Osseointegration of implants with dendrimers surface characteristics installed conventionally or with Piezosurgery®. A comparative study in the dog

Aim: The first aim of the present experiment was to compare bone healing at implants installed in recipient sites prepared with conventional drills or a piezoelectric device. The second aim was to compare implant osseointegration onto surfaces with and without dendrimers coatings. Material and Methods: Six Beagles dogs were used in this study. Five implants with two different surfaces, three with a ZirTi® surface (zirconia sand blasted, acid etched), and two with a ZirTi®-modified surface with dendrimers of phosphoserine and polylysine were installed in the right side of the mandible. In the most anterior region (P2, P3), two recipient sites were prepared with drills, and one implant ZirTi® surface and one coated with dendrimers implants were installed at random. In the posterior region (P4 and M1), three recipient sites were randomly prepared: two sites with a Piezosurgery® instrument and one site with drill and two ZirTi® surface and one coated with dendrimers implants installed. Three months after the surgery, the animals were sacrificed for histological analysis. Results: No complications occurred during the healing period. Three implants were found not integrated and were excluded from analysis. However, n = 6 was obtained. The distance IS-B at the buccal aspect was 2.2 ± 0.8 and 1.8 ± 0.5 mm, while IS-C was 1.5 ± 0.9 and 1.4 ± 0.6 mm at the Piezosurgery® and drill groups, respectively. Similar values were obtained between the dendrimers-coated and ZirTi® surface implants. The BIC% values were higher at the drill (72%) compared to the Piezosurgery® (67%) sites. The BIC% were also found to be higher at the ZirTi® (74%) compared to the dendrimers-coated (65%) implants, the difference being statistically significant. Conclusion: This study has revealed that oral implants may osseointegrate equally well irrespective of whether their bed was prepared utilizing conventional drills with abundant cooling or Piezosurgery®. Moreover, the surface coating of implants with dendrimers phosphoserine and polylysine did not improve osseointegration. © 2012 John Wiley & Sons A/S.

Guided implant surgery: What is the influence of this new technique on bone cell viability?

Purpose: To evaluate the effect of implant osteotomy on immediate bone cell viability, comparing guided surgery for implant placement with the classic drilling procedure. Materials and Methods: For this study, 20 rabbits were used. The animals were divided into a guided surgery group (GG) and a control group (CG) and were then divided into 4 subgroups - subgroups 1, 2, 3, and 4 - corresponding to drills used 10, 20, 30, and 40 times, respectively. All animals received 5 osteotomies in each tibia, by use of the classic drilling procedure in one tibia and guided surgery in the other tibia. The osteotomized areas were removed and processed immunohistochemically for detection of osteocalcin, receptor activator of nuclear factor κB ligand (RANKL), osteoprotegerin (OPG), and caspase 3. Results: Immunohistochemical analysis showed that osteocalcin expression was initially higher in the CG and remained constant after drill reutilization. Although the expressions of RANKL and OPG were not statistically different for the GG and CG, the RANKL/OPG ratio tended to be higher for the GG. Moreover, caspase 3 expression was elevated in the GG, proportionally to the number of osteotomies, indicating an increase in the apoptosis index in the GG. Conclusions: The classic drilling procedure is more favorable to cell viability than guided surgery.© 2013 American Association of Oral and Maxillofacial Surgeons.

Avaliação comparativa da viabilidade celular imediata após osteotomia para implantes com fresas e piezocirurgia em tíbias de coelhos: análise imunoistoquímica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Influência da técnica cirúrgica guiada para implantes sobre o aquecimento ósseo, a viabilidade celular imediata e a deformação de fresas após osteotomia para implantes

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação do aquecimento ósseo, da viabilidade celular imediata e da deformação de fresas de alta resistência após osteotomia para implantes em tíbias de coelhos

Pós-graduação em Odontologia - FOA

Deposição e qualidade de sementes de sorgo utilizando um mecanismo dosador de fluxo contínuo

Pós-graduação em Agronomia (Energia na Agricultura) - FCA

Modelagem do escoamento transiente ao longo de trocadores de calor tubo capilar-linha de sucção

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Construção participativa de conhecimentos sobre resíduos no Programa de Coleta Seletiva da Unesp-Bauru: reflexões e ações

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo em suínos sobre osteotomia com brocas de alta e baixa rotação e refrigeração líquida: análise radiográfica digital densitométrica em tecido ósseo alveolar

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Osteotomia com brocas de alta e baixa rotação, com e sem refrigeração líquida: estudo histopatológico duplo cego em suínos

Pós-graduação em Odontologia - FOA

Estudo e caracterização do processo de usinagem do compóstio GLARE

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação de substitutos ósseos em defeitos peri-implantares criados em coelhos

Pós-graduação em Odontologia - FOA

Reparação óssea após osteotomia com brocas de alta e baixa rotação e refrigeração líquida: estudo histológico comparativo entre tecido ósseo alveolar e extra-alveolar em suínos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Profundidade de polimerização de cimentos resinosos utilizados na cimentação de pinos translúcidos e sua influência sobre a resistência adesiva antes e após ciclagem mecânica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Influence of Implant Drill Materials on Wear, Deformation, and Roughness After Repeated Drilling and Sterilization

Purpose:The aim of this study was to evaluate deformation, roughness, and mass loss of stainless steel, diamond-like carbon (DLC)-coated and zirconia drills after multiple osteotomies with sterilization procedures.Materials and Methods:Drilling procedures were performed using stainless steel (G1), DLC-coated (G2), and zirconia (G3) drills. All groups were divided in subgroups 1, 2, 3, 4, and 5, corresponded to drills used 0, 10, 20, 30, and 40 times, respectively.Results:No significant differences in mass and roughness were detected among all groups and subgroups. In SEM images, all groups revealed signs of wear while coating delamination was detected in G2. Drills from G1 displayed more irregular surface, whereas cutting edges were more regular in G3.Conclusion:Zirconia drills presented more regular surfaces whereas stainless steel drills revealed more severe signs of wear. Further studies must be performed to evaluate the putative influence of these findings in heat generation.