Tissue engineering: Using collagen type i matrix for bone healing of bone defects

Among the many tissues in the human body, bone has been considered as a powerful marker for regeneration and its formation serves as a prototype model for tissue engineering based on morphogenesis. Therefore, collagen type I is one of the most useful biomaterials used in tissue engineering as extracellular matrix components capable to promote bone healing. The literature reveals excellent biocompatibility and safety due to its biological characteristics, such as biodegradability and weak antigenicity, making collagen type I the primary resource in medical applications. Thus, it was also used for tissue engineering including skin replacement, bone substitutes, and artificial blood vessels and valves. The authors describe the treatment of an abscessed apical periodontal cyst and show good outcomes of bone healing, using tissue engineering, as collagen type I matrix. © 2013 by Mutaz B. Habal, MD.

Continuum psicofísico: uma abordagem baseada no pensamento de Charles S. Pierce

Pós-graduação em Filosofia - FFC

Sistema de coleta, análise e detecção de código malicioso baseado no sistema imunológico humano

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Uma aproximação didática por meio da história do conceito de circulação sanguínea

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O laboratório de anatomia sob a perspectiva da 'descrição densa': interfaces da cultura e o ensino de Ciências

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo de um modelo dinâmico para avaliação física do corpo humano

Pós-graduação em Engenharia Mecânica - FEG

Dinâmica do aparelho locomotor em sujeitos amputados e não-amputados do membro inferior

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Dynamics of the interaction between body fluid and Ti cp: the influence of surface functionalization in the first stages of osseointegration

INTRODUCTION: Regenerative therapies using biomaterials require accurate information on interactions between the implanted material and the human body. To improve the process of bone regeneration it is necessary to obtain a better understanding of the influence of the surfaces on the early stages of osseointegration. This work aims to investigate the dynamic interaction between simulated body fluid (SBF) and titanium surfaces (Ti cp) immediately after their first contact. METHODS: Ti cp samples were passed through physicochemical treatments after immersion in acid solution, alkaline solution and solutions containing TiO2 and Ca2+, to obtain three different surfaces. These were characterized by electron microscopy and free energy estimates. The evaluation of the interaction with SBF was performed by measuring the dynamic contact angles after contacting the surfaces. RESULTS: The effects of SBF wettability were more significant on surfaces according to high energy estimates. A comparative analysis of the three types of surfaces showed that fluid spreading was greater in samples with greater polar components, indicating that the surface nature influences interactions in the early stages of osseointegration. CONCLUSION: The results indicate the influence of polar interactions in the dynamic wettability of the SBF. It is possible that these interactions can also influence cellular viability on surfaces. Based on these results, new experiments are being designed to improve the presented methodology as a tool for the evaluation of biomaterials without the need for in vivo experiments.

O Método de Kane aplicado a um modelo de corpo humano para obtenção da pressão intradiscal na coluna lombar

Nos últimos anos tem surgido vários métodos para se estudar sistemas multicorpos. A vantagem destes métodos é a obtenção das equações do movimento de forma mais fácil e precisa. Robôs, manipuladores, mecanismos, satélites, máquinas em geral e sistemas biomcânicos, pelas suas características, podem ser vantajosamente tratados por formalismo multicorpo, mas precisamente, o método de Kane a um modelo do corpo humano, com a finalidade de se determinar a pressão intradiscal entre as vértebras L4/L5 da coluna lombar, em algumas atividades normais de vida diária, como: sentar, abaixar, pegar e elevar cargas, realizar movimentos de flexão e extensão. Pretendeu-se, também obter os esforços internos nas diversas articulações deste modelo. A pressão intradiscal representa um parâmetro importante para caracterizar a sobrecarga na coluna, podendo ter relação com a degeneração do disco intervertebral, o que produz muita dor em indivíduos. Inicialmente, o modelo foi proposto e o método de Kane foi aplicado para se obter as equações do movimento. Para resolvê-las, foi necessário realiza a filmagem de um sujeito realizando as atividades citadas, a fim de se obter as equações das trajetórias dos diversos segmentos do corpo humano. Após a simulação, os parâmetros desejados foram obtidos e comparados com valores experimentais citados na literatura.

Relações públicas e o Brand Management: storytelling 2.0 na construção de relacionamentos

According to the Informational Society of the twentieth century, man develops society of the spectacle, where life becomes virtual and the individual ceases to be a spectator becoming the protagonist of wikiciberepopéia and organizations seeking to gain the attention and time of its consumers through new communication strategies. If the great epics of mankind brought mythical heroes, divine, with powers (mostly above the mortals), in the era of new technologies, the common man is in the hands the opportunity to become the hero of his own ciberepopéia. Increasingly resistant to traditional advertising, the new model of media consumer, the prosumer, the storytelling is transforming into one of the main communication tools of contemporary organizations. Offer your audience a creative and relevant content across several media platforms is a major brand positioning strategies currently used, in addition to providing the transmission of values and organizational principles in a subjective manner. Storytelling where objects are extensions of the human body (eg, the cell can be treated as an extension of the ears) is a strong indication of a technocratic society, because we can consider the new technologies as extensions of the human brain (as new store technologies, create meanings, share information through a specific language) and the individual who is on the edge of new technology ends up being excluded from certain social events. This new world tends to put an end to separation between seemingly contrary ideas, such as reality/fiction, natural/cultural and the man who emerges from this medium is not the creator, but rather, transforming what already exists. The current human evolution takes place from about half the human mind and tell stories that go beyond the media saturation that really emocionem and who have a real meaning for those who listen, to be interconnected with the socio-environmental reality of this new consumer, is a major chall...

Efeitos do estímulo auditivo musical sobre a resposta autonômica cardíaca e parâmetros cardiorrespiratórios durante e após exercício submáximo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Utilização de material alternativo para a obtenção e caracterização de biomodelos, por meio da técnica de impressão 3DPRINTER

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Corpo, comunicação e educação

O objetivo deste artigo é discutir as dificuldades de comunicação de conteúdos relacionados ao corpo humano, no contexto dos processos de ensino e de aprendizagem na escola fundamental e média. Através da exposição das necessidades dos alunos e das reticências dos professores, apresenta-se algumas teorias sociais como estratégia mediadora e viabilizadora do melhor desempenho da ação pedagógica e da contribuição escolar para a constituição do educando enquanto sujeito social.

Obtaining of Nanoapatite in Ti-7.5Mo Surface After Nanotube Growth

Titanium and their alloys have been used for biomedical applications due their excellent mechanical properties, corrosion resistance and biocompatibility. However, they are considered bioinerts materials because when they are inserted into the human body they are cannot form a chemical bond with bone. In several studies, the authors have attempted to modify their characteristic with treatments that changes the material surface. The purpose of this work was to evaluate obtaining of nanoapatite after growing of the nanotubes in surface of Ti-7.5Mo alloy. Alloy was obtained from c.p. titanium and molibdenium by using an arc-melting furnace. Ingots were submitted to heat treatment and they were cold worked by swaging. Nanotubes were processed using anodic oxidation of alloy in electrolyte solution. Surfaces were investigated using scanning electron microscope (SEM), FEG-SEM and thin-film x-ray diffraction. The results indicate that nanoapatite coating could form on surface of Ti-7.5Mo experimental alloy after nanotubes growth.

Preparation and Characterization of Ti-15Mo Alloy used as Biomaterial

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)