Avaliação fitoquímica e microbiológica da espécie Artemisia annua L., submetida a tratamentos de armazenamento e condições de ambiente

Pós-graduação em Agronomia (Energia na Agricultura) - FCA

Caracterização histoquimica de folhas de mentas infectadas por Puccinia menthae e Erysiphe biocellata

Pós-graduação em Agronomia (Horticultura) - FCA

Ocorrência de resistência de Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) à ivermectina administrada em bovinos de São paulo e Minas Gerais, Brasil

Pós-graduação em Medicina Veterinária - FCAV

Análise dos compostos flavorizantes da cana-de-açúcar e otimização da aplicação de extratos ricos em β-glicosidases para liberação de aroma na produção de aguardente de cana

Pós-graduação em Química - IBILCE

Avaliação química e biológica de fungos endofíticos associados à alga marinha Padina gymnospora

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Resistência de Haemonchus placei, Cooperia punctata e Oesophagostomum radiatum à ivermectina pour-on a 500mcgkg-1 em rebanhos bovinos no Brasil

The broad spectrum of endectocides and the easy use mode of their pour-on formulations are factors that have stimulated a higher frequency of use these drugs in cattle. In this study was evaluated the efficacy of ivermectin pour-on using the dose of 500mcgkg(-1), against nematodes in naturally infected cattle from different herds. Twelve calves were brought from each of the four farms selected. All the 48 calves used showed mean of eggs per gram of feces (EPG) greater than 500 considering three consecutive counts. Subsequently, animals from each herd were divided into two groups of six animals each, one treated pour-on with ivermectin 500mcgkg(-1) and other kept as untreated control. Calves were euthanized 14 days after treatment for counting the endoparasites. Ivermectin showed null effect against H. placei in all the herds evaluated. The drug was also ineffective against C. punctata in the herds from Jaboticabal, SP and Formiga, MG, and reached efficacy of 75.8% and 58.4% in herds from Sao Jose do Rio Pardo, SP and Sao Sebastiao do Para so, MG, respectively. Efficacies of 94.2% (Jaboticabal), 0.0% (Sao Jose do Rio Pardo), 94.2% (Formiga) and 39.2% (Sao Sebastiao do Para so) were detectedagainstO. radiatum. Based on these results obtained on the present study, the four populations of Haemonchus placei and Cooperia punctata evaluated were resistant to ivermectin pour-on using a dose of 500mcgkg(-1). Ivermectin-resistant strains of Oesophagostomum radiatum were found in two of the four herds evaluated.

Efficacy of fipronil (1.0 mg/kg) against Rhipicephalus (Boophilus) microplus strains resistant to ivermectin (0.63 mg/kg)

The present study aimed to evaluate the efficacy of fipronil (1 mg/kg) against three strains of ivermectin-resistant Rhipicephalus (Boophilus) microplus (R. (B.) microplus), naturally infesting cattle from different states of Brazil. Three rural properties with a history of macrocyclic lactones ineffectiveness against the cattle tick, and low frequency use of fipronil in the herd, were selected for the study. The animals were randomized according to the mean tick counts, performed on days 3, 2 and I, into three groups with 10 animals each: T01, control (saline solution); T02, subcutaneous ivermectin (0.63 mg/kg) and T03, topical fipronil (1 mg/kg). Treatment was performed on day 0. Counts of partially engorged female ticks were performed on days 3,7 and 14 post-treatment (DPT), and then every 7 days until the 49th DPT. In all three experiments, it was possible to diagnose resistance of R. (B.) microplus to ivermectin (0.63 mg/kg). The maximum efficacy (arithmetic mean) obtained for ivermectin was 64% in experiment II. On the other hand, the formulation containing fipronil (1 mg/kg) reached high efficacy values (>= 97%) in all three experiments. The results from all experiments in this study demonstrate the high efficacy of 1 mg/kg fipronil, administered pour-on in naturally infested cattle, against strains of R. (B.) microplus that are resistant to 630 mcg/kg ivermectin. (C) 2014 Elsevier B.V. All rights reserved.

Aspectos do controle de resíduos de avermectinas no abate de bovinos

Pós-graduação em Medicina Veterinária - FCAV

Caracterização morfológica, perfil químico, atividade biológica e conservação in situ do gênero Lychnophora Mart. (Asteraceae: Vernonieae: Lychnophorinae), Brasil

Many people who live in the cerrado regions use plant species for therapeutic purposes. However, due to intensive extraction of some species, native botanical populations are at risk of disappearing or suffering a dramatic decrease, such as, for instance, individuals of the Lychnophora genus. This has 24 species distributed into the categories vulnerable, endangered, critically endangered, and possibly extinct. These individuals are known in folk medicine as “arnica” and their leaves and flowers are commonly used as anti-inflammatory, analgesic, and healing agents. The chemical profile of the genus is characterized by the presence of sesquiterpene lactones, sesquiterpenes, diterpenes, triterpenes, flavonoids, steroids, polyacetylenes, and caryophyllene derivatives which also have lignans with analgesic activity. Studies with Lychnophora species show significant results with regard to their biological activities against Leishmania amazonensis, Staphylococcus aureus, and Tripanosoma cruzi. Therefore, this study aimed to perform a survey of the morphology, chemical composition, and biological activity, as well as the use and current conservation status of the Lychnophora genus in Brazil.