val34Leu is a strong protective factor against venous thrombosis, which emerges as a novel generic factor involved in the aetiology of thrombophilia.

Daños causados por cancro cítrico en la producción de naranja dulce 'Valencia'

The citrus canker, caused by Xanthomonas axonopodis pv. citri, is one of the main citrus diseases and has threatened the world's citriculture. In this study, the damage caused by citrus canker was quantified in a sweet orange culture, cv. Valencia [Citrus sinensis (L.) Osb.], grafted over 15 year-old Rangpur lime (C. limonia Osb.), in the municipality of Guatambu, SC, Brazil, in the crop of 2004/05. Evaluations of the number of fruits per plant (NF), fruit yield per plant (P), citrus canker incidence on the fruit (IFR), and incidence (IL) and severity (SV) of citrus canker on 80 leaves per orange tree were performed in the harvest period, applying diagrammatical scales. Plants had large variation in SV (0.16%-1.09%), IL (12.50%-56.25%) and IFR (12.30%-56.09%). Linear regressions were significant between IL x SV, NF x SV, P x IFR, and NF x IFR. There was no significant difference (p>0.05) between the mean estimated values of IL in different quadrants of the crowns of the orange trees (N, S, L and O). Each 1% increase in IFR reduced 2.16 kg and 21.3 fruits per tree.

A sacralidade das realezas castelhana e portuguesa nos relatos cronísticos ibéricos dos séculos XIV e XV

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A escrita do passado entre monges e leigos (Portugal - séculos XIV e XV)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Da Quanta cura (1864) de Pio IX a Rerum novarum (1891) de Leão XIII: relações entre permanências e busca por adaptações

Pós-graduação em História - FCLAS

Autoridade e poder: os limites do poder temporal e espiri- tual no século XIV, segundo o pensamento de Guilherme de Ockham

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O despojamento em São Bernardo de Claraval e São Francisco de Assis (séculos XII e XIII)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A traição na canção de Gesta Renaut de Montauban: herança neotestamentária, ética cavaleiresca e evolução política na França do século XIII

Pós-graduação em História - FCLAS

Centro de educação matemática (CEM): fragmentos de identidade

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Boosted objects and jet substructure at the LHC. Report of BOOST2012, held at IFIC Valencia, 23rd-27th of July 2012

This report of the BOOST2012 workshop presents the results of four working groups that studied key aspects of jet substructure. We discuss the potential of first-principle QCD calculations to yield a precise description of the substructure of jets and study the accuracy of state-of-the-art Monte Carlo tools. Limitations of the experiments' ability to resolve substructure are evaluated, with a focus on the impact of additional (pile-up) proton proton collisions on jet substructure performance in future LHC operating scenarios. A final section summarizes the lessons learnt from jet substructure analyses in searches for new physics in the production of boosted top quarks.

Do varão casado a um reino virtuoso (Portugal - sécs. XIV-XVI)

Pós-graduação em História - FCHS

As vogais postônicas do século XIII: um olhar sobre a escrita da época

This work aims to obtain a phonological description of unstressed word-final vowels of Medieval Portuguese (MP). The corpus of this research is comprised of Alfonso X’s Cantigas de Santa Maria, composed on the second half of the 13th century. This work maps all the graphemes that represent, in the corpus considered, the unstressed word-final vowels. From the analyses of writing and rhymes in Alfonso X’s Cantigas de Santa Maria, it was possible obtain some important information about the realization of the unstressed wordfinal vowels in MP.

Un passo indietro al Decameron e os limites intangíveis do Novellino

The narratives of Decameron, composed by Giovanni Boccacio in the 14th century, possess a popular content carefully tied together by a formal structure capable of concentrating sophisticated techniques. The present paper revisits some relation possibilities between Decameron and Novellino, an anonymous work from the 13th century, composed on the basis of fables and stories gathered mainly from the oral tradition. Our aim is not to demonstrate a genealogy of the prose and of its freedom to recover narrative situations but to reflect, by means of examples of great reverberation, on the strategies developed to make elements from the ancient tradition highly functional in the literary tradition, according to the formal resources available in each period.

Aspectos do amor no Roman de la Rose de Guillaume de Lorris e Jean de Meun (Século XIII)

Pós-graduação em História - FCLAS